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Procollagen N-Endopeptidase (Procollagen Peptidase)

An extracellular endopeptidase which excises a block of peptides at the amino terminal, nonhelical region of the procollagen molecule with the formation of collagen. Absence or deficiency of the enzyme causes accumulation of procollagen which results in the inherited connective tissue disorder--dermatosparaxis. EC 3.4.24.14.
Also Known As:
Procollagen Peptidase; Procollagen N-Proteinase; Procollagen N Endopeptidase; Procollagen N Proteinase
Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Prockop, D J: 1 article (04/2001)
2. Hyttinen, M M: 1 article (04/2001)
3. Helminen, H J: 1 article (04/2001)
4. Arita, M: 1 article (04/2001)
5. Kopen, G C: 1 article (04/2001)
6. Långsjö, T K: 1 article (04/2001)
7. Fertala, A: 1 article (04/2001)
8. Bao, Y: 1 article (04/2001)
9. Li, S W: 1 article (04/2001)
10. Tang, B L: 1 article (01/2001)

Related Diseases

1. Ehlers-Danlos Syndrome (Syndrome, Ehlers-Danlos)
2. Osteogenesis Imperfecta (Lobstein Disease)
3. Lathyrism
4. Male Infertility (Male Sterility)
5. Connective Tissue Diseases (Connective Tissue Disease)

Related Drugs and Biologics

1. Collagen Type I (Type I Collagen)
2. Serine (L-Serine)
3. Oxidoreductases
4. 2-Oxoglutarate 5-Dioxygenase Procollagen-Lysine (Lysyl Hydroxylase)
5. Lysine (L-Lysine)
6. Glycine (Aminoacetic Acid)
7. Collagen