HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Thrombotic Thrombocytopenic Purpura

An acquired, congenital, or familial disorder caused by PLATELET AGGREGATION with THROMBOSIS in terminal arterioles and capillaries. Clinical features include THROMBOCYTOPENIA; HEMOLYTIC ANEMIA; AZOTEMIA; FEVER; and thrombotic microangiopathy. The classical form also includes neurological symptoms and end-organ damage, such as RENAL FAILURE.
Also Known As:
Purpura, Thrombotic Thrombocytopenic; Congenital Thrombotic Thrombocytopenic Purpura; Familial Thrombotic Thrombocytopenic Purpura; Moschcowitz Disease; Schulman-Upshaw Syndrome; Disease, Moschcowitz; Disease, Moschkowitz; Purpuras, Thrombotic Thrombocytopenic; Purpuras, Thrombotic Thrombopenic; Schulman Upshaw Syndrome; Syndrome, Schulman-Upshaw; Thrombocytopenic Purpura, Thrombotic; Thrombocytopenic Purpuras, Thrombotic; Thrombopenic Purpura, Thrombotic; Thrombopenic Purpuras, Thrombotic; Thrombotic Thrombocytopenic Purpuras; Thrombotic Thrombopenic Purpura; Thrombotic Thrombopenic Purpuras; Moschkowitz Disease; Purpura, Thrombotic Thrombopenic; Thrombotic Thrombocytopenic Purpura, Congenital; Thrombotic Thrombocytopenic Purpura, Familial
Networked: 2396 relevant articles (126 outcomes, 74 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Hemolytic-Uremic Syndrome
2. Thrombocytopenia (Thrombopenia)
3. Thrombotic Microangiopathies
4. Anemia
5. Myasthenia Gravis

Experts

1. George, James N: 56 articles (12/2015 - 01/2002)
2. Fujimura, Yoshihiro: 43 articles (07/2015 - 05/2002)
3. Matsumoto, Masanori: 40 articles (10/2015 - 05/2002)
4. Lämmle, Bernhard: 37 articles (02/2015 - 01/2002)
5. Vesely, Sara K: 33 articles (05/2015 - 01/2003)
6. Kremer Hovinga, Johanna A: 33 articles (02/2015 - 08/2003)
7. Tsai, Han-Mou: 31 articles (10/2014 - 01/2002)
8. Veyradier, Agnès: 29 articles (12/2015 - 04/2002)
9. Terrell, Deirdra R: 27 articles (05/2015 - 01/2003)
10. Coppo, Paul: 21 articles (12/2015 - 05/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Thrombotic Thrombocytopenic Purpura:
1. thymidine 5'-triphosphate (TTP)IBA
2. rituximab (Mabthera)FDA Link
3. Vincristine (Oncovin)FDA LinkGeneric
4. von Willebrand FactorIBA
5. Adrenal Cortex Hormones (Corticosteroids)IBA
6. SteroidsIBA
7. Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
8. Immunoglobulin G (IgG)IBA
9. Immunoglobulins (Immunoglobulin)IBA
10. Aspirin (Acetylsalicylic Acid)FDA LinkGeneric

Therapies and Procedures

1. Plasma Exchange
2. Plasmapheresis
3. Splenectomy
4. Bone Marrow Transplantation (Transplantation, Bone Marrow)
5. Blood Component Removal (Apheresis)