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Quinone Reductases

NAD(P)H:(quinone acceptor) oxidoreductases. A family that includes three enzymes which are distinguished by their sensitivity to various inhibitors. EC 1.6.99.2 (NAD(P)H DEHYDROGENASE (QUINONE);) is a flavoprotein which reduces various quinones in the presence of NADH or NADPH and is inhibited by dicoumarol. EC 1.6.99.5 (NADH dehydrogenase (quinone)) requires NADH, is inhibited by AMP and 2,4-dinitrophenol but not by dicoumarol or folic acid derivatives. EC 1.6.99.6 (NADPH dehydrogenase (quinone)) requires NADPH and is inhibited by dicoumarol and folic acid derivatives but not by 2,4-dinitrophenol.
Also Known As:
Menaquinone Reductases; Reductases, Menaquinone; Reductases, Quinone
Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Pezzuto, John M: 1 article (07/2015)
2. Hussain, Raja Azadar: 1 article (07/2015)
3. Badshah, Amin: 1 article (07/2015)
4. Kondratyuk, Tamara P: 1 article (07/2015)
5. Park, Eun-Jung: 1 article (07/2015)
6. Ahmed, Nadeem: 1 article (07/2015)
7. Ong, Winston: 1 article (11/2008)
8. McCarley, Robin L: 1 article (11/2008)
9. Cruciano, Angela C: 1 article (11/2008)
10. Yang, Yuming: 1 article (11/2008)

Related Diseases

1. Neoplasms (Cancer)
2. Rupture
3. Infection
4. Urinary Bladder Neoplasms (Bladder Cancer)

Related Drugs and Biologics

1. Oxidoreductases
2. Vitamin K 2 (Vitamin K2)
3. Succinic Acid (Succinate)
4. Uridine Diphosphate (UDP)
5. Transferases
6. Protons (Proton)
7. Liposomes (Liposome)
8. Glutathione (Reduced Glutathione)
9. Enzymes
10. 5-(1-aziridinyl)-2,4-dinitrobenzamide