|1.||Phang, James M: 9 articles (11/2012 - 08/2005)|
|2.||Liu, Wei: 6 articles (11/2012 - 08/2010)|
|3.||Liu, Yongmin: 3 articles (08/2009 - 08/2005)|
|4.||Palka, Jerzy: 2 articles (01/2015 - 01/2015)|
|5.||Kononczuk, Joanna: 2 articles (01/2015 - 01/2015)|
|6.||Miltyk, Wojciech: 2 articles (01/2015 - 01/2015)|
|7.||Czyzewska, Urszula: 2 articles (01/2015 - 01/2015)|
|8.||Surazynski, Arkadiusz: 2 articles (01/2015 - 08/2005)|
|9.||Nadrich, Robert H: 2 articles (06/2014 - 09/2011)|
|10.||Clelland, Catherine L: 2 articles (06/2014 - 09/2011)|
02/01/1977 - "Attempts to show that catabolite repression of proline oxidase synthesis could be relieved during NH4+ starvation also failed. "
01/01/2014 - "In particular, nutrient starvation elicits increased activity of mitochondrial proline oxidase/dehydrogenase (POX/PRODH) that is causal in triggering a ROS-dependent induction of ATGL. "
01/01/2011 - "Whereas chromatin immunoprecipitation analyses confirm the direct binding of bZIP1 and bZIP53 to promoters of key metabolic genes, such as ASPARAGINE SYNTHETASE1 and PROLINE DEHYDROGENASE, the G-box, C-box, or ACT motifs (ACTCAT) have been defined as regulatory cis-elements in the starvation response. "
|2.||Schizophrenia (Dementia Praecox)
01/01/2015 - "Previous studies have suggested that an association exists between the proline dehydrogenase gene (PRODH) and increased schizophrenia risk. "
03/06/2003 - "A family-based association study of T1945C polymorphism in the proline dehydrogenase gene and schizophrenia in the Chinese population."
01/01/2015 - "Relationship between polymorphisms in the proline dehydrogenase gene and schizophrenia risk."
03/01/2012 - "We also consider other risk-associated genes for schizophrenia such as dysbindin (DTNBP1), neuregulin (NRG1), disrupted-in-schizophrenia1 (DISC1), reelin and proline dehydrogenase (PRODH). "
09/01/2011 - "There are multiple genetic links between schizophrenia and a deficit of proline dehydrogenase (PRODH) enzyme activity. "
|3.||Breast Neoplasms (Breast Cancer)
01/01/2014 - "Amongst six cancer cell lines, ZR75-30 human breast cancer cells had the highest basal proline dehydrogenase levels, and mitochondria isolated from ZR75-30 cells consumed oxygen and produced H2O2 with proline as sole substrate. "
01/01/2015 - "This study presents effects of two αIIbβ3-inhibitors: Abciximab and Eptifibatide on apoptosis, expression of proline oxidase (POX), signaling molecules ERK 1/2, transcription factor NF-κB and HIF-1α, vascular endothelial growth factor (VEGF) as well as DNA biosynthesis, collagen biosynthesis and prolidase activity in MCF-7 breast cancer cells. "
|4.||Mood Disorders (Mood Disorder)
09/01/2005 - "This is the first study on a potential involvement of the proline dehydrogenase locus in bipolar affective disorder. "
09/01/2005 - "In addition, we assessed whether proline dehydrogenase also contributes to bipolar affective disorder, because chromosome 22q11 is also implicated in bipolar affective disorder. "
09/01/2005 - "Neither single marker nor haplotype analysis revealed an association between variants at the proline dehydrogenase locus and schizophrenia or bipolar affective disorder."
09/01/2005 - "No evidence for an association between variants at the proline dehydrogenase locus and schizophrenia or bipolar affective disorder."
01/01/2015 - "Proline Oxidase (POX) as A Target for Cancer Therapy."
01/01/2014 - "Proline dehydrogenase is proposed to generate radicals that contribute to cancer cell apoptosis. "
07/15/2012 - "Proline oxidase promotes tumor cell survival in hypoxic tumor microenvironments."
01/01/2012 - "proline dehydrogenase (PRODH), is among a few genes induced rapidly and robustly by P53, the tumor suppressor. "
08/21/2010 - "These effects of proline oxidase, as well as its decreased levels in tumors, support its role as a tumor suppressor. "
|1.||Catechol O-Methyltransferase (Methyltransferase, Catechol)
|2.||Neuregulin-1 (Neuregulin 1)
|3.||GTP-Binding Proteins (G-Protein)
|6.||Phospholipases A2 (Phospholipase A2)
|7.||Cannabinoid Receptors (Cannabinoid Receptor)
|8.||Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
|9.||Brain-Derived Neurotrophic Factor (BDNF)
|10.||sigma Receptors (sigma Receptor)