|3.||Autoimmune Hemolytic Anemia (Cold Agglutinin Disease)
|5.||Systemic Lupus Erythematosus (Libman-Sacks Disease)
|1.||Bussel, James B: 38 articles (06/2012 - 03/2002)|
|2.||McMillan, Robert: 16 articles (03/2009 - 08/2002)|
|3.||George, James N: 14 articles (03/2010 - 06/2003)|
|4.||Stasi, Roberto: 11 articles (06/2012 - 04/2004)|
|5.||Buchanan, George R: 10 articles (04/2010 - 02/2004)|
|6.||Michel, Marc: 9 articles (09/2014 - 10/2003)|
|7.||Cooper, Nichola: 9 articles (06/2012 - 03/2002)|
|8.||Tarantino, Michael D: 9 articles (02/2010 - 06/2003)|
|9.||Godeau, Bertrand: 8 articles (09/2014 - 12/2003)|
|10.||Bussel, J B: 8 articles (08/2012 - 01/2000)|
|1.||Inosine Triphosphate (ITP)IBA
01/01/1992 - "In one case, remission of AIHA allowed the donor's PBMC to successfully reconstitute SCID mice, despite the fact that the donor had developed immune thrombocytopenic purpura (ITP). "
02/01/2007 - "Immune thrombocytopenic purpura diagnosed in adolescence is more likely to be chronic then in childhood ITP, but has a higher rate of spontaneous resolution than in adults. "
12/01/2006 - "Recurrent immune thrombocytopenic purpura (ITP) is defined as the recurrence of ITP after at least 3 months of remission sustained without treatment. "
10/06/2008 - "To determine whether Helicobacter pylori eradication is an effective treatment for Australian patients with chronic immune thrombocytopenic purpura (ITP). "
08/01/2008 - "Corticosteroid (CS) therapy is effective in many patients with immune thrombocytopenic purpura (ITP), although it is associated with adverse effects. "
|2.||rituximab (Mabthera)FDA Link
03/01/2011 - "Very long-term remission induced by short-term rituximab monotherapy in a patient with heavily pretreated, chronic immune thrombocytopenic purpura."
06/01/2006 - "Rituximab in the management of chronic immune thrombocytopenic purpura: an effective and safe therapeutic alternative in refractory patients."
08/01/2004 - "Rituximab is effective for selected patients with chronic steroid-refractory immune thrombocytopenic purpura."
01/01/2006 - "Rituximab appears to constitute a safe and effective treatment for refractory immune thrombocytopenic purpura associated with SLE in patients having a contraindication to or refractory to conventional therapy."
02/01/2005 - "Rituximab may be a useful treatment for chronic immune thrombocytopenic purpura in children with a >50% CR rate lasting an average of 13 months, with 9 of 15 CRs ongoing (8 lasted 6 months or longer). "
|3.||Intravenous Immunoglobulins (IVIG)FDA Link
07/01/2005 - "Then it has been shown to be effective in the treatment of patients with thrombocytopenic purpura, and in the last decade, IVIG has been used in the treatment of many autoimmune and systemic inflammatory diseases. "
03/01/1999 - "The influence of Epstein-Barr virus seropositivity on the efficacy of intravenous immune globulin in children with immune thrombocytopenic purpura."
05/01/1997 - "Safety and efficacy of low-dose intravenous immune globulin (IVIG) treatment for infants and children with immune thrombocytopenic purpura. "
01/01/2007 - "Our study showed that IVIG blocked IFN-gamma signaling and IFN-gamma-induced gene expression and suppressed IFN-gamma function in vivo during immune responses to Listeria monocytogenes and in an IFN-gamma-enhanced model of immune thrombocytopenic purpura. "
01/01/1985 - "A multicenter European trial of intravenous immune globulin in immune thrombocytopenic purpura in childhood."
12/01/2005 - "In this preliminary study, the value of different platelet parameters, measured by the ADVIA120 Analyzer, in predicting the immediate response to intravenous immunoglobulin or intravenous anti-RhoD was assessed in 31 patients with immune thrombocytopenic purpura. "
10/01/2003 - "Low-dose versus high-dose immunoglobulin for primary treatment of acute immune thrombocytopenic purpura in children: results of a prospective, randomized single-center trial."
01/01/2003 - "Efficacy, tolerability, safety and pharmacokinetics of a nanofiltered intravenous immunoglobulin: studies in patients with immune thrombocytopenic purpura and primary immunodeficiencies."
01/01/2015 - "He was followed up for his immune thrombocytopenic purpura and received different treatment regimens none of which were adequately successful except intravenous immunoglobulin that was only temporarily effective. "
02/01/2014 - "Intravenous immunoglobulin is the favored therapy in childhood immune thrombocytopenic purpura. "
|5.||Immunoglobulin G (IgG)IBA
09/01/1995 - "Platelet associated IgG in chronic relapsing thrombocytopenic purpura in remission."
09/01/1984 - "Studies of platelet-associated IgG and in vivo platelet survival demonstrated immune-mediated destruction of platelets consistent with immune thrombocytopenic purpura. "
03/01/2005 - "Evidence suggests that amelioration of childhood immune thrombocytopenic purpura and some other autoimmune states by intravenous normal IgG is due to the following chain of events: (1) cross-linking of Fcgamma-receptors on blood effector cells; (2) release of mediators from these cells, often yielding an infusion-related reaction; (3) mediator-induced development of a cytokine field characterized by a mutually stabilizing Th2 polarization of CD4 T lymphocytes and alternative activation of macrophages; (4) selective quiescence of these macrophages towards targets coated with IgG autoantibody, due to increased expression of the macrophage Fcgamma-receptor IIB. "
11/01/1999 - "Corticosteroid prophylaxis for neurologic complications of intravenous immunoglobulin G therapy in childhood immune thrombocytopenic purpura."
02/01/1997 - "Neurologic complications of treatment of childhood acute immune thrombocytopenic purpura with intravenously administered immunoglobulin G."
|6.||RHO(D) antibody (anti-D)IBA
06/01/2010 - "Efficacy and safety of anti-D for immune thrombocytopenic purpura in children."
01/01/2007 - "Immune thrombocytopenic purpura associated with renal disease is usually therapy-related, occurring after administration of intravenous immunoglobulin therapy or anti-D. "
11/01/2003 - "Use of intravenous anti-D in patients with refractory and relapsed immune thrombocytopenic purpura."
11/01/2003 - "Initial management of immune thrombocytopenic purpura in adults: a randomized controlled trial comparing intermittent anti-D with routine care."
03/01/2001 - "A dose of 75 microg/kg/d of i.v. anti-D increases the platelet count more rapidly and for a longer period of time than 50 microg/kg/d in adults with immune thrombocytopenic purpura."
02/01/2009 - "Improved quality of life for romiplostim-treated patients with chronic immune thrombocytopenic purpura: results from two randomized, placebo-controlled trials."
02/02/2008 - "Efficacy of romiplostim in patients with chronic immune thrombocytopenic purpura: a double-blind randomised controlled trial."
09/01/2009 - "A phase II, open-label, sequential-cohort, dose-escalation study of romiplostim in Japanese patients with chronic immune thrombocytopenic purpura."
01/01/2015 - "Treatment of acquired amegakaryocytic thrombocytopenic purpura with romiplostim."
05/01/2014 - "Pseudothrombocytopenia in a patient receiving romiplostim for immune thrombocytopenic purpura."
|8.||Adrenal Cortex Hormones (Corticosteroids)IBA
01/01/1982 - "Remission of post-transfusion thrombocytopenic purpura with high dose intravenous corticosteroids."
01/01/2013 - "A 2 year old Tunisian child presented with chronic thrombopenic purpura which failed to respond to corticosteroids. "
09/06/2004 - "The immune thrombocytopenic purpura was successfully treated with anti-tuberculous drugs combined with corticosteroids and high dose immune globulin therapy. "
10/01/1993 - "Intravenous corticosteroids versus intravenous gammaglobulin in the treatment of acute immune thrombocytopenic purpura."
01/01/1973 - "[The place corticosteroids in the treatment of idiopathic thrombopenic purpura]."
|9.||Danazol (Azol)FDA LinkGeneric
12/01/1988 - "Danazol seems to be effective in the treatment of children with immune thrombocytopenic purpura and would warrant additional studies to determine its proper role in the management of this common pediatric ailment."
09/01/1985 - "The use of danazol in the management of chronic immune thrombocytopenic purpura."
03/01/1999 - "Danazol therapy in cyclic acquired amegakaryocytic thrombocytopenic purpura: a case report."
08/01/1995 - "Thrombocytopenic purpura following treatment with danazol."
07/01/1995 - "[Treatment of idiopathic thrombopenic purpura with danazol]."
01/01/2015 - "An improved flow cytometric immunobead array to detect autoantibodies in plasma from patients with immune thrombocytopenic purpura."
10/01/1989 - "Immunochemical analysis of platelet autoantibodies in HIV-related thrombocytopenic purpura: a study of 68 patients."
09/01/2009 - "Immune thrombocytopenic purpura is an acquired disorder, in which accelerated platelet consumption is due to platelet autoantibodies. "
08/01/2009 - "We characterized a novel GPVI-deficient patient with immune thrombocytopenic purpura and searched for the presence of anti-GPVI autoantibodies in this and another patient with GPVI deficiency. "
09/01/1998 - "Platelet autoantibodies in immune thrombocytopenic purpura."
03/01/1993 - "Splenectomy is a safe and effective treatment in HIV-infected patients with severe symptomatic thrombocytopenic purpura resistant to medical therapy."
10/01/2013 - "[Multivariate analysis of the efficacy of laparoscopic splenectomy in the treatment of immune thrombocytopenic purpura]."
10/01/1991 - "The site of platelet destruction in thrombocytopenic purpura as a predictive index of the efficacy of splenectomy."
02/01/1986 - "In six patients with thrombocytopenic purpura not cured by splenectomy platelets fell to less than 150 X 10(9)/l within six weeks of splenectomy. "
08/01/2006 - "Predictive factors for successful laparoscopic splenectomy in immune thrombocytopenic purpura: study of clinical and laboratory data."
|2.||Drug Therapy (Chemotherapy)
12/01/2004 - "This article discusses the pros and cons of drug therapy for immune thrombocytopenic purpura in children."
12/01/2004 - "The pros and cons of drug therapy for immune thrombocytopenic purpura in children."
02/01/2004 - "The child with immune thrombocytopenic purpura: is pharmacotherapy or watchful waiting the best initial management? "
02/01/2000 - "Thrombocytopenic purpura resolved 2 months after discontinuation of plasma exchange while the patient received chemotherapy. "
01/01/2006 - "A newly diagnosed patient with metastatic pancreatic adenocarcinoma developed thrombocytopenic purpura prior to initiation of chemotherapy. "
05/03/2001 - "Long-term outcomes after treatment for refractory immune thrombocytopenic purpura."
03/01/2014 - "Improvement of thrombocytopenia after treatment for Helicobacter pylori in a patient with immunologic thrombocytopenic purpura."
10/01/2004 - "Complete platelet recovery after treatment of Helicobacter pylori infection in a child with chronic immune thrombocytopenic purpura: a case report."
01/01/2010 - "The authors present a case report of a 39 years old patient who developed an ACS after treatment of immune thrombocytopenic purpura with human immunoglobulin. "
06/01/2013 - "Acute renal failure in a child with thrombocytopenic purpura caused by acute Epstein-Barr virus infection after treatment with anti-D immunoglobulin."
11/01/2013 - "The clinical presentation closely mimicked primary thrombocytopenic purpura and led to the ineffective use of plasma exchange. "
01/01/2012 - "Severe immune thrombocytopenic purpura treated with plasma exchange."
10/01/2005 - "[Plasma exchanges as treatment of severe acute immune thrombocytopenic purpura]."
09/01/1998 - "The Canadian experience using plasma exchange for immune thrombocytopenic purpura. "
01/01/1988 - "Combined plasma exchange and intravenous gammaglobulin in the treatment of patients with refractory immune thrombocytopenic purpura."
|5.||Platelet Transfusion (Blood Platelet Transfusions)
03/01/1991 - "[Intravascular platelet transfusion in utero for the treatment of immunologic thrombocytopenic purpura: a case report]."
03/01/1987 - "Thrombocytopenic purpura and platelet transfusion."
08/01/1994 - "[Refractory immune thrombocytopenic purpura accompanied with avascular necrosis of femoral head receiving the combination of high dose immunoglobulin therapy followed by platelet transfusion could successfully be managed to undergo surgery]."
10/01/2002 - "The methods are mostly used in serodiagnosis of neonatal thrombocytopenic purpura, posttransfusion purpura and refractoriness to platelet transfusion, and primary and secondary autoimmune thrombocytopenia."
07/26/1952 - "Thrombocytopenic purpura induced by sulfisoxazole (gantrisin) therapy; report of a case controlled by platelet transfusion."