Polyuria

09/02/2019 - "As the only licensed product for all adults including those over 65 years of age, low dose desmopressin (Noqdirna® (as lyophilisate) Ferring Pharmaceuticals Ltd) is highly effective in the management of idiopathic nocturnal polyuria, producing improvements in clinical symptoms, sleep parameters and quality of life. "
08/15/2008 - "Desmopressin is most effective in children with nocturnal polyuria and normal bladder capacity. "
10/01/2020 - "Desmopressin has proven to be an effective and well-tolerated treatment in patients with nocturnal polyuria. "
04/01/2021 - "Administration of DDAVP in post-KT recipients with mild polyuria and subclinical CDI is difficult to assess, and whether long-term use of DDAVP is beneficial for the transplanted kidney has not been established. "
11/09/2019 - "A high level of evidence supports the efficacy of desmopressin in the treatment of nocturnal polyuria. "

01/01/2020 - "These results provide evidence supporting sodium restriction as an effective treatment for nocturnal polyuria."
01/01/2020 - "this study compares diuresis rate, sodium clearance and free water clearance (FWC) by age and time of day (nighttime vs. daytime) in subjects with and without nocturnal polyuria (NP) to determine whether these variables affect the phenotype of NP. "
01/01/2018 - "But they probably also increase the risk of rapid serum sodium correction - most commonly defined as > 12 mmol/L/d (moderate certainty evidence due to indirectness) (14 studies, 2058 participants: RR 1.67, 95% CI 1.16 to 2.40) and commonly cause side-effects such as thirst (13 studies, 1666 participants: OR 2.77, 95% CI 1.80 to 4.27) and polyuria (6 studies, 1272 participants): RR 4.69, 95% CI 1.59 to 13.85) (high certainty evidence). "
03/01/2016 - "This study aimed to identify important differences in renal function profile, and potential water and sodium diuresis cutoffs among participants with nocturnal polyuria according to nocturnal polyuria definitions. "
11/15/2023 - "DI was diagnosed by polyuria, low urine specific gravity, and increasing serum sodium, measured in close proximity. "

01/01/1991 - "A polyuria and a decreased creatinine clearance are reported on day 8. We were interested in a special study of this polyuria. "
01/01/2019 - "When compared to the HD group, patients treated with CVVH/HD or SLED/HD required a shorter period of time to enter into polyuria stage [(24.7 ± 4.3) days vs (20.2 ± 4.7) days vs (18.2 ± 3.0) days, F = 9.11, p = 0.0007], and required a shorter time for serum creatinine to return to normal [(45.7 ± 13.4) days vs (33.1 ± 9.4) days vs (31.9 ± 9.8), F = 5.83, p = 0.0069]; while such parameters had no significant differences between SLED/HD group and CVVH/HD group. "
01/01/2017 - "Controls with nocturnal polyuria had no circadian rhythms in the diuresis rate or creatinine clearance and a significant increase in nocturnal free water clearance compared to daytime levels. "
12/01/2015 - "The most common side effect of polyuria only weakly predicts increasing creatinine or reduced kidney function. "
04/17/2013 - "After 6 weeks of standard antituberculous treatment, progressive deterioration of his renal function was observed: creatinine levels rose from 38.9μmol/L to 318.2μmol/L and urine volume also progressively increased to reach a state of true polyuria (8 to 10L of urine per day). "

03/01/2006 - "Empiric treatment with vasopressin improved the polyuria. "
11/15/2004 - "The studies described in this PhD Thesis, which was defended in January 2004 in Utrecht, investigated the role of the antidiuretic hormone vasopressin (VP) in the pathogenesis of different forms of canine polyuria. "
01/01/1997 - "Studies in Brattle Boro rats which are vasopressin deficient, revealed low levels of AQP2 in association with extreme polyuria. "
12/01/2022 - "After admission, to examine the cause of his thirst and polyuria, we performed a water restriction test, vasopressin loading test, hypertonic saline loading test and pituitary magnetic resonance imaging. "
07/01/2022 - "Of the individuals, 21% displayed polyuria (>3 l/d), but 55% displayed elevated fasting vasopressin level (>5 pg/ml). "

02/01/2001 - "During polyuria, the significant increase in arterial pressure was significantly different from the not significant effect in salt depletion; the not significant effect on saluresis was significantly different from the significant reduction in salt depletion. "
01/01/2023 - "Cerebral salt wasting should be considered in the initial differential diagnosis of a patient presenting with polyuria in the context of acute neurological injury. "
01/01/2023 - "In this case report, we described an exceptional case of polyuria attributed to an initial cerebral salt wasting phenomenon and iatrogenic-induced medullary washout. "
03/01/2022 - "Dahl salt-sensitive rats fed a 2% salt diet were candidates for a model of nocturnal polyuria. "
01/01/2022 - "Reduced renal function impairs salt and water homeostasis, which can drive nocturnal or 24-h polyuria. "

02/01/2015 - "This study aimed to establish independent risk factors for polyuria in a community, secondary-level lithium-treated sample of patients. "
10/01/2013 - "The available evidence is contradictory as to whether SDD of lithium reduces polyuria; however, no trial has demonstrated any downfall of SDD in terms of prophylactic efficacy or adverse effects. "
06/01/2011 - "Distress due to lithium-induced polyuria: exploratory study."
03/01/1983 - "The mechanism of polyuria in rats pretreated with lithium studies by in vitro microperfusion."
11/16/2023 - "The duration of lithium may be the most important risk factor for lithium-induced polyuria. "

01/01/2022 - "If the symptoms of diabetes have been known since Antiquity, it is at the end of the 19th century that several investigators searched for the active substance of the pancreas and endeavoured to produce extracts that lowered blood and urine glucose and decreased polyuria in pancreatectomized dogs. "
01/01/2020 - "The glucose that remains in renal tubules was proposed to produce an osmotic effect resulting in polyuria. "
11/07/2014 - "SAMP10/TaSlc mice consumed increasing amounts of food and water compared to SAMR1/TaSlc mice, suggesting the compensation of polyuria and the loss of glucose. "
06/01/2002 - "After a 2-h blood perfusion, five of the seven CPA-perfused kidneys developed polyuria (0.21 mlxmin(-1)xg(-1)) relative to untreated controls (0.07 mlxmin(-1)xg(-1)) or EC-perfused kidneys (0.06 mlxmin(-1)xg(-1)), owing to the lower reabsorption of water (34.3%), Na(+) (34.2%) and glucose (35.6%). "
04/23/1999 - "Diagnosis of diabetes is not in doubt when there are classical symptoms of thirst and polyuria and a random venous plasma glucose level > or =11.1 mmol/L. "

08/05/2020 - "This study aims to explore the association between nocturnal polyuria (NP) and urea. "
01/01/2019 - "Water deprivation revealed persisting polyuria, impaired urinary concentration ability, and augmented urinary excretion of Na+ and urea in both mutant mice. "
01/01/2012 - "In the kidney, deletion of UT-A1/UT-A3 results in polyuria and a severe urine concentrating defect, indicating that intrarenal recycling of urea plays a crucial role in the overall capacity to concentrate urine. "
09/01/1991 - "A water deprivation test was conducted on three animals: polyuria disappeared and plasma urea increased significantly."
07/01/1995 - "On hospital day 2, went into coma with high temperature, diaphoresis, polyuria, leucocytosis (WBC count 15,440 U/mm3), urea 7 mg/dl, LDH 425 U/l, Na 114 mEq/l, K 2.5 mEq/l. "

11/01/2021 - "Mice subjected to 14 days of potassium-deficient diet developed polyuria and AQP2 downregulation in IM. "
10/01/2000 - "Early polyuria and urinary concentrating defect in potassium deprivation."
01/01/1982 - "The kidneys also exhibited isosthenuric polyuria with a reduced potassium secretion. "
09/01/1977 - "The association of potassium (K) depletion with polyuria and a concentrating defect is established, but the extent to which these defects could be secondary to an effect of low K on water intake has not been systematically investigated. "
09/01/1977 - "On the mechanism of polyuria in potassium depletion. "

06/01/2014 - "Both children were treated with indomethacin resulting in improved linear growth and polyuria. "
02/01/2001 - "During polyuria significant positive correlations occurred between the absolute effects of indomethacin on 6KPGF excretion and those on functional excretory parameters. "
07/01/1990 - "By reducing urine output, indomethacin controlled both in utero and extrauterine polyuria in this patient."
12/01/1989 - "II. Indomethacin and effects of lysine-8-vasopressin in hypotonic polyuria]."
11/01/1989 - "Later an additional treatment with indomethacin (2 mg/kg/d) was necessary in 3 boys because of an increase of polyuria; there was a further reduction of the daily urinary volume of 50-60%. "

01/01/2022 - "Does hormonal therapy affect the bladder or the kidney in postmenopausal women with and without nocturnal polyuria: Results of a pilot trial?"
01/01/2022 - "Under this therapy, polyuria reduced to 3-3.5 liters per a day. "
01/01/2022 - "The affectivity of the combination therapy was very high with least side effects for the treatment of OAB/nocturnal polyuria."
01/01/2021 - "This narrative review synthesizes current evidence on the medical management of nocturnal polyuria, including antidiuretic replacement therapy as well as other emerging modalities, with particular emphasis on areas of active investigation and future research directions. "
03/01/2009 - "At baseline, all except for 1 patient had nocturnal polyuria (nocturnal polyuria index > 33%), and, after the combination therapy, the nocturnal polyuria had resolved in 6 (11.5%) of the 52 patients with nocturnal polyuria at baseline. "

04/01/1986 - "As a teenager she no longer had thirst or polyuria after treatment was stopped. "
04/12/2022 - "Twelve months after treatment, we observed an increase of grade 1−2 dysuria (46% vs. 13% before treatment) and grade 1 polyuria (73% vs. 7%). "
01/01/2021 - "The frequency of nocturnal urination, volume of nocturnal urine, time from falling asleep to first urination, first urinary volume after falling asleep, nocturnal polyuria index, International Prostate Symptom Score (IPSS), quality of life index, Overactive Bladder Symptom Score, and residual urine volume were comparatively evaluated before and 4 weeks after treatment. "
03/01/2019 - "The hypernatremia with polyuria persisted for 16 days and resolved after treatment of the positive cumulative water balance (with controlled diuresis prioritizing natriuresis). "
06/01/2003 - "Polyuria and/or polydipsia, present in 11 horses, was reduced in all after treatment. "

11/01/2010 - "The purpose of this study was to elucidate the prevalence of nocturnal polyuria among renal transplant recipients in the early period after transplantation as well as at least 1 year after transplantation. "
08/01/2021 - "Polyuria after transplantation was seen in 63% of patients, mainly in the first post-transplant years and recipients aged <10 years. "
01/01/2017 - "Does the Age of Donor Kidneys Affect Nocturnal Polyuria in Patients With Successful Real Transplantation?"
05/01/2006 - "Urodynamic evaluation prior to transplantation showed decreased bladder sensation and increased bladder capacity, probably because of congenital polyuria. "
06/01/2006 - "Polyuria is not considered an absolute indication for pre-transplant nephrectomy; however, it may complicate post-transplantation fluid management. "

02/01/2007 - "Because the study population exhibited a poor glycemic control (HbA1c 10.2+/-2.4 %), an influence of glucosuria-induced polyuria on BV cannot be excluded. "
12/31/2022 - "However, 5 years later (at 75 years of age), she re-exhibited thirst, polydipsia, and polyuria despite stable glycemic control. "
01/01/2021 - "Three diabetic cats presented with polyuria, polydipsia, polyphagia and poor glycemic control. "
01/01/2015 - "Collectively, our findings suggest that daily, short duration WBV may improve glycemic control, polydipsia, polyuria, and urine osmolality in T2DM in association with reduced inflammation. "
10/01/2004 - "It should be considered in a diabetic patient with unexplained optic atrophy, hearing loss, or polyuria and polydipsia in the presence of adequate blood glucose control. "

06/01/2009 - "The case highlights the dangers of massive fluid therapy in the context of polyuria and, therefore, the need for intensive monitoring."
04/01/2022 - "When fluid therapy is unsuccessful in improving urine production, various drugs treatments have been used in an attempt to increase urine production, but none are consistently effective in converting oliguria to polyuria."
10/01/2016 - "The discrepancy between the frequency of cats with polyuria and PODFR (87.7% vs 36.8%) in the present study indicates that administered intravenous fluid therapy might be the driving force for the high incidence of polyuria in some cats with naturally occurring obstructive feline lower urinary tract disease."
08/17/2016 - "Polyuria/polydipsia, dehydration, prednisolone or furosemide pretreatment, azotemia and diabetes mellitus increased, whereas fluid therapy and the diagnosis of neoplasia decreased the prevalence of hypochloremia. "