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Pyridones

Pyridine derivatives with one or more keto groups on the ring.

Also Known As:

Pyridinones

Networked: 14 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - Pyridones: 14

Experts

1.	Gassman, Natalie R: 1 article (01/2021)
2.	Hayat, Faisal: 1 article (01/2021)
3.	Makarov, Mikhail V: 1 article (01/2021)
4.	McPherson, Pamela: 1 article (01/2021)
5.	Migaud, Marie E: 1 article (01/2021)
6.	Sonavane, Manoj: 1 article (01/2021)
7.	Trammell, Samuel A J: 1 article (01/2021)
8.	Ali, Ibrahim A I: 1 article (01/2021)
9.	Boraei, Ahmed T A: 1 article (01/2021)
10.	Eltamany, Elsayed H: 1 article (01/2021)

Related Diseases

1.	Obesity 08/15/2015 - "As part of our search for safe and effective MCH-R1 antagonists for the treatment of obesity, two series of pyridones and pyridazinones were evaluated. "
2.	Neoplasms (Cancer) 06/01/1977 - "[Anti-tumor activities of some seventy compounds related to lactams and pyridones (author's transl)]." 04/01/2003 - "In conclusion (a) rat hepatocytes have a much greater capacity to take up NTBI than the rat hepatoma cell line (Q7), (b) all chelators bind NTBI much more effectively during the uptake phase than in the mobilization of Fe which has been stored from NTBI and (c) while DFP is the most active chelator, other multidentate pyridinones have potential in the treatment of Fe overload, particularly at lower, more readily clinically available concentrations, and during cancer chemotherapy, by removing plasma NTBI."
3.	Acute Kidney Injury (Acute Renal Failure) 01/24/2021 - "As catabolites of nicotinamide possess physiological relevance, pyridones are often included in metabolomics measurements and associated with pathological outcomes in acute kidney injury (AKI). "
4.	Tinea (Ringworm) 01/01/1981 - "However, in many cases a two-steps synthesis may be of advantage in preparative respect, the ketoesters being cyclized to 2-pyrones (7), which then are reacted with hydroxylamine in the presence of certain bases to give 4. The hydroxy-pyridones show pronounced antifungal activity in vitro as well as in experimental guinea pig dermatophytosis."
5.	Neuralgia (Stump Neuralgia) 08/15/2013 - "Synthesis and the 5-HT6 receptor antagonistic effect of 3-arylsulfonylamino-5,6-dihydro-6-substituted pyrazolo[3,4]pyridinones for neuropathic pain treatment."

Related Drugs and Biologics

1.	Singlet Oxygen
2.	Hydroxylamine (Hydroxylamine Hydrochloride)
3.	RNA-Directed DNA Polymerase (Reverse Transcriptase)
4.	Peptides (Polypeptides)
5.	Niacinamide (Nicotinamide)
6.	Lactams
7.	Isoflurophate (DFP)
8.	Iron
9.	Iodides
10.	Deferoxamine (Desferal)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)