Propafenone (Rythmol)

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608 relevant articles (134 outcomes, 118 trials/studies) found for this Drug

Description: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity. The drug is generally well tolerated.

Also Known As:

Rythmol; SA 79; Abbott Brand of Propafenone Hydrochloride; Aliud Brand of Propafenone Hydrochloride; Alpharma Brand of Propafenone Hydrochloride; Apo-Propafenone; Apotex Brand of Propafenone Hydrochloride; Arythmol; Azupharma Brand of Propafenone Hydrochloride; Baxarytmon; Cuxafenon; Fenoprain; Hexal Brand of Propafenone; Juta Brand of Propafenone Hydrochloride; Jutanorm; Kendrick Brand of Propafenone Hydrochloride; Knoll Brand of Propafenone Hydrochloride; Merck dura Brand of Propafenone Hydrochloride; Nistaken; Norfenon; Pintoform; Prolecofen; Propafenon AL; Propafenon Hexal; Propafenon Minden; Propafenone Hydrochloride; Propafenone Hydrochloride, (R)-Isomer; Propafenone Hydrochloride, (S)-Isomer; Propafenone, (+-)-Isomer; Propafenone, (R)-Isomer; Propafenone, (S)-Isomer; Propamerck; Q-Pharm Brand of Propafenone Hydrochloride; Rytmo-Puren; Rytmogenat; Rytmonorm; SA-79; TAD Brand of Propafenone Hydrochloride; Hydrochloride, Propafenone; SA79; 1-Propanone, 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-

Relationship Network

Drug Context: Research Results

Organic Chemicals: 40

5-hydroxypropafenone: 3

LG 6-101: 2

LG 6-102: 2

5-hydroxy-4-methoxypropafenone

5-hydroxydiprafenone

butafenone

N-depropylpropafenone

SA 76

Experts

1.	Vardas, Panos E: 3 articles (06/2007 - 02/2004)
2.	Igoumenidis, Nikos E: 3 articles (06/2007 - 02/2004)
3.	Kochiadakis, George E: 3 articles (06/2007 - 02/2004)
4.	Hofmann, U: 2 articles (07/2008 - 06/2000)
5.	Eichelbaum, M: 2 articles (07/2008 - 06/2000)
6.	Hamilos, Michail E: 2 articles (06/2007 - 12/2004)
7.	Chlouverakis, Gregory I: 2 articles (06/2007 - 12/2004)
8.	Fragakis, Nikolaos: 2 articles (06/2007 - 09/2005)
9.	Papanastasiou, Soultana: 2 articles (06/2007 - 09/2005)
10.	Katsaris, George: 2 articles (06/2007 - 09/2005)

Related Diseases

1.	Atrial Fibrillation 06/01/1987 - "Furthermore, propafenone caused a marked decrease in peak ventricular rate during atrial fibrillation" 03/01/1996 - "Furthermore, the percentage decrease of ventricular rate during atrial fibrillation was significantly greater in patients with propafenone (-25 +/- 4% versus -8 +/- 3%, P < 0.01)" 12/15/2002 - "We report a double-blind, multicenter, multinational, placebo-controlled, and well-controlled trial to prove that the sustained-release (SR) formulation of propafenone is superior to placebo in preventing symptoms of paroxysmal atrial fibrillation (AF)" 03/01/2000 - "Propafenone is an effective and safe antiarrhythmic drug for converting paroxysmal and/or recent-onset atrial fibrillation of various origins with a more limited efficacy in chronic atrial fibrillation." 01/03/1997 - "Propafenone acute oral administration is more effective than placebo in rapidly converting recent-onset atrial fibrillation to sinus rhythm and may be the treatment of choice in this setting limiting hospitalization and contributing to improved quality of life." Order ALL the reference details at left...
2.	Tachycardia (Tachyarrhythmias) 01/01/1995 - "Propafenone is a potent antiarrhythmic agent effective in either supraventricular or ventricular tachyarrhythmias" 04/01/1990 - "Seven of the 13 children (53.8%) with ventricular ectopics, all three children with paroxysmal re-entry atrioventricular tachycardia, and two of the three children with paroxysmal atrial tachycardia were treated successfully with propafenone" 07/01/1991 - "Acute and long-term efficacy of propafenone in patients with sustained ventricular tachyarrhythmias: assessment with programmed ventricular stimulation." 08/01/1995 - "Although propafenone is effective in the acute management of junctional reentrant tachycardias, the availability of safer drugs precludes its routine use for these arrhythmias" 09/15/1991 - "Propafenone was partially or completely effective in 3 of 4 patients with chaotic atrial tachycardia" Order ALL the reference details at left...
3.	Cardiac Arrhythmias (Arrythmia) 06/01/1992 - "CONCLUSIONS--A younger age, low spontaneous arrhythmia variability, and particularly a low titration dose were the best predictors of the short and long term efficacy of propafenone" 12/15/2002 - "There was a significant reduction in average heart rate during the first recurrence of symptomatic arrhythmia after day 5 in the low-dose propafenone group compared with placebo" 08/01/1987 - "In junctional arrhythmia propafenone was certainly effective but unpredictably so (3 good results, 2 fair results, 4 failures)" 11/01/2002 - "Elevated plasma concentration is consistent with better efficacy of propafenone in patients with ventricular arrhythmia." 06/01/1987 - "Electrophysiologic testing identified the patient's arrhythmia, and demonstrated that it improved with intravenous propafenone, a new type 1C antiarrhythmic medication" Order ALL the reference details at left...
4.	Ventricular Tachycardia 03/01/1986 - "In 19 cases of ventricular tachycardia, propafenone proved to be efficacious in 3 out of 5 cases presenting rapid discharges and in 7 out of 14 patients with continuous arrhythmias, notably those with a catecholaminergic component" 12/01/1988 - "Propafenone is effective in treating ventricular tachycardia and in suppressing premature ventricular complexes (PVCs)" 11/14/1984 - "Propafenone was also effective in controlling couplets and nonsustained ventricular tachycardia" 11/01/1990 - "Efficacy of propafenone in preventing ventricular tachycardia: inverse correlation with rate-related prolongation of conduction time." 10/01/1985 - "Propafenone eliminated all exercise provocable ventricular tachycardia" Order ALL the reference details at left...
5.	Atrial Flutter (Flutter, Atrial) 12/15/1995 - "Thirty patients with type I atrial flutter were randomized into 2 groups in which transesophageal pacing was attempted: group A, without treatment; and group B, after oral administration of propafenone 600 mg. Transesophageal pacing was effective in interrupting atrial flutter in 53% of patients (8 of 15) in group A and in 87% of patients (13 of 15) in group B" 09/15/1991 - "Propafenone was effective in 33 of 37 patients (89%); atrial flutter was controlled in 2 patients, ventricular ectopy was suppressed in 1 of 2 patients" 08/01/1991 - "Propafenone is effective in greater than 50% of patients with paroxysmal atrial flutter or fibrillation, resistant to other antiarrhythmic agents" 02/01/1996 - "We can conclude that propafenone is effective and safe when used with transesophageal pacing in the termination of atrial flutter" 12/15/1995 - "We conclude that propafenone is effective and safe when used with transesophageal pacing in the termination of atrial flutter" Order ALL the reference details at left...

Related Drugs and Biologics

1.	Flecainide (Tambocor)
2.	Amiodarone (Amiodarona)
3.	Sotalol (Sotalol Hydrochloride)
4.	Quinidine (Chinidin)
5.	Disopyramide (Norpace)
6.	Procainamide (Procan)
7.	ibutilide (Corvert)
8.	Mexiletine (Mexitil)
9.	Digoxin (Digitek)
10.	Cytochrome P-450 CYP2D6 (CYP2D6)

Related Therapies and Procedures

1.	Electric Countershock (Cardioversion)
2.	Fontan Procedure (Fontan Operation)
3.	Hemoperfusion
4.	Bed Rest (Bedrest)
5.	Implantable Defibrillators (Implantable Cardioverter-Defibrillator)

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