RNA Ligase (ATP) (tRNA Ligase)
An enzyme that catalyzes the conversion of linear RNA to a circular form by the transfer of the 5'-phosphate to the 3'-hydroxyl terminus. It also catalyzes the covalent joining of two polyribonucleotides in phosphodiester linkage. EC 6.5.1.3.
Also Known As:
tRNA Ligase; Ligase, tRNA; Synthetase, Polyribonucleotide; Polyribonucleotide Synthetase; Poly(ribonucleotide):poly(ribonucleotide)ligase (AMP-forming)
Networked: 3
relevant articles (0 outcomes,
0 trials/studies)
Bio-Agent Context: Research Results
Experts
| 1. | Boos, Drake:
1 article
(11/2022)
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| 2. | Chuang, Tsai-Der:
1 article
(11/2022)
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| 3. | Khorram, Omid:
1 article
(11/2022)
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| 4. | Quintanilla, Derek:
1 article
(11/2022)
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| 5. | Andrejeva, Anna:
1 article
(01/2021)
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| 6. | Bartenschlager, Ralf:
1 article
(01/2021)
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| 7. | Castello, Alfredo:
1 article
(01/2021)
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| 8. | Cerikan, Berati:
1 article
(01/2021)
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| 9. | Chen, Honglin:
1 article
(01/2021)
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| 10. | Cortese, Mirko:
1 article
(01/2021)
|
Related Diseases
| 1. | Neoplasms (Cancer)
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| 2. | Leiomyoma (Uterine Fibroids)
11/01/2022
- " In fibroids, the expression of tryptophan hydroxylase 1 (TPH1), kynurenine amino transferase (KAT)2, large neutral amino acid transporter small subunit 2 (SLC7A8), and large neutral amino acid transporter small subunit 1 (SLC7A5) messenger RNA (mRNA) was high and that of kynureninase (KYNU) and tryptophanyl-tRNA ligase (WARS1) mRNA was low, with no changes in the expression of WARS2, kynurenine formamidase (AFMID), kynurenine 3-monooxygenase (KMO), KAT1, KAT3, and KAT4 compared with that in the matched myometrium (n = 81). "
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| 3. | COVID-19
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