Pyroglutamyl-Peptidase I
An enzyme that catalyzes the release of a N-terminal pyroglutamyl group from a polypeptide provided the next residue is not proline. It is inhibited by thiol-blocking reagents and occurs in mammalian tissues, microorganisms, and plants. (From Enzyme Nomenclature, 1992) EC 3.4.19.3.
Also Known As:
Pyroglutamyl-Peptide Hydrolase; 5 Oxoprolyl Peptidase; Aminopeptidase, Pyroglutamate; Peptidase, Pyrrolidonecarboxylate; Peptidase, Pyrrolidonyl; Pyroglutamyl Peptidase I; Pyroglutamyl Peptide Hydrolase; 5-Oxoprolyl-Peptidase; Pyroglutamate Aminopeptidase; Pyrrolidonecarboxylate Peptidase; Pyrrolidonyl Peptidase
Networked: 12
relevant articles (0 outcomes,
0 trials/studies)
Bio-Agent Context: Research Results
Experts
1. | Larrinaga, Gorka:
4 articles
(01/2015 - 02/2007)
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2. | Blanco, Lorena:
3 articles
(01/2015 - 02/2007)
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3. | López, José I:
3 articles
(01/2015 - 02/2007)
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4. | Perez, Itxaro:
3 articles
(01/2015 - 11/2011)
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5. | Sanz, Begoña:
3 articles
(01/2015 - 11/2011)
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6. | Beitia, Maider:
2 articles
(01/2015 - 01/2013)
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7. | Errarte, Peio:
2 articles
(01/2015 - 01/2013)
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8. | Gil, Javier:
2 articles
(01/2015 - 02/2007)
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9. | Santaolalla, Francisco:
2 articles
(01/2013 - 11/2011)
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10. | Fu, Yi-Xuan:
1 article
(10/2021)
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Related Diseases
1. | Neoplasms (Cancer)
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2. | Wounds and Injuries (Trauma)
01/01/2013
- " Upregulation of low-density lipoprotein receptor, protein phosphatase 1, regulatory subunit 3C, ring-finger protein 11, pyroglutamyl-peptidase I, bactericidal/permeability-increasing protein, integrin, αD, BCL2-like 11, leukemia inhibitory factor receptor, ATPase, Cu transporting, α polypeptide, and Mk1 protein was found in estrogen-treated trauma-hemorrhaged animals. "
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3. | Tonsillitis
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4. | Thyroid Neoplasms (Thyroid Cancer)
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5. | Kidney Neoplasms (Kidney Cancer)
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Related Drugs and Biologics