Pseudorabies

1.	Tomioka, Yukiko: 2 articles (10/2007 - 11/2004)
2.	Cherel, Pierre: 2 articles (10/2007 - 11/2004)
3.	Ono, Etsuro: 2 articles (10/2007 - 11/2004)
4.	Watanabe, Yuki: 2 articles (10/2007 - 11/2004)
5.	Amagai, Keiko: 2 articles (10/2007 - 11/2004)
6.	Yong, Guo: 2 articles (06/2006 - 01/2006)
7.	Sánchez-Ramos, I: 1 article (10/2008)
8.	Escribano, J M: 1 article (10/2008)
9.	Gómez-Sebastián, S: 1 article (10/2008)
10.	Tabarés, E: 1 article (10/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Pseudorabies:

1.	VaccinesIBA 01/01/2006 - "In this article a panel of tests used for evaluation of safety and efficacy of inactivated as well as live Aujeszky's disease vaccines is described." 01/01/1979 - "Experimental studies in weaned pigs with three vaccines against Aujeszky's disease." 01/01/2006 - "Since Aujeszky's disease have become an economic problem in pig farms in late 1960's and early 1970's many different vaccines, either inactivated or live - attenuated were developed" 01/01/2006 - "Evaluation of efficacy and safety of Aujeszky's disease vaccines." 01/01/2005 - "Eradication of Aujeszky's disease from a large-scale pig farm by the 'test-and-cull' eradication procedure based on the use of gene-deleted vaccines and serological monitoring using gE ELISA is described" Order ALL the reference details at left...
2.	DNA (Deoxyribonucleic Acid)IBA 08/01/1975 - "Electron microscopic studies of the DNA of defective and standard pseudorabies virions." 12/01/1999 - "Detection of pseudorabies virus DNA in individual single-reactor pigs found in certified pseudorabies-free herds." 03/31/1999 - "Potency of an experimental DNA vaccine against Aujeszky's disease in pigs." 03/01/1998 - "Aujeszky's disease (AD) was diagnosed in seven dogs by histological examination, immunohistochemistry and DNA in-situ hybridization" 01/01/1998 - "A recombinant pseudorabies (Aujeszky's disease) virus (PrV) designated as vE16lac was constructed by deleting a 3-kbp DNA segment spanning the junction of long and short components of the viral genome, and by replacing the deleted segment with a lacZ-expression cassette" Order ALL the reference details at left...
3.	Glycoproteins (Glycoprotein)IBA 01/01/1998 - "Efficacy of a mixed glycoprotein vaccine against pseudorabies in pregnant sows." 01/01/2000 - "Whereas the relative contribution of several nonessential glycoproteins to neurovirulence and neurotropism of Pseudorabies virus (PrV), an alphaherpesvirus which causes Aujeszky's disease in pigs, has recently been uncovered in studies using viral deletion mutants, the importance of essential glycoproteins is more difficult to assess" 03/01/1998 - "This trial was performed in a 350-sow farrow-to-finish pig farm in which animals had been vaccinated against Aujeszky's disease with glycoprotein gC deletion (gC(-)) vaccine" 10/01/2008 - "DIVA diagnostic of Aujeszky's disease using an insect-derived virus glycoprotein E." 11/01/2001 - "In the alphaherpesvirus pseudorabies virus (PrV), the causative agent of Aujeszky's disease in pigs, the essential glycoprotein D (gD) mediates secondary attachment of virions to target cells by binding to newly identified cellular receptors (R" Order ALL the reference details at left...
4.	AntibodiesIBA 04/01/1997 - "We compared the ability of an ELISA to detect antibodies to Aujeszky's disease (pseudorabies) virus gE in colostrum (test A) and in a single droplet of whole blood (test B) with the results obtained in serum (gold standard) in the target population by constructing and analyzing such curves" 02/01/1995 - "Vaccination trial against Aujeszky's disease: development of antibody titers in sow serum, colostrum and the serum of suckling piglets and the influence of maternal antibodies on the serologic vaccination reaction of weaned piglets]" 11/26/2006 - "A few backyard breeder pigs had antibodies for pseudorabies in 2000 and 2002" 12/01/2004 - "The sensitivity of the solid - based test strip towards pseudorabies antibodies was high with a detection limit of 1 to 10,000 - dilution factor" 11/15/2003 - "Specificity of three ELISA-gE kits for screening pig meat for antibodies to Aujeszky's disease." Order ALL the reference details at left...
5.	Thymidine KinaseIBA 01/30/1984 - "During a study designed to identify changes in the genomes that are observed in mutant populations of pseudorabies virions, a thymidine kinase-defective population of virions which contains genomes that possess inverted repeated sequences of unequal sizes has been identified" 08/01/1992 - "In order to compare the effect of the route of immunization on the efficacy of a modified live Aujeszky's disease (AD) vaccine, which had deletions in both thymidine kinase (TK-) and glycoprotein gIII genes (gpIII-), 20 six-week-old pigs were vaccinated by either the intramuscular (IM) (n = 10) or subcutaneous (SC) (n = 10) route" 01/01/1994 - "Simultaneous inoculation of 50 doses of two modified live pseudorabies vaccines with either functional (strain Bartha) or inactivated (strain Begonia) thymidine kinase into piglets of 1 week of age did not induce any clinical signs of Aujeszky's disease" 06/01/1992 - "Twenty four cloned isolates of Aujeszky's disease virus collected from outbreaks of Aujeszky's disease from 1981 through 1989 in Japan were characterized by their restriction endonuclease (RE) cleavage patterns, virulence for mice and thymidine kinase (TK) activity" 11/03/1990 - "Safety of an Aujeszky's disease vaccine based on deletion mutant strain 783 which does not express thymidine kinase and glycoprotein I." Order ALL the reference details at left...
6.	Acyclovir (Aciclovir)FDA LinkGeneric 01/01/1992 - "The combined antiviral effects of some flavonoid compounds and acycloguanosine (acyclovir, Zovirax) were studied on the multiplication of herpes simplex virus types 1 and 2 in HEp-2 cells and on pseudorabies (Aujeszky) virus in chick embryo fibroblast cells by the yield reduction method" 08/01/1983 - "Relative activities of acyclovir and BW759 against Aujeszky's disease and equine rhinopneumonitis viruses." 06/01/1985 - "Chemotherapy of Aujeszky's disease (pseudorabies) in the mouse by means of nucleoside analogues: bromovinyldeoxyuridine, acyclovir, and dihydroxypropoxymethylguanine." 01/01/1990 - "The antiviral effect of the combination acyclovir (ACV) and ribavirin (R) on herpes simplex virus type 1 (HSV-1) in diploid cell culture of human embryonal skin and muscle fibroblasts and the virus of pseudorabies in secondary culture of chicken embryonal fibroblasts is studied" 08/01/1983 - "Compound BW759 (9-[2-hydroxy-1-(hydroxymethyl)ethoxymethyl]guanine) was shown to be about 230 times more active than acyclovir (9-[2-hydroxyethoxymethyl]guanine) (ACV) against Equid herpesvirus type 1 infection in Syrian hamsters and was more effective against Aujeszky's disease in mice" Order ALL the reference details at left...
7.	A-Form DNA (A-DNA)IBA 06/01/2001 - "In an attempt to produce a DNA vaccine to prevent Aujeszky's disease, the induction of immune responses against Aujeszky's disease virus (ADV) gD was investigated in mice" 03/01/1962 - "Analysis of the intracellular development of a DNA-containing mammalian virus (pseudorabies) by means of ultraviolet light irradiation." 09/20/1999 - "Our results thus demonstrate for the first time that the application of porcine GM-CSF gene in a DNA vaccine formulation can exert immuno-adjuvant and protective effects with single vaccination in the natural host pig against Aujeszky's disease." Order ALL the reference details at left...
8.	GuanineIBA 07/01/1988 - "Therapy of Aujeszky's disease (pseudorabies) in naturally infected and artificially inoculated piglets using BW B759U (9-[1,3-dihydroxy-2-propoxymethyl] guanine)." 08/01/1983 - "Compound BW759 (9-[2-hydroxy-1-(hydroxymethyl)ethoxymethyl]guanine) was shown to be about 230 times more active than acyclovir (9-[2-hydroxyethoxymethyl]guanine) (ACV) against Equid herpesvirus type 1 infection in Syrian hamsters and was more effective against Aujeszky's disease in mice" Order ALL the reference details at left...
9.	prothymosin alphaIBA 12/01/2005 - "Previously, we showed that murine prothymosin alpha (ProT) enhances the efficacy of a pseudorabies DNA vaccine delivered by bacterial vectors" 07/16/2001 - "Prothymosin alpha enhances protective immune responses induced by oral DNA vaccination against pseudorabies delivered by Salmonella choleraesuis." Order ALL the reference details at left...
10.	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 09/20/1999 - "Our results thus demonstrate for the first time that the application of porcine GM-CSF gene in a DNA vaccine formulation can exert immuno-adjuvant and protective effects with single vaccination in the natural host pig against Aujeszky's disease." Order ALL the reference details at left...

Therapies and Procedures

1.	Chemical Sympathectomy 01/01/1995 - "To investigate the routes of neural spread of pseudorabies (Aujeszky's disease) virus (PRV), the effects of chemical sympathectomy by 6-hydroxydopamine (6-OHDA) on clinical signs and viral spread in mice inoculated intraocularly with PRV were examined" Order ALL the reference details at left...
2.	Drug Therapy (Chemotherapy) 06/01/1985 - "Chemotherapy of Aujeszky's disease (pseudorabies) in the mouse by means of nucleoside analogues: bromovinyldeoxyuridine, acyclovir, and dihydroxypropoxymethylguanine." Order ALL the reference details at left...

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