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Hyperacusis (Phonophobia)

An abnormally disproportionate increase in the sensation of loudness in response to auditory stimuli of normal volume. COCHLEAR DISEASES; VESTIBULOCOCHLEAR NERVE DISEASES; FACIAL NERVE DISEASES; STAPES SURGERY; and other disorders may be associated with this condition.
Also Known As:
Phonophobia; Hyperacusia; Loudness Perception Disturbances; Auditory Hyperesthesias; Disturbance, Loudness Perception; Disturbances, Loudness Perception; Hyperacuses; Hyperacusias; Hyperesthesia, Auditory; Hyperesthesias, Auditory; Loudness Perception Disturbance; Loudness Recruitments; Perception Disturbance, Loudness; Perception Disturbances, Loudness; Phonophobias; Auditory Hyperesthesia; Loudness Recruitment; Recruitment, Loudness
Networked: 162 relevant articles (28 outcomes, 17 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Photophobia (Light Sensitivity)
2. Nausea
3. Migraine Disorders (Migraine)
4. Pain (Aches)
5. Vomiting

Experts

1. Derry, Sheena: 6 articles (01/2012 - 01/2010)
2. Moore, R Andrew: 6 articles (01/2012 - 01/2010)
3. Lipton, R B: 5 articles (01/2008 - 05/2000)
4. Silberstein, Stephen D: 4 articles (04/2011 - 11/2005)
5. Mathew, Ninan T: 4 articles (07/2009 - 03/2003)
6. Moore, Brian C J: 3 articles (09/2012 - 06/2008)
7. Cady, Roger: 3 articles (04/2012 - 01/2002)
8. Derry, Christopher J: 3 articles (01/2012 - 01/2012)
9. Dodick, David W: 3 articles (04/2011 - 12/2008)
10. Ho, Tony W: 3 articles (12/2010 - 12/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hyperacusis:
1. Sumatriptan (Imigran)FDA LinkGeneric
2. zolmitriptan (Zomig)FDA Link
3. Acetaminophen (Paracetamol)FDA LinkGeneric
4. almotriptan (Axert)FDA Link
5. Valproic Acid (Valproate, Semisodium)FDA LinkGeneric
6. Pain-FreeIBA
7. rizatriptan (Maxalt)FDA Link
03/01/2001 - "At 2 h, rizatriptan 10 mg was significantly more effective than placebo for pain relief (71% vs. 38%, P < 0.001), and for elimination of pain, nausea, photophobia, phonophobia and functional disability. "
01/01/2001 - "Rizatriptan was also superior to sumatriptan in terms of the proportions of patients with no nausea, phonophobia or photophobia, and patients with normal function 2 h after treatment intake (p < 0.05). "
11/28/2000 - "Of the evaluable patients who treated three migraine attacks with 10 mg of rizatriptan (with an additional interspersed placebo-treated attack in most patients), 216 of 252 (86%) had pain relief (reduction of pain to mild or none), 122 of 252 (48%) were pain free, 211 of 250 (84%) had no nausea, 163 of 251 (65%) had no photophobia, 182 of 252 (72%) had no phonophobia, 136 of 249 (55%) had no functional disability, and 233 of 252 (92%) had no need for escape medications at 2 hours after dosing in at least two of three attacks. "
01/01/2003 - "Rizatriptan was also superior to ergotamine/caffeine in the proportions of patients with no nausea, vomiting, phonophobia or photophobia and for patients with normal function 2 h after drug intake (p < or = 0.001). "
01/01/2012 - " comparison of sumatriptan with active treatments was limited to two studies, one comparing sumatriptan 20 mg and dihydroergotamine (DHE) 1 mg, and one comparing sumatriptan 20 mg with rizatriptan 10 mg. Intranasal sumatriptan is effective as an abortive treatment for acute migraine attacks, relieving pain, nausea, photophobia, phonophobia, and functional disability, but is associated with increased adverse events compared with placebo."
8. Naproxen (Naprosyn)FDA LinkGeneric
9. gamma-Aminobutyric Acid (GABA)IBA
10. SodiumIBA

Therapies and Procedures

1. Aftercare (After-Treatment)
2. Ear Protective Devices (Earplug)
3. Laser Therapy (Surgery, Laser)
4. Hearing Aids (Hearing Aid)
5. Stapes Surgery (Stapedectomy)