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Pyroglutamyl-Peptidase I

An enzyme that catalyzes the release of a N-terminal pyroglutamyl group from a polypeptide provided the next residue is not proline. It is inhibited by thiol-blocking reagents and occurs in mammalian tissues, microorganisms, and plants. (From Enzyme Nomenclature, 1992) EC 3.4.19.3.
Also Known As:
Pyroglutamyl-Peptide Hydrolase; 5 Oxoprolyl Peptidase; Aminopeptidase, Pyroglutamate; I, Pyroglutamyl-Peptidase; Peptidase, Pyrrolidonecarboxylate; Peptidase, Pyrrolidonyl; Pyroglutamyl Peptidase I; Pyroglutamyl Peptide Hydrolase; 5-Oxoprolyl-Peptidase; Pyroglutamate Aminopeptidase; Pyrrolidonecarboxylate Peptidase; Pyrrolidonyl Peptidase
Networked: 9 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Larrinaga, Gorka: 4 articles (01/2015 - 02/2007)
2. López, José I: 3 articles (01/2015 - 02/2007)
3. Blanco, Lorena: 3 articles (01/2015 - 02/2007)
4. Perez, Itxaro: 3 articles (01/2015 - 11/2011)
5. Sanz, Begoña: 3 articles (01/2015 - 11/2011)
6. Gil, Javier: 2 articles (01/2015 - 02/2007)
7. Errarte, Peio: 2 articles (01/2015 - 01/2013)
8. Beitia, Maider: 2 articles (01/2015 - 01/2013)
9. Santaolalla, Francisco: 2 articles (01/2013 - 11/2011)
10. Pinto, Francisco M: 1 article (01/2015)

Related Diseases

1. Neoplasms (Cancer)
2. Wounds and Injuries (Trauma)
3. Tonsillitis
4. Thyroid Neoplasms (Thyroid Cancer)
5. Kidney Neoplasms (Kidney Cancer)

Related Drugs and Biologics

1. aminopeptidase B
2. Glutamyl Aminopeptidase (Aspartyl Aminopeptidase)
3. prolyl oligopeptidase (prolyl endopeptidase)
4. Protein Phosphatase 1
5. OSM-LIF Receptors
6. CD13 Antigens (Alanine Aminopeptidase)
7. Dipeptidyl Peptidase 4 (Dipeptidyl Peptidase IV)
8. Trypsin
9. Thyrotropin-Releasing Hormone (Protirelin)
10. Sodium Chloride (Saline Solution)