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Pyruvate Decarboxylase (Decarboxylase, Pyruvate)

Catalyzes the decarboxylation of an alpha keto acid to an aldehyde and carbon dioxide. Thiamine pyrophosphate is an essential cofactor. In lower organisms, which ferment glucose to ethanol and carbon dioxide, the enzyme irreversibly decarboxylates pyruvate to acetaldehyde. EC 4.1.1.1.
Also Known As:
Decarboxylase, Pyruvate; 2 Oxo Acid Carboxy Lyase; Acid Carboxy-Lyase, 2-Oxo; Carboxy-Lyase, 2-Oxo Acid; Carboxylase, alpha-Ketoacid; Decarboxylase, Pyruvic; alpha Carboxylase; alpha Ketoacid Carboxylase; 2-Oxo Acid Carboxy-Lyase; Pyruvic Decarboxylase; alpha-Carboxylase; alpha-Ketoacid Carboxylase
Networked: 43 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Duan, Jiu-Ju: 2 articles (03/2008 - 10/2006)
2. Guo, Shi-Rong: 2 articles (03/2008 - 10/2006)
3. Kang, Yun-Yan: 2 articles (03/2008 - 10/2006)
4. Kato-Noguchi, Hisashi: 2 articles (07/2004 - 05/2003)
5. Igamberdiev, Abir U: 1 article (06/2022)
6. Vanlerberghe, Greg C: 1 article (06/2022)
7. Zafari, Somaieh: 1 article (06/2022)
8. Liu, Dan: 1 article (05/2022)
9. Ma, Jiawei: 1 article (05/2022)
10. Ruan, Zhongqiang: 1 article (05/2022)

Related Diseases

1. Hypoxia (Hypoxemia)
2. Leigh Disease (Leigh's Disease)
3. Brain Diseases (Brain Disorder)
4. Lactic Acidosis
5. Pyruvate Dehydrogenase Complex Deficiency Disease

Related Drugs and Biologics

1. Alcohol Dehydrogenase (Alcohol Dehydrogenase (NAD+))
2. Oxidoreductases (Dehydrogenase)
3. Lactic Acid (Lactate)
4. Thiamine (Aneurin)
5. Pyruvate Carboxylase
6. Dihydrolipoamide Dehydrogenase (Lipoamide Dehydrogenase)
7. Adenosine Triphosphate (ATP)
8. Transketolase
9. Enzymes
10. Pyruvic Acid (Pyruvate)