Polymyalgia Rheumatica (Rhizomelic Pseudopolyarthritis)

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402 relevant articles (20 outcomes, 31 trials/studies) found for this Disease

Description: A syndrome in the elderly characterized by proximal joint and muscle pain, high erythrocyte sedimentation rate, and a self-limiting course. Pain is usually accompanied by evidence of an inflammatory reaction. Women are affected twice as commonly as men and Caucasians more frequently than other groups. The condition is frequently associated with GIANT CELL ARTERITIS and some theories pose the possibility that the two diseases arise from a single etiology or even that they are the same entity.

Also Known As:

Rhizomelic Pseudopolyarthritis; Forestier Certonciny Syndrome; Peri-Extra-Articular Rheumatism; Pseudopolyarthritides, Rhizomelic; Rheumatism, Peri Extra Articular; Rhizomelic Pseudopolyarthritides; Syndrome, Forestier-Certonciny; Forestier-Certonciny Syndrome; Pseudopolyarthritis, Rhizomelic; Rheumatism, Peri-Extra-Articular

Relationship Network

Disease Context: Research Results

Musculoskeletal Diseases: 83

Rheumatic Diseases: 4792

Polymyalgia Rheumatica: 402

Muscular Diseases: 4140

Polymyalgia Rheumatica: 402

Skin and Connective Tissue Diseases

Connective Tissue Diseases: 1633

Rheumatic Diseases: 4792

Polymyalgia Rheumatica: 402

Related Diseases

1.	Giant Cell Arteritis (Horton Disease)
2.	Rheumatoid Arthritis
3.	Syndrome
4.	Osteoporosis
5.	Vasculitis (Vasculitides)

Experts

1.	Salvarani, Carlo: 8 articles (08/2008 - 04/2003)
2.	Salvarani, C: 8 articles (05/2008 - 05/2000)
3.	Boiardi, Luigi: 6 articles (08/2008 - 04/2003)
4.	Macchioni, Pierluigi: 5 articles (08/2008 - 04/2003)
5.	Cantini, Fabrizio: 5 articles (08/2008 - 04/2003)
6.	Catanoso, Maria Grazia: 5 articles (12/2007 - 04/2003)
7.	Boiardi, L: 5 articles (11/2000 - 05/2000)
8.	Pulsatelli, Lia: 4 articles (08/2008 - 04/2003)
9.	Macchioni, P: 4 articles (05/2008 - 05/2000)
10.	Silvestri, T: 4 articles (09/2006 - 09/2000)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Polymyalgia Rheumatica:

1.	Prednisone (Sone)FDA LinkGeneric 11/01/2008 - "Under a working diagnosis of polymyalgia rheumatica (PMR) her prednisone dose was increased, leading to a complete remission.; her symptoms resolved and the ESR normalized" 10/01/2007 - "Twelve subjects with inactive polymyalgia rheumatica receiving chronic (>12 months) prednisone (mean = 5.0 +/- 0.8 mg/d) were compared with 12 age- and gender-matched normal subjects" 11/01/2005 - "She was relapse-free of polymyalgia rheumatica after discontinuation of prednisone on the 50th postoperative day" 07/25/1998 - "In the year before the current admission she developed myalgias and was treated for polymyalgia rheumatica with low-dose prednisone" 02/01/1977 - "A 70-year-old woman presenting with typical polymyalgia rheumatica (PMR) and a normal temporal artery biopsy appeared to respond completely to low-dose prednisone therapy" Order ALL the reference details at left...
2.	SteroidsIBA 11/08/2006 - "A 81-year-old patient with a six month history of upper extremity tenderness, most likely due to an atypical presentation of a polymyalgia rheumatica, responded well to a course of systemic steroids" 05/01/2007 - "BACKGROUND: A reliable alternative to steroids for treating polymyalgia rheumatica has not yet been identified" 11/01/2005 - "Low-dose steroids given for a suspected polymyalgia rheumatica caused only minimal and transient improvement" 08/01/2005 - "Before admission, she was treated by steroids for polymyalgia rheumatica" 10/05/2004 - "BACKGROUND: Steroids are the standard treatment for polymyalgia rheumatica" Order ALL the reference details at left...
3.	Adrenal Cortex Hormones (Corticosteroids)IBA 11/21/2008 - "Moreover, due to polymyalgia rheumatica the patient received corticosteroids as treatment for the last 3 years" 02/01/2008 - "Treatment with corticosteroids reduces arterial stiffness in patients with polymyalgia rheumatica as measured with pulse wave analysis." 10/01/2005 - "II. Polymyalgia rheumatica: behaviour of lymphocyte subpopulations during treatment with two different corticosteroids]" 07/01/2000 - "Corticosteroids in polymyalgia rheumatica--a review of different treatment schedules." 03/22/1999 - "CONCLUSIONS: Polymyalgia rheumatica is a heterogeneous disease with variations in the treatment duration and dose of corticosteroids required for suppression of symptoms" Order ALL the reference details at left...
4.	C-Reactive ProteinIBA 09/17/2006 - "It should be noted, that polymyalgia rheumatica may also be present if the erythrocyte sedimentation rate and C-reactive protein values are low" 07/01/2004 - "In active polymyalgia rheumatica, FDG uptake was significantly correlated with C reactive protein (r = 0.8), ESR (r = 0.79), and platelet counts (r = 0.68)" 08/15/2001 - "The presence of constitutional symptoms (OR = 0.14; 95% CI: 0.02 to 0.77, P = 0.01), polymyalgia rheumatica (OR = 0.04; 95% CI: 0.01 to 0.48, P = 0.02), and C-reactive protein level (OR = 0.35 per SD; 95% CI: 0.13 to 0.92, P = 0.03) were associated with a reduced risk" 12/01/2000 - "The diagnosis of polymyalgia rheumatica (PMR) was made from the clinical symptoms, elevated C-reactive protein and erythrocyte sedimentation rate" 08/01/2000 - "Erythrocyte sedimentation rate and C-reactive protein in the evaluation of disease activity and severity in polymyalgia rheumatica: a prospective follow-up study." Order ALL the reference details at left...
5.	Prednisolone (Predate)FDA LinkGeneric 11/01/2006 - "In 1997, at the age of 68, a man was admitted with polymyalgia rheumatica, which was successfully treated with oral prednisolone" 01/01/2006 - "Polymyalgia rheumatica is treated with prednisolone" 09/01/2005 - "We report a patient with polymyalgia rheumatica (PMR) who showed a relapse soon after tapering of oral prednisolone" 12/04/2003 - "RESULTS: The average initial dose of prednisolone in polymyalgia rheumatica was 35 mg; 51 of 62 patients were given a starting dose exceeding 15 mg. INTERPRETATION: The recommended low initial dose of prednisolone has still been not implemented by the majority of general practitioners and rheumatologists." 03/01/2000 - "A diagnosis of polymyalgia rheumatica was made, and low-dose prednisolone therapy (20 mg/d) was started" Order ALL the reference details at left...
6.	infliximab (Remicade)FDA Link 05/01/2007 - "Adding infliximab to the treatment regimen for polymyalgia rheumatica." 04/01/2003 - "OBJECTIVE: To investigate whether infliximab has a steroid-sparing effect in the treatment of patients with polymyalgia rheumatica (PMR) who are resistant to corticosteroid (CS) therapy and have had CS-related side effects" 04/01/2003 - "Treatment of refractory polymyalgia rheumatica with infliximab: a pilot study." 10/01/2007 - "Infliximab is ineffective against giant cell arteritis and polymyalgia rheumatica]" 06/01/2003 - "In addition, Infliximab was also used with a good response in severe Polymyalgia rheumatica in 4 cases and in one case of a cryoglobulinemic vasculitis" Order ALL the reference details at left...
7.	Serum Amyloid A Protein (Serum Amyloid A)IBA 09/01/2005 - "Serum amyloid A as a potent therapeutic marker in a refractory patient with polymyalgia rheumatica." 06/01/2003 - "Serum amyloid A as a useful index of disease activity in polymyalgia rheumatica]" 08/01/2001 - "We encountered 3 cases of polymyalgia rheumatica (PMR), in which serum amyloid A (SAA) levels were correlated with clinical pictures after normalization of ESR and CRP levels" 08/01/2001 - "3 cases of polymyalgia rheumatica (PMR), in which serum amyloid A was a useful index of the disease activity]" 03/01/1991 - "Serum amyloid A concentrations in giant-cell arteritis and polymyalgia rheumatica: a useful test in the management of the disease." Order ALL the reference details at left...
8.	Etidronic Acid (HEDP)FDA LinkGeneric 12/01/1998 - "METHODS: A double blind, randomised placebo controlled study comparing cyclic etidronate and placebo during two years in 37 postmenopausal women receiving long term corticosteroid treatment, mainly for polymyalgia rheumatica (40% of the patients) and rheumatoid arthritis (30%)" 04/01/1999 - "We used a randomized placebo-controlled design to evaluate the efficacy of one-year cyclical etidronate therapy in preventing bone loss in 83 glucocorticoid-treated patients with rheumatoid arthritis, polymyalgia rheumatica, or giant cell arteritis" 04/01/1999 - "Etidronate prevents glucocorticoid-induced lumbar spine bone loss in patients with rheumatoid arthritis, polymyalgia rheumatica, or giant cell arteritis." 10/01/1994 - "Cohort study in a tertiary care university affiliated hospital in corticosteroid treated patients, with polymyalgia rheumatica, asthma, systemic lupus erythematosus, rheumatoid arthritis, or temporal arteritis, examining the effects of ICT etidronate" Order ALL the reference details at left...
9.	ApolipoproteinsIBA 03/01/1991 - "A prospective clinical study of 23 patients with giant-cell arteritis (GCA) and/or polymyalgia rheumatica (PMR) was undertaken in order to assess the behaviour of the non-specific markers of the disease activity, the erythrocyte sedimentation rate (ESR) and other acute phase markers, particularly the C-reactive protein (CPR) and serum amyloid A apolipoprotein (apo SAA) levels during induction of disease remission by prednisone therapy, and possible further recurrence of GCA and/or PMR" Order ALL the reference details at left...
10.	apolipoprotein SAAIBA 03/01/1991 - "A prospective clinical study of 23 patients with giant-cell arteritis (GCA) and/or polymyalgia rheumatica (PMR) was undertaken in order to assess the behaviour of the non-specific markers of the disease activity, the erythrocyte sedimentation rate (ESR) and other acute phase markers, particularly the C-reactive protein (CPR) and serum amyloid A apolipoprotein (apo SAA) levels during induction of disease remission by prednisone therapy, and possible further recurrence of GCA and/or PMR" Order ALL the reference details at left...

Therapies and Procedures

1.	Cardiopulmonary Resuscitation (CPR) 03/01/1991 - "A prospective clinical study of 23 patients with giant-cell arteritis (GCA) and/or polymyalgia rheumatica (PMR) was undertaken in order to assess the behaviour of the non-specific markers of the disease activity, the erythrocyte sedimentation rate (ESR) and other acute phase markers, particularly the C-reactive protein (CPR) and serum amyloid A apolipoprotein (apo SAA) levels during induction of disease remission by prednisone therapy, and possible further recurrence of GCA and/or PMR" Order ALL the reference details at left...
2.	Aftercare (After-Treatment) 03/01/1988 - "Twenty-three patients with polymyalgia rheumatica (PMR) followed in an academic rheumatology practice frequently reported symptoms commonly found in the recently described "chronic fatigue syndrome" or "chronic Epstein-Barr infection syndrome." These symptoms persisted for months after treatment had reduced the severity of the myalgias and lowered the sedimentation rate: periodically disabling fatigue (33%), recurrent pharyngitis (30%), sleep disorder (65%) and arthralgias (70%)" 02/21/1994 - "We assessed the diagnostic value of CD8+ levels in a larger group of patients with temporal arteritis and polymyalgia rheumatica before and after treatment with prednisolone and in relation to patients with other medical and rheumatic diseases" Order ALL the reference details at left...
3.	Kidney Transplantation 06/01/2002 - "Eleven patients had coexistent systemic disease: renal disease (six patients, including three post renal transplantation); valvular cardiac disease (two patients); one patient each had alcoholic cirrhosis, glioblastoma multiforme (on chemotherapy), and rheumatoid arthritis/polymyalgia rheumatica" 01/01/1996 - "Underlying diseases were leukaemia (n = 11), aplastic anaemia (n = 2), non-Hodgkin-lymphoma (n = 1), systemic lupus erythematosus (n = 1), kidney transplantation (n = 1), peritonitis after Billroth II anastomosis (n = 1), Polymyalgia rheumatica (n = 1), AIDS plus Burkitt lymphoma (n = 1), glioblastoma (n = 1), and subarachnoid haemorrhage (n = 1)" Order ALL the reference details at left...
4.	Transplantation (Transplant Recipients) 01/01/1986 - "Metacarpal bone measurements in renal transplant recipients, in corticosteroid-treated patients with polymyalgia rheumatica and in patients with primary hyperparathyroidism." 07/01/2001 - "Currently, high-dose oral corticosteroids are used to treat people with a variety of medical conditions, including: rheumatic diseases, such as rheumatoid arthritis, polymyalgia rheumatica, systemic lupus erythematosus and vasculitis; inflammatory lung diseases, like asthma; gastrointestinal diseases, such as inflammatory bowel disease and chronic liver disease; skin diseases, in particular pemphigus, and more recently those who have undergone transplantation" 01/01/1986 - "Quantitative radiological measurements on the second left metacarpal bone were carried out in 23 patients with primary hyperparathyroidism, 22 corticosteroid-treated patients with polymyalgia rheumatica and 40 renal transplant recipients treated with prednisone and azathioprine" Order ALL the reference details at left...
5.	Transplants (Transplant) 11/01/2008 - "Polymyalgia rheumatica in a renal transplant patient." Order ALL the reference details at left...

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