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Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)

Enzyme complexes that catalyze the formation of PROSTAGLANDINS from the appropriate unsaturated FATTY ACIDS, molecular OXYGEN, and a reduced acceptor.
Also Known As:
Cyclooxygenase; Cyclo-Oxygenase; Prostaglandin-Endoperoxide Synthase; Arachidonic Acid Cyclooxygenase; Cyclooxygenases; Hydroperoxide Cyclase; PGH2 Synthetase; Prostaglandin Cyclo-Oxygenase; Prostaglandin Cyclooxygenase; Prostaglandin Endoperoxide Synthetase; Prostaglandin G-H Synthase; Prostaglandin H2 Synthetase; Prostaglandin Synthetase; Cyclase, Hydroperoxide; Cyclo Oxygenase; Cyclo-Oxygenase, Fatty Acid; Cyclo-Oxygenase, Prostaglandin; Cyclooxygenase, Arachidonic Acid; Cyclooxygenase, Prostaglandin; Endoperoxide Synthetase, Prostaglandin; Fatty Acid Cyclo Oxygenase; G-H Synthase, Prostaglandin; Prostaglandin Cyclo Oxygenase; Prostaglandin Endoperoxide Synthases; Prostaglandin G H Synthase; Synthase, PGH; Synthase, Prostaglandin; Synthase, Prostaglandin G-H; Synthase, Prostaglandin H; Synthase, Prostaglandin-Endoperoxide; Synthases, Prostaglandin-Endoperoxide; Synthetase, PGH2; Synthetase, Prostaglandin; Synthetase, Prostaglandin Endoperoxide; Synthetase, Prostaglandin H2; Fatty Acid Cyclo-Oxygenase; PGH Synthase; Prostaglandin H Synthase; Prostaglandin Synthase; (5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase
Networked: 6280 relevant articles (188 outcomes, 704 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Konturek, S J: 19 articles (06/2011 - 09/2000)
2. Konturek, P C: 17 articles (11/2006 - 09/2000)
3. Yoshimura, Rikio: 15 articles (04/2009 - 01/2003)
4. DuBois, Raymond N: 14 articles (12/2021 - 05/2003)
5. FitzGerald, Garret A: 14 articles (10/2021 - 04/2002)
6. Matsuyama, Masahide: 14 articles (04/2009 - 11/2003)
7. Brzozowski, T: 13 articles (10/2017 - 10/2000)
8. Basu, Samar: 13 articles (01/2015 - 07/2003)
9. Nair, Muraleedharan G: 13 articles (03/2013 - 01/2003)
10. Kawahito, Yutaka: 13 articles (04/2009 - 11/2003)

Related Diseases

1. Neoplasms (Cancer)
2. Inflammation (Inflammations)
3. Pain (Aches)
4. Carcinogenesis
5. Osteoarthritis

Related Drugs and Biologics

1. Non-Steroidal Anti-Inflammatory Agents (NSAIDs)
2. Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)
3. Prostaglandins
4. Aspirin (Acetylsalicylic Acid)
5. Indomethacin (Indometacin)
6. Lipoxygenase Inhibitors
7. Enzymes
8. Arachidonic Acid (Vitamin F)
9. Protein Isoforms (Isoforms)
10. Dinoprostone (PGE2)

Related Therapies and Procedures

1. Therapeutics
2. Analgesia
3. Secondary Prevention
4. Oral Administration
5. Chemoprevention