Prostatectomy (Retropubic Prostatectomy)

Complete or partial surgical removal of the prostate. Three primary approaches are commonly employed: suprapubic - removal through an incision above the pubis and through the urinary bladder; retropubic - as for suprapubic but without entering the urinary bladder; and transurethral (TRANSURETHRAL RESECTION OF PROSTATE).

Also Known As:

Networked: 19656 relevant articles (893 outcomes, 2739 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Montorsi, Francesco: 294 articles (10/2022 - 09/2002)
2.	Briganti, Alberto: 285 articles (10/2022 - 02/2004)
3.	Graefen, Markus: 282 articles (10/2022 - 02/2002)
4.	Karakiewicz, Pierre I: 245 articles (10/2022 - 02/2002)
5.	Shariat, Shahrokh F: 170 articles (10/2022 - 02/2002)
6.	Scardino, Peter T: 161 articles (01/2022 - 02/2002)
7.	Epstein, Jonathan I: 160 articles (01/2022 - 01/2002)
8.	Eastham, James A: 158 articles (03/2022 - 03/2002)
9.	Huland, Hartwig: 141 articles (10/2022 - 02/2002)
10.	Freedland, Stephen J: 136 articles (06/2022 - 02/2002)

Related Diseases

1.	Prostatic Neoplasms (Prostate Cancer) 05/01/2021 - "Radical prostatectomy (RP) represents one of the most commonly used first-line treatment modalities in men with localized prostate cancer. " 01/01/2021 - "This perspective review focuses on the most relevant molecules that may have an impact when combined with salvage radiotherapy, and underlines the strategies that need to be developed to increase the efficacy of salvage post-prostatectomy radiotherapy in prostate cancer patients." 01/01/2021 - "Although salvage prostate bed radiotherapy is highly effective in biochemically-relapsing prostate cancer patients following prostatectomy, relapses remain frequent and improvements are needed. " 05/01/2020 - "Radical prostatectomy (RP) represents one of the most commonly used first-line treatment modalities in men with localized prostate cancer (PCa). " 09/01/2018 - "Robot-assisted radical prostatectomy (RP) has gained remarkable worldwide distribution and has become a standard procedure for localised prostate cancer, indeed a new 'gold standard'. "
2.	Neoplasms (Cancer) 06/01/2002 - "Results from a small number of population studies indicate a highly significant improvement in disease-specific survival for radical prostatectomy compared to radiotherapy, and it appears that this difference may become more pronounced as the grade of the cancer increases. " 09/01/1999 - "Radial prostatectomy remains the most effective treatment for organ-confined cancer, yet many patients opt for the opt for the organ-sparing advantage of radiation therapy. " 04/01/2019 - "Over the years the complication rates of radical prostatectomy have become very limited with improved cancer control and better functional results. " 08/01/2016 - "We describe the efficacy of radical prostatectomy to achieve complete primary tumor excision while preserving erectile function in a cohort of patients with high risk features in whom surgical resection was tailored according to clinical staging, biopsy data, preoperative imaging and intraoperative findings. " 04/01/2015 - "The clinical stage of the tumor is an important factor influencing its prognosis and the survival rate of the patients can be improved by early diagnosis and combined therapy dominated by radical prostatectomy."
3.	Urinary Incontinence 01/01/2021 - "To develop and validate a model to predict 12-month continence status after robot-assisted radical prostatectomy (RARP) from preoperative and 3-month postoperative data; this model could help in informing patients on their individualised risk of urinary incontinence (UI) after RP in order to choose the best treatment option. " 12/01/2019 - "Artificial Urinary Sphincter for Postradical Prostatectomy Urinary Incontinence - Is It the Best Option?" 01/01/2022 - "Virtue could be considered an interesting option for postradical prostatectomy urinary incontinence with positive results over time even in patients with high BMI. " 11/25/2020 - "In treating the clinically localized PC, the radical prostatectomy is regarded as a gold standard, but it is associated with syndromes as urinary incontinence (UI), which can have a significant impact on patients' quality of life. " 10/01/2017 - "The majority of patients undergoing the AdVance sling procedure for post-prostatectomy urinary incontinence saw a significant reduction in pad use, and were overall satisfied in both radiated and non-radiated groups at short and long term follow up. "
4.	Erectile Dysfunction 04/01/2009 - "Even 20% of those patients who did not have a nerve preservation got satisfactory erections, Our experience shows that early penile rehabilitation seems to be a good treatment for erectile dysfunction after radical prostatectomy with IPDE5 in fixed doses. " 04/01/1997 - "Nerve-sparing procedures helped reduce the high incidence of impotence that occurs in patients after radical retropubic prostatectomy. " 01/01/2017 - "The pathophysiology of erectile dysfunction post radical prostatectomy is not clearly clarified, and the low efficacy of traditional PDE5i treatment remains a major complaint in contemporary practice. " 11/01/2014 - "Erectile dysfunction (ED) is a major complication after radical prostatectomy (RP); however, debate continues regarding the efficacy of penile rehabilitation in the recovery of the postoperative erectile function (EF). " 02/01/2016 - "To investigate combined therapeutic efficacy of human adipose-derived stem cells (h-ADSCs) application on injured cavernous nerve and low-energy shockwave therapy (SWT) on the corpus cavernosum in a rat model of post-prostatectomy erectile dysfunction. "
5.	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 05/01/2014 - "Robot-assisted simple prostatectomy is a safe and effective operation for benign prostatic hyperplasia, which can be learned with good results in a rather short time." 06/01/2008 - "High power green light laser prostatectomy is a safe and effective method of treating symptomatic benign prostatic hyperplasia in patients with high operative risk." 01/01/1997 - "Free and complexed PSA have different clearances and significant differences between clearance of free PSA after radical prostatectomy (RP) and after open surgery for benign prostatic hyperplasia (BPH) are observed. " 10/01/1990 - "Whilst prostatectomy remains the "gold standard" for the treatment of outflow tract obstruction due to benign prostatic hyperplasia, medical treatment--if only for symptomatic relief--appears to be an attractive alternative. " 05/01/2009 - "We assessed the therapeutic efficacy and safety of laser prostatectomy (LP) for treating benign prostatic hyperplasia (BPH) in patients on oral anticoagulation. "

Related Drugs and Biologics

1.	Androgens
2.	Prostate-Specific Antigen (Semenogelase)
3.	Sildenafil Citrate (Viagra)
4.	Hormones (Hormone)
5.	Opioid Analgesics (Opioids)
6.	Vardenafil Dihydrochloride (Levitra)
7.	Phosphodiesterase 5 Inhibitors
8.	Analgesics (Analgesic Drugs)
9.	Duloxetine Hydrochloride (Cymbalta)
10.	Docetaxel (Taxotere)

Related Therapies and Procedures

1.	Radiotherapy
2.	Therapeutics
3.	Lymph Node Excision (Lymph Node Dissection)
4.	Lasers (Laser)
5.	Transurethral Resection of Prostate (TURP)