HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Complement Factor B (Factor B)

A glycine-rich, heat-labile serum glycoprotein that contains a component of the C3 CONVERTASE ALTERNATE PATHWAY (C3bBb). Bb, a serine protease, is generated when factor B is cleaved by COMPLEMENT FACTOR D into Ba and Bb.
Also Known As:
Factor B; Factor B, Complement; Bb Fragment of Factor B; Complement Factor B Fragment, Bb; Complement Factor B, Alternative Pathway; Complement Factor B-Derived Fragment Bb; Complement Factor Ba; Complement Factor Bb; Complement Protein B; Complement Protein Factor B; Properdin Factor Ba; Properdin Factor Bb; Properdin Factor Bf; Properdin Factor Bf F1; Bb, Complement Factor; Complement Factor B Derived Fragment Bb; Factor B, Properdin; Factor Ba, Complement; Factor Ba, Properdin; Factor Bb, Complement; Factor Bb, Properdin; Factor Bf, Properdin; Proactivator, C3; Proactivator, Complement 3; Protein B, Complement; C3 Proactivator; C3PA; Complement 3 Proactivator; Properdin Factor B
Networked: 700 relevant articles (10 outcomes, 65 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Thurman, Joshua M: 18 articles (01/2020 - 01/2005)
2. Holers, V Michael: 9 articles (07/2013 - 01/2005)
3. Morgan, B Paul: 6 articles (01/2019 - 01/2007)
4. Rodríguez de Córdoba, Santiago: 5 articles (01/2021 - 01/2007)
5. Smith, Richard J H: 5 articles (11/2020 - 05/2010)
6. Chakravarthy, Usha: 5 articles (12/2018 - 02/2009)
7. Atkinson, Carl: 5 articles (11/2012 - 01/2010)
8. López-Trascasa, Margarita: 4 articles (01/2021 - 01/2007)
9. Kirschfink, Michael: 4 articles (10/2019 - 12/2010)
10. Pekna, Marcela: 4 articles (01/2017 - 04/2004)

Related Diseases

1. Lymphoma (Lymphomas)
2. Demyelinating Diseases (Demyelinating Disease)
3. Macular Degeneration (Age-Related Maculopathy)
4. Acute-Phase Reaction
5. Proteinuria

Related Drugs and Biologics

1. Proteins (Proteins, Gene)
2. Complement System Proteins (Complement)
3. Messenger RNA (mRNA)
4. Antigen-Antibody Complex (Immune Complex)
5. Small Interfering RNA (siRNA)
6. Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)
7. P-Selectin
8. Antisense Oligonucleotides
9. Steroids
10. Complement Factor H (Factor H)

Related Therapies and Procedures

1. Therapeutics
2. Punctures
3. Percutaneous Collagen Induction
4. Lasers (Laser)
5. Aftercare (After-Treatment)