Protein-Energy Malnutrition (Marasmus)

Subscribe to Selected New Research on Protein-Energy Malnutrition

1207 relevant articles (24 outcomes, 125 trials/studies) found for this Disease

Description: The lack of sufficient energy or protein to meet the body's metabolic demands, as a result of either an inadequate dietary intake of protein, intake of poor quality dietary protein, increased demands due to disease, or increased nutrient losses.

Also Known As:

Marasmus; Protein-Calorie Malnutrition; Malnutrition, Protein-Calorie; Malnutrition, Protein-Energy; Malnutritions, Protein-Energy; Protein Calorie Malnutrition; Protein Energy Malnutrition

Relationship Network

Disease Context: Research Results

Nutritional and Metabolic Diseases

Nutrition Disorders: 189

Malnutrition: 7103

Deficiency Diseases: 383

Protein Deficiency: 755

Protein-Energy Malnutrition: 1207

Kwashiorkor: 560

Related Diseases

1.	Kwashiorkor
2.	Infection
3.	Malnutrition
4.	Diarrhea
5.	Crohn Disease (Crohn's Disease)

Experts

1.	Lee, Myung G: 8 articles (02/2008 - 01/2003)
2.	Kwon, Jong W: 7 articles (07/2005 - 04/2002)
3.	Kim, S G: 6 articles (10/2001 - 05/2000)
4.	Lee, M G: 6 articles (10/2001 - 05/2000)
5.	Cho, M K: 6 articles (10/2001 - 05/2000)
6.	Kim, Y G: 6 articles (10/2001 - 05/2000)
7.	Kim, Sang G: 5 articles (09/2004 - 04/2002)
8.	Lee, Myung Gull: 5 articles (07/2004 - 02/2002)
9.	Lee, Inchul: 4 articles (02/2008 - 09/2004)
10.	Shim, Chang-K: 4 articles (09/2004 - 04/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Protein-Energy Malnutrition:

1.	Vitamin A (Retinol)FDA Link 08/01/2008 - "Vitamin A status has been reported to be adversely affected in protein-energy malnutrition (PEM). " 03/01/2002 - "Relationship between protein-energy malnutrition, vitamin A, and parasitoses in living in Brasília." 06/01/1996 - "Significance of very low retinol levels during severe protein-energy malnutrition." 01/01/1988 - "Keratomalacia is caused by a deficiency of vitamin A itself and/or protein-calorie malnutrition. " 07/21/1984 - "To test whether large doses of vitamin A supplements prevented keratomalacia, a case-control analysis was done, with patients with severe protein-energy malnutrition being used as controls. " Order ALL the reference details at left...
2.	IronIBA 04/01/2003 - "RESULTS: The overall prevalence of iron deficiency anaemia (IDA) and protein energy malnutrition in the slum communities was 22.3% and 27.1% respectively. " 08/01/1997 - "Iron deficiency and protein-energy malnutrition, both highly prevalent, have the greatest public health importance in this regard. " 11/01/1996 - "Bone marrow and chelatable iron in patients with protein energy malnutrition." 01/01/1990 - "These findings suggest that hookworm may be an important determinant of chronic protein-energy malnutrition, as well as anaemia, in areas where diets are generally inadequate in protein, energy, and iron. " 02/01/1985 - "We evaluated the role of initial iron stores on iron accumulation during recovery from severe edematous protein-energy malnutrition in children. " Order ALL the reference details at left...
3.	Transferrin (beta 2 Transferrin)IBA 10/01/1981 - "Within 2--3 days of establishing protein-energy malnutrition (PEM) in primates there was a significant reduction (P less than 0.01) of the serum transferrin and C3 concentrations. " 08/01/1997 - "Transferrin kinetics are altered in children with severe protein-energy malnutrition." 01/01/1987 - "Plasma transferrin (TFN) levels are valid as markers of protein-calorie malnutrition (PCM). " 01/01/1984 - "[Transfer of 59Fe to reticulocytes from transferrin in the serum of children with signs of protein-calorie malnutrition]" 03/01/1975 - "These findings seem to question the validity of transferrin as a sensitive parameter for the detection of subtle protein energy malnutrition." Order ALL the reference details at left...
4.	Proteins (Proteins, Gene)IBA 02/01/1999 - "Levels of albumin and other proteins may be helpful in determining increased risk of morbidity and mortality, but better markers are needed for diagnosis of protein energy malnutrition per se." 02/01/2006 - "OBJECTIVE: In the clinical practice, visceral proteins are used as indirect markers of protein energy malnutrition (PEM), but their reliability could be reduced with advancing age. " 11/01/1992 - "The assessment of his nutritional status showed decrease in anthropometric measurements, visceral proteins and the Fischer ratio, which suggested that he was in the status of protein-calorie malnutrition in association with amino acid imbalance. " 01/01/1991 - "Changes in the levels of rapid turnover proteins (RTP) during total parenteral nutrition (TPN) were compared with changes in other nutritional measures in 40 adult patients with benign diseases who were considered to have moderate to severe protein-energy malnutrition on the basis of anthropometric measurements. " 11/13/1982 - "Nutritional studies conducted in 9 patients suffering from anorexia nervosa showed a marasmus-like pattern with predominant depletion of lean body mass rather than of visceral proteins. " Order ALL the reference details at left...
5.	Vegetable Proteins (Vegetable Protein)IBA 05/01/1971 - "Vegetable protein mixture in protein-calorie malnutrition." 04/28/1979 - "The present study was designed to test the comparative efficacy of cow's milk, a protein, vitamin and mineral mixture (PVM) and soybean textured vegetable protein (SOMOS) as supplements to maize meal porridge in the dietary treatment of children with protein energy malnutrition (PEM). " 07/01/1995 - " The Centre's strategic plan "To the Year 2000" incorporates the following goals: 1) improving the nutritional status of women and children by developing improved methods of assessing nutritional deficits and by developing nutritional intervention strategies, 2) improving the vitamin A status of infants and children by promoting home gardening and modified cooking procedures, 3) investigating the role of antioxidants in disease prevention and interventions, 4) testing the efficacy of vegetable protein sources in treating children with severe protein-energy malnutrition, 5) modifying breast-feeding practices, and 6) evaluating the losses of micronutrients during episodes of infection in order to define the optimum nutritional therapy. " Order ALL the reference details at left...
6.	Albendazole (Albenza)FDA Link 03/01/1990 - "We conclude that single dose treatment with albendazole, despite continual exposure to reinfection, can allow improved physical fitness in schoolboys in areas where soil-transmitted helminths and protein-energy malnutrition are highly prevalent." 07/01/1989 - "Single dose treatment with albendazole, despite continual exposure to infection, can permit improved growth rates in areas where intestinal helminths and protein-energy malnutrition are highly prevalent." Order ALL the reference details at left...
7.	alpha 1-Antitrypsin (alpha 1 Antitrypsin)IBA 08/01/1993 - "The intestinal clearance of alpha 1-antitrypsin was significantly higher than normal in the marasmus and marasmic kwashiorkor groups, and significantly lower than normal in the kwashiorkor group. " 08/01/1993 - "Serum alpha 1-antitrypsin concentrations were significantly higher than normal in the marasmus and marasmic kwashiorkor groups, and significantly lower than normal in the kwashiorkor group. " 08/01/1993 - "A commercially available radial immunodiffusion assay was used to measure serum and faecal alpha 1-antitrypsin concentrations as well as alpha 1-antitrypsin clearance in 17 children with kwashiorkor, 11 children with marasmic kwashiorkor, 10 children with marasmus, and 16 normal children. " 01/01/1991 - "Faecal clearance of alpha 1-antitrypsin was measured in patients with ulcerative colitis and Crohn's disease and compared with disease activity and markers of protein-calorie malnutrition. " 08/01/1993 - "There was a significant inverse correlation between the alpha 1-antitrypsin clearance and serum albumin concentration in the marasmus and marasmic kwashiorkor groups. " Order ALL the reference details at left...
8.	ZincIBA 10/01/2008 - "The aim of present study was to assess the association between serum zinc and oxidant/antioxidant status in children with protein energy malnutrition. " 12/01/2003 - "A randomized controlled study of the impact of dietary zinc supplementation in the management of children with protein-energy malnutrition in Lesotho. " 12/01/2003 - "A randomized controlled study of the impact of dietary zinc supplementation in the management of children with protein-energy malnutrition in Lesotho. " 09/01/1998 - "A randomized, double-blind trial was undertaken to measure the effects of zinc supplementation on catch-up growth in severe protein-energy malnutrition, with particular reference to linear growth. " 11/01/1980 - "Study of plasma zinc protein energy malnutrition." Order ALL the reference details at left...
9.	MicronutrientsIBA 08/01/1995 - "Most of the correlational and experimental studies that have tested the hypothesis that mild-to-moderate protein-energy malnutrition (PEM) has an adverse effect on cognitive development disregarded the potential confounder effect of micronutrients. " 08/05/2008 - "Protein-energy malnutrition, dietary micronutrient deficiencies, environmental toxins, and lack of early sensory stimulation or the ability to profit from it may contribute to neurodevelopmental disabilities. " 12/01/2006 - "Several developed and developing countries have implemented successful approaches to eliminate protein-energy malnutrition and micronutrient deficiencies with sustained impact. " 08/02/2005 - "Interventions to prevent protein- energy malnutrition range from promoting breast-feeding to food supplementation schemes, whereas micronutrient deficiencies would best be addressed through food-based strategies such as dietary diversification through home gardens and small livestock. " 01/01/2004 - "Due to control of florid and severe cases of protein-energy malnutrition, deficiencies of micronutrients in children have assumed public health importance. " Order ALL the reference details at left...
10.	Immunoglobulins (Immunoglobulin)IBA 03/01/2004 - "The objective of this study was to determine the effects of acute protein-energy malnutrition on serum levels of immunoglobulins and their subclasses in murine models. " 02/01/1994 - "Published studies on the serum immunoglobulin concentrations of patients with protein-energy malnutrition (PEM) have been contradictory. " 09/01/1972 - "A study of immunoglobulins in protein calorie malnutrition." 03/01/2004 - "Serum Levels of Th2-Type Immunoglobulins are Increased in Weanling Mice Subjected to Acute Wasting Protein-Energy Malnutrition." 10/01/1988 - "Serum immunoglobulins and B cell count in protein energy malnutrition." Order ALL the reference details at left...

Therapies and Procedures

1.	Nutritional Support (Artificial Feeding) 01/01/1988 - "However, based on a preliminary study, nutritional support may be required for periods longer than two weeks to show significant improvement in protein-calorie malnutrition. " 10/01/2006 - "Protein energy malnutrition is an important determinant of clinical outcome in older patients after hip fracture, but the effectiveness of nutritional support programs in routine clinical practice is controversial. " 07/01/2004 - "BACKGROUND: Adequate nutritional support of severe primary protein energy malnutrition (PEM) is indispensable for achieving normal immune response. " 02/01/2004 - "In elective gastrointestinal (GI) surgery, the patients' nutritional status should be assessed and if protein-energy malnutrition exists, preoperative nutritional support should be scheduled 7 to 14 days before surgery. " 01/01/1999 - "The usual indication for nutritional support at this tertiary referral and specialty hospital was actual or impending protein calorie malnutrition. " Order ALL the reference details at left...
2.	Parenteral Nutrition 07/01/2002 - "Very few pediatric studies have monitored nutritional status using normalized protein catabolic rate (nPCR) or treating protein-energy malnutrition (PEM) with intradialytic parenteral nutrition (IDPN). " 05/01/1997 - "Less well-proven techniques for the treatment of protein-energy malnutrition include intradialytic parenteral nutrition. " 02/01/1996 - "Taken in combination, current information suggests reserving the use of parenteral feeding for patients meeting objective criteria for protein-calorie malnutrition and making parsimonious use of lipid emulsion, especially in stressed patients." 03/01/1990 - "Parenteral nutrition is administered on a short-term basis to prevent further protein-energy malnutrition in debilitated calves that cannot or will not consume adequate quantities of milk. " 01/01/1989 - "[Parenteral nutrition in children with protein-calorie malnutrition]" Order ALL the reference details at left...
3.	Renal Dialysis (Hemodialysis) 01/01/2006 - "Despite improvement in many aspects of the care of maintenance hemodialysis (HD) patients, protein-calorie malnutrition, which is characterized by an insidious loss of somatic protein, is common and is a major risk factor for increased morbidity and mortality. " 01/01/2000 - "This prospective nonintervention single-center study was undertaken to investigate the role of protein-energy malnutrition (PEM) as a risk factor for morbidity in patients on long-term hemodialysis. " 10/01/1981 - "The study shows that protein-calorie malnutrition is widespread in stable maintenance hemodialysis patients." 11/01/2009 - "BACKGROUND: Protein-energy malnutrition is a frequently observed problem in hemodialysis patients. " 07/01/2007 - "BACKGROUND: Protein-energy malnutrition occurs commonly in patients receiving hemodialysis (HD). " Order ALL the reference details at left...
4.	Enteral Nutrition (Feeding, Tube) 10/15/1986 - "Enteral nutrition (intensive nutrition counseling and favorite, nutritious foods) is effective in low nutritional risk groups but ineffective in preventing or reversing protein-energy malnutrition in high nutritional risk groups. " 05/01/1995 - "The purpose of this study was evaluate the impact of nocturnal nasogastric tube feeding on diurnal caloric intake in children with severe energy protein-calorie malnutrition. " 01/01/1981 - "Twenty-three adult patients with protein-calorie malnutrition were referred for outpatient tube feeding. " 01/01/2009 - "The meteoric rise in parenteral and enteral nutrition was largely a consequence of the development of total parenteral nutrition and chemically defined diets in the late 1960s and early 1970s and the recognition of the extensive prevalence of protein calorie malnutrition associated with disease in this same period. " 09/30/1990 - "[Parenteral-enteral feeding and monitoring of patients with protein-calorie malnutrition in pharyngeal-laryngeal tumors]" Order ALL the reference details at left...
5.	Aftercare (After-Treatment) 01/01/1975 - "The recurrence and mortality from protein calorie malnutrition after treatment." 07/01/2007 - "METHODS: We previously showed normalized protein catabolic rate (nPCR) to be superior to sAlb to reflect improvement in nutrition status in pediatric patients receiving maintenance HD after treatment with intradialytic parenteral nutrition for severe protein-energy malnutrition. " 08/01/1978 - "Excretion of 3-MeHis was decreased both in children with severe protein-energy malnutrition and during undernutrition and increased considerably after treatment. " 07/01/1976 - "This paper reports a study of changes in red blood cell enzymes and some serum parameters during and after treatment of protein-calorie malnutrition. " 08/01/1978 - "Twenty-four hour urinary excretion of 3-methylhistidine (3-MeHis) was determined in children suffering from severe and moderate degrees of protein-energy malnutrition before and after treatment. " Order ALL the reference details at left...

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