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Prothionamide (Protionamide)

Antitubercular agent similar in action and side effects to ETHIONAMIDE. It is used mostly in combination with other agents.
Also Known As:
Protionamide; Ektebin; Peteha; 4-Pyridinecarbothioamide, 2-propyl-
Networked: 92 relevant articles (4 outcomes, 7 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Jang, Seung Hun: 2 articles (10/2022 - 02/2013)
2. Tan, Yaoju: 2 articles (01/2018 - 01/2017)
3. Chu, Nai-hui: 2 articles (10/2013 - 12/2008)
4. Choi, Junyeong: 1 article (10/2022)
5. Jeong, Han Eol: 1 article (10/2022)
6. Jung, Sun-Young: 1 article (10/2022)
7. Oh, In-Sun: 1 article (10/2022)
8. Shin, Ju-Young: 1 article (10/2022)
9. Son, Hyunjin: 1 article (10/2022)
10. Adakun, Susan: 1 article (05/2022)

Related Diseases

1. Tuberculosis (Tuberculoses)
2. Leprosy (Hansen's Disease)
3. Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis)
4. Meningeal Tuberculosis (Tuberculous Meningitis)
5. Infections
06/01/1988 - "Mice inoculated with 4800 Mycobacterium leprae in the left hind foot pad were treated from day 62 to day 150 after infection with 50 mg or 150 mg of ofloxacin per kg body weight, 150 mg pefloxacin per kg, or 50 mg prothionamide per kg. These drugs were administered by esophageal cannula 5 days weekly with dapsone (0.01 g per 100 g diet). "
04/01/2019 - "In a mouse tuberculosis infection model, the efficacy of a cocktail of levofloxacin + pyrazinamide + protionamide + aminosalicylate against Mtb increased when the cocktail was combined with BP/CL, achieving efficacy similar to that of the positive control treatment (isoniazid + rifampin + pyrazinamide) after 2 months of treatment. "
12/16/1994 - "Renewed and lasting control of the infection was achieved only by continuous administration of steroids (prednisolone 10 mg twice daily) in conjunction with an unconventional antibiotic regimen consisting of amikacin, protionamide, terizidone, clarithromycin and sparfloxacin for some five months. "
08/01/2022 - "AFB: acid-fast bacilli; Amk: amikacin; Cs: cycloserine; CT: computed tomography; E: ethambutol; GeneXpert MTB/RIF: GeneXpert Mycobacterium tuberculosis and rifampicin resistance; H: isoniazid; IVF-ET: in-vitro fertilization-embryo transfer; Lzd: linezolid; Mfx: moxifloxacin; MTB: Mycobacterium tuberculosis; mNGS: next generation sequencing; MTB-DNA: Mycobacterium tuberculosis-deoxyribonucleic acid; Pto: protionamide; R: rifampicin; TB: tuberculosis; T-SPOT.TB: spot test of mycobacterium TB infection T-lymphocytes; Z: pyrazinamide."

Related Drugs and Biologics

1. Ethionamide (Trecator-SC)
2. Rifampin (Rifampicin)
3. Thioamides
4. Pyrazinamide
5. Clofazimine (Lamprene)
6. Isoniazid (Ftivazide)
7. Dapsone
8. Levofloxacin (Levaquin)
9. Ceftazidime (Fortum)
10. Ethambutol (Myambutol)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Therapeutics
3. Retreatment
4. Nephrectomy
5. Cannula