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Protein C

A vitamin-K dependent zymogen present in the blood, which, upon activation by thrombin and thrombomodulin exerts anticoagulant properties by inactivating factors Va and VIIIa at the rate-limiting steps of thrombin formation.
Networked: 4384 relevant articles (150 outcomes, 506 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Griffin, John H: 49 articles (11/2015 - 06/2002)
2. Esmon, Charles T: 41 articles (12/2015 - 01/2002)
3. Levi, Marcel: 34 articles (03/2015 - 06/2003)
4. van der Poll, Tom: 31 articles (11/2015 - 06/2003)
5. Fernández, José A: 24 articles (11/2015 - 06/2002)
6. Zlokovic, Berislav V: 22 articles (01/2015 - 03/2003)
7. Grinnell, Brian W: 21 articles (01/2015 - 12/2002)
8. Rosing, Jan: 21 articles (08/2014 - 07/2002)
9. Matthay, Michael A: 19 articles (07/2010 - 04/2003)
10. Rosendaal, F R: 18 articles (06/2014 - 04/2000)

Related Diseases

1. Sepsis (Septicemia)
2. Septic Shock (Toxic Shock Syndrome)
3. Protein C Deficiency
4. Inflammation
5. Hemorrhage

Related Drugs and Biologics

1. drotrecogin alfa activated (Xigris)
2. Antithrombin III
3. Heparin (Liquaemin)
4. Protein S
5. Dacarbazine (DIC)
6. lipoprotein-associated coagulation inhibitor (TFPI)
7. Anticoagulants
8. Antigens
9. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
10. Norepinephrine (Noradrenaline)

Related Therapies and Procedures

1. Resuscitation
2. Catheters
3. Transplants (Transplant)
4. Artificial Respiration (Mechanical Ventilation)
5. Transplantation (Transplant Recipients)