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Epoprostenol (Prostacyclin)

Subscribe to Selected New Research on Epoprostenol

4279 relevant articles (308 outcomes, 482 trials/studies) found for this Drug

Description: A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY).

Also Known As:

Prostacyclin; PGI2; Epoprostenol Sodium; Flolan; PGX; Epoprostanol; Epoprostenol Sodium Salt, (5Z,9alpha,11alpha,13E,15S)-Isomer; Prostaglandin I(2); Prostaglandin I2; Prosta-5,13-dien-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, (5Z,9alpha,11alpha,13E,15S)-

Relationship Network

Drug Context: Research Results

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Fatty Acids: 4922

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Unsaturated Fatty Acids: 2398

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Eicosanoids: 1178

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Prostaglandins: 6272

-

Prostaglandins I: 43

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Epoprostenol: 4279

*

*

treprostinil: 84

*

*

*

carboprostacyclin: 17

*

*

*

*

carbaprostacyclin: 8

*

*

*

prostaglandin I3: 7

*

*

19-(3-azidophenyl)-20-norisocarbacyclin: 3

*

9-O-methanoprostaglandin I: 3

*

*

*

*

*

*

*

15-deoxy-(16-m-tolyl)-17,18,19,20-tetranorisocarbacyclin methylester: 1

*

17,20-dimethylisocarbacyclin: 1

*

homoisocarbacyclin: 1

*

naxaprostene: 1

*

prostaglandin I2 methyl ester: 1

*

*

*

*

*

*

*

*

*

10,10-difluoro-13-dehydroprostacyclin

*

11-desoxyprostacyclin

*

13,14-dehydroprostaglandin I2

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13,14-dehydroprostaglandin I2 methyl ester

*

13,14-didehydro-20-methylcarboprostacyclin

*

13,14-dinor-inter-p-phenylene carbacyclin

*

15-cyclopentyl-7-oxo-prostaglandin I2-ephedrine

*

15-deoxy-16-m-tolyl-17,18,19,20-tetranorisocarbacyclin

*

15-fluoro-13,14-dehydrocarbacyclin

*

15-ketoprostaglandin I2

*

16-tolyl-17,18,19,20-tetranorisocarbacyclin

*

2,2,10,10-tetrafluoro-13-dehydroprostacyclin

*

20-methyl-13,14-didehydro-2,4-inter-3-phenylene prostaglandin I2

*

3-oxa-9(O)-methano-delta(6,9)prostaglandin I(1)

*

3-oxacarbacyclin

*

3-oxahomoisocarbacyclin

*

4,5-didehydroisocarbacyclin

*

5,6-dihydroprostacyclin

*

5-hydroxyprostaglandin I

*

5-methyleneisocarbacyclin

*

5-nitroprostaglandin I1

*

5-nitroprostaglandin I2

*

6,9-thiaprostacyclin

*

6a-carbaprostaglandin I3

*

7-fluoroprostacyclin

*

7-oxo-cyclopentyl-prostaglandin I2

*

7-oxo-prostaglandin I2-ephedrine

*

7-oxoprostaglandin I2

*

7a-homo-2-norprostacyclin

*

*

*

*

*

benzodioxane prostacyclin

*

bicyclo(4.3.0)non-2-ene homoisocarbacyclin

*

*

*

*

*

dehydro-15-cyclohexylcarbaprostacyclin

*

dihomo-prostaglandin I(2)

*

*

nitriloprostaglandin I2

*

OP 41483-alpha-cyclodextrin

*

Osaka University cocktail

*

PFC-Kyoto solution

*

prostaglandin I2 11-methyl ether

*

prostaglandin I2 15-methyl ether

*

*

*

*

*

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Arachidonic Acids: 78

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Prostaglandins: 6272

-

Prostaglandins I: 43

-

Epoprostenol: 4279

*

*

treprostinil: 84

*

*

*

carboprostacyclin: 17

*

*

*

*

carbaprostacyclin: 8

*

*

*

prostaglandin I3: 7

*

*

19-(3-azidophenyl)-20-norisocarbacyclin: 3

*

9-O-methanoprostaglandin I: 3

*

*

*

*

*

*

*

15-deoxy-(16-m-tolyl)-17,18,19,20-tetranorisocarbacyclin methylester: 1

*

17,20-dimethylisocarbacyclin: 1

*

homoisocarbacyclin: 1

*

naxaprostene: 1

*

prostaglandin I2 methyl ester: 1

*

*

*

*

*

*

*

*

*

10,10-difluoro-13-dehydroprostacyclin

*

11-desoxyprostacyclin

*

13,14-dehydroprostaglandin I2

*

13,14-dehydroprostaglandin I2 methyl ester

*

13,14-didehydro-20-methylcarboprostacyclin

*

13,14-dinor-inter-p-phenylene carbacyclin

*

15-cyclopentyl-7-oxo-prostaglandin I2-ephedrine

*

15-deoxy-16-m-tolyl-17,18,19,20-tetranorisocarbacyclin

*

15-fluoro-13,14-dehydrocarbacyclin

*

15-ketoprostaglandin I2

*

16-tolyl-17,18,19,20-tetranorisocarbacyclin

*

2,2,10,10-tetrafluoro-13-dehydroprostacyclin

*

20-methyl-13,14-didehydro-2,4-inter-3-phenylene prostaglandin I2

*

3-oxa-9(O)-methano-delta(6,9)prostaglandin I(1)

*

3-oxacarbacyclin

*

3-oxahomoisocarbacyclin

*

4,5-didehydroisocarbacyclin

*

5,6-dihydroprostacyclin

*

5-hydroxyprostaglandin I

*

5-methyleneisocarbacyclin

*

5-nitroprostaglandin I1

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5-nitroprostaglandin I2

*

6,9-thiaprostacyclin

*

6a-carbaprostaglandin I3

*

7-fluoroprostacyclin

*

7-oxo-cyclopentyl-prostaglandin I2

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7-oxo-prostaglandin I2-ephedrine

*

7-oxoprostaglandin I2

*

7a-homo-2-norprostacyclin

*

*

*

*

*

benzodioxane prostacyclin

*

bicyclo(4.3.0)non-2-ene homoisocarbacyclin

*

*

*

*

*

dehydro-15-cyclohexylcarbaprostacyclin

*

dihomo-prostaglandin I(2)

*

*

nitriloprostaglandin I2

*

OP 41483-alpha-cyclodextrin

*

Osaka University cocktail

*

PFC-Kyoto solution

*

prostaglandin I2 11-methyl ether

*

prostaglandin I2 15-methyl ether

*

*

*

*

*

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Biological Factors: 931

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Inflammation Mediators: 506

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-

Eicosanoids: 1178

-

Prostaglandins: 6272

-

Prostaglandins I: 43

-

Epoprostenol: 4279

*

*

treprostinil: 84

*

*

*

carboprostacyclin: 17

*

*

*

*

carbaprostacyclin: 8

*

*

*

prostaglandin I3: 7

*

*

19-(3-azidophenyl)-20-norisocarbacyclin: 3

*

9-O-methanoprostaglandin I: 3

*

*

*

*

*

*

*

15-deoxy-(16-m-tolyl)-17,18,19,20-tetranorisocarbacyclin methylester: 1

*

17,20-dimethylisocarbacyclin: 1

*

homoisocarbacyclin: 1

*

naxaprostene: 1

*

prostaglandin I2 methyl ester: 1

*

*

*

*

*

*

*

*

*

10,10-difluoro-13-dehydroprostacyclin

*

11-desoxyprostacyclin

*

13,14-dehydroprostaglandin I2

*

13,14-dehydroprostaglandin I2 methyl ester

*

13,14-didehydro-20-methylcarboprostacyclin

*

13,14-dinor-inter-p-phenylene carbacyclin

*

15-cyclopentyl-7-oxo-prostaglandin I2-ephedrine

*

15-deoxy-16-m-tolyl-17,18,19,20-tetranorisocarbacyclin

*

15-fluoro-13,14-dehydrocarbacyclin

*

15-ketoprostaglandin I2

*

16-tolyl-17,18,19,20-tetranorisocarbacyclin

*

2,2,10,10-tetrafluoro-13-dehydroprostacyclin

*

20-methyl-13,14-didehydro-2,4-inter-3-phenylene prostaglandin I2

*

3-oxa-9(O)-methano-delta(6,9)prostaglandin I(1)

*

3-oxacarbacyclin

*

3-oxahomoisocarbacyclin

*

4,5-didehydroisocarbacyclin

*

5,6-dihydroprostacyclin

*

5-hydroxyprostaglandin I

*

5-methyleneisocarbacyclin

*

5-nitroprostaglandin I1

*

5-nitroprostaglandin I2

*

6,9-thiaprostacyclin

*

6a-carbaprostaglandin I3

*

7-fluoroprostacyclin

*

7-oxo-cyclopentyl-prostaglandin I2

*

7-oxo-prostaglandin I2-ephedrine

*

7-oxoprostaglandin I2

*

7a-homo-2-norprostacyclin

*

*

*

*

*

benzodioxane prostacyclin

*

bicyclo(4.3.0)non-2-ene homoisocarbacyclin

*

*

*

*

*

dehydro-15-cyclohexylcarbaprostacyclin

*

dihomo-prostaglandin I(2)

*

*

nitriloprostaglandin I2

*

OP 41483-alpha-cyclodextrin

*

Osaka University cocktail

*

PFC-Kyoto solution

*

prostaglandin I2 11-methyl ether

*

prostaglandin I2 15-methyl ether

*

*

*

*

*