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Protamines (Protamine Sulfate)

A group of simple proteins that yield basic amino acids on hydrolysis and that occur combined with nucleic acid in the sperm of fish. Protamines contain very few kinds of amino acids. Protamine sulfate combines with heparin to form a stable inactive complex; it is used to neutralize the anticoagulant action of heparin in the treatment of heparin overdose. (From Merck Index, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p692)
Also Known As:
Protamine Sulfate; Protamine Chloride; Chloride, Protamine; Sulfate, Protamine
Networked: 228 relevant articles (5 outcomes, 19 trials/studies)

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Drug Context: Research Results

Experts

1. Frank, Joseph A: 5 articles (04/2011 - 03/2006)
2. Arbab, Ali S: 4 articles (09/2008 - 03/2006)
3. Oliva, Rafael: 3 articles (01/2014 - 07/2006)
4. Rad, Ali M: 3 articles (09/2008 - 08/2007)
5. Voronkova, Ya G: 2 articles (12/2015 - 12/2015)
6. Popova, T N: 2 articles (12/2015 - 12/2015)
7. Agarkov, A A: 2 articles (12/2015 - 12/2015)
8. Sheng, Wang: 2 articles (01/2015 - 12/2013)
9. Zhang, Fang: 2 articles (01/2015 - 12/2013)
10. Cao, Minjun: 2 articles (01/2015 - 12/2013)

Related Diseases

1. Inflammation
2. Thrombocytopenia (Thrombopenia)
3. Thrombosis (Thrombus)
4. Wounds and Injuries (Trauma)
5. Renal Insufficiency (Renal Failure)

Related Drugs and Biologics

1. Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)
2. Cyclophosphamide (Cytoxan)
3. protamine +18RGD
4. Heparin (Liquaemin)
5. DNA (Deoxyribonucleic Acid)
6. Tolonium Chloride
7. Chromatin
8. ferumoxides (Feridex)
9. Insulin (Novolin)
10. Dextrans (Dextran)

Related Therapies and Procedures

1. Cardiopulmonary Bypass (Heart-Lung Bypass)
2. Aftercare (After-Treatment)
3. Catheters
4. Carotid Endarterectomy
5. Vasectomy (Vas Occlusion)