HOME PRODUCTS SERVICES COMPANY CONTACT FAQ

Polyethylene Glycols (Polyethylene Glycol)

Subscribe to New Research on Polyethylene Glycols

Polymers of ETHYLENE OXIDE and water and their ethers. They vary in consistency from liquid to solid, depending on the molecular weight, indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are lauromagrogols, nonoxynols, octoxynols and poloxamers.

Also Known As:

Polyethylene Glycol; Tritons; Polyethylene Oxide; Glycol, Polyethylene; Carbowax 600; Carbowax-400; Macrogol 300; PEG 1000; PEG 6000; PEG 8000; PEG-400; PEO-400; Peg 400; Polyethylene Glycol 2000; Polyethylene Glycol 300; Polyethylene Glycol 400; Polyethylene Glycol 4000; Polyethylene Glycol 6000; Polyethyleneoxide; Polyox FRA; Vigilon; 1000, PEG; 2000, Polyethylene Glycol; 300, Macrogol; 300, Polyethylene Glycol; 400, Polyethylene Glycol; 4000, Polyethylene Glycol; 600, Carbowax; 6000, PEG; 6000, Polyethylene Glycol; 8000, PEG; Carbowax 400; Carbowax400; FRA, Polyox; Glycol 2000, Polyethylene; Glycol 300, Polyethylene; Glycol 400, Polyethylene; Glycol 4000, Polyethylene; Glycol 6000, Polyethylene; Glycols, Polyethylene; Oxide, Polyethylene; PEO 400; Macrogols; Polyoxyethylenes

Networked: 1500 relevant articles (88 outcomes, 162 trials/studies) for this Drug, Comments

Relationship Network

Drug Context: Research Results

Experts

1.	Torchilin, Vladimir P: 9 articles (01/2010 - 10/2002)
2.	Shi, Riyi: 8 articles (05/2010 - 01/2002)
3.	Borgens, Richard B: 8 articles (01/2010 - 01/2002)
4.	Intaglietta, Marcos: 6 articles (04/2009 - 06/2003)
5.	Tsai, Amy G: 5 articles (10/2008 - 06/2003)
6.	Storm, Gert: 5 articles (04/2008 - 07/2003)
7.	Hauet, T: 5 articles (07/2006 - 12/2000)
8.	Cabrales, Pedro: 4 articles (10/2008 - 10/2004)
9.	McGowan, John: 4 articles (08/2008 - 07/2007)
10.	Luo, Jian: 4 articles (06/2007 - 10/2002)

Related Diseases

1.	Constipation 02/15/2010 - "In constipation, the conservative therapeutic option is administration of macrogol (polyethylene glycol), which leads to marked improvement." 11/01/1999 - "One long-term study observed remission of constipation-related symptoms in more than 70% of the polyethylene glycol electrolyte solution treated patients, and the efficacy of the treatment was maintained over a 6-month period, despite progressive reduction of daily dosage." 07/01/2006 - "Polyethylene glycol increases bowel frequency in chronic constipation, but its overall efficacy against IBS is unclear. " 02/01/2008 - "Daily polyethylene glycol over 6 months was effective for chronic constipation." 01/01/2008 - "Daily polyethylene glycol over 6 months was effective for chronic constipation." Order ALL the reference details at left...
2.	Neoplasms (Cancer) 11/08/2004 - "Efficacy of a safe and clinically utilized polyethylene glycol formulation (PEG-3350) to suppress intestinal tumors was investigated in the Apc(min) mouse-model of experimental carcinogenesis. " 06/01/1990 - "The efficacy of whole gut irrigation with polyethylene glycol electrolyte solution in elective colorectal surgery for cancer." 04/22/2009 - "In this study, we investigated the pharmacokinetics, biodistribution, and tumor uptake of sub-nanometer sized polymeric nanoparticles (<100 nm in diameter) coated with polyethylene glycol in tumor-bearing mice. " 07/01/2010 - "Tumor-specific gene transfer with receptor-mediated nanocomplexes modified by polyethylene glycol shielding and endosomally cleavable lipid and peptide linkers." 02/01/2010 - "Functional activity was measured in three groups: the DC single-culture group, the DC culture group with DC vaccine sensitized with tumor lysates, and the DC culture group prepared with tumor fusion vaccine made from irradiated tumor cells and monocyte-derived DCs by the polyethylene glycol method. " Order ALL the reference details at left...
3.	Infection 12/01/2007 - "GAG-dependent binding of HBV was improved by polyethylene glycol, a substance that specifically enhances HBV infection. " 12/01/1993 - "To study whether JHM resistance of these cell lines is due to a defective cellular factor necessary for JHM virus entry, or due to the presence of an inhibitor, hybrid cells were obtained by polyethylene glycol (PEG)-mediated fusion between two resistant cell lines, i.e., a Balb/c mouse-derived cell line, BC10 cells, which are resistant to JHM infection but express a viral receptor, and the simian cell line COS cells, which are resistant to JHM because of the absence of the viral receptor. " 03/01/2010 - "TRDeltagO particles released from fibroblasts failed to infect fibroblasts and epithelial and endothelial cells, but the chemical fusogen polyethylene glycol (PEG) could partially overcome defects in infection. " 08/01/2008 - "Conventional means such as Agrobacterium infection, biolistic particle bombardment, electroporation, or polyethylene glycol attachment are often characterized by high cost, labor extensiveness, and a significant perturbation to the growth of cells. " 10/01/2006 - "Thus, the 13C-urea-containing capsule with polyethylene glycol would be a more economical and sensitive preparation for diagnosis of Helicobacter pylori infection." Order ALL the reference details at left...
4.	Body Weight (Weight, Body) 12/01/1984 - "with polyethylene glycols (PEG) 20 min prior to head and neck X irradiation with 1650 rad showed improved survival, increased food and water consumption, and retention of body weight compared with irradiated controls. " 09/01/2007 - "Before the examination, patents received oral polyethylene glycol (PEG) (1,000 ml for adults; 10 ml/Kg of body weight for children). " 01/01/2004 - "They were fed (once a day) via a stomach tube with: i) 2 ml of polyethylene glycol (Peg); group Peg, ii) 2 ml of Peg + 2 ml of 25% v/v pure Alc in water; group Alc + Peg, iii) 2 ml of Gem solution in Peg (3.4 mg/100 g body weight); group Gem +Peg, iv) 2 ml of Gem solution in Peg 2 + 2 ml of Alc; group Gem +Alc +Peg. " 11/01/2000 - "Oral treatment with polyethylene glycol 200 (PEG) twice daily (n = 8), TBF twice daily (n = 9; 200 mg/kg of body weight/day), or FCZ once daily (n = 8; 80 mg/kg/day) began on day 5 and continued for 21 days. " 03/01/1995 - "Unanesthetized male Sprague-Dawley rats and beagle dogs were administered 1, 3, or 10 mg PCE/kg body weight in polyethylene glycol 400 as a single bolus, either by gavage or by intraarterial (ia) injection. " Order ALL the reference details at left...
5.	Spinal Cord Injuries (Spinal Cord Injury) 06/01/2009 - "Polyethylene glycol (PEG) has been reported to possess fusogenic properties that may confer neuroprotection after spinal cord injury (SCI), but there is uncertainty regarding the mechanisms of PEG in vivo and the robustness of its protective effects. " 06/01/2009 - "Systemic polyethylene glycol promotes neurological recovery and tissue sparing in rats after cervical spinal cord injury." 06/25/2007 - "Polyethylene glycol inhibits apoptotic cell death following traumatic spinal cord injury." 12/01/2004 - "In previous experiments using laboratory animals, we have exploited this capability using polyethylene glycol (PEG) to repair spinal axons after severe, standardized spinal cord injury (SCI) in guinea pigs. " 08/01/2004 - "Polyethylene glycol improves function and reduces oxidative stress in synaptosomal preparations following spinal cord injury." Order ALL the reference details at left...

Related Drugs and Biologics

1.	Liposomes (Liposome)
2.	Superoxide Dismutase
3.	Lactulose (Duphalac)
4.	Miralax
5.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
6.	Amphotericin B (Amphotericin)
7.	liposomal amphotericin B
8.	polyethylene glycol-superoxide dismutase
9.	Hemoglobins (Hemoglobin)
10.	Doxorubicin (Adriamycin)

Related Therapies and Procedures

1.	Injections
2.	Drug Therapy (Chemotherapy)
3.	Heterologous Transplantation (Xenotransplantation)
4.	Intravenous Infusions
5.	Enema (Enemas)

blog comments powered by Disqus

TREATMENT OPTIONS
for Constipation,
Ranking and Evidence

CureHunter Patient-Physician Summary Reports collect in one document all the medications ever reported in the US National Library of Medicine—1949 to the present—to be effective against your target disease. Analytic charts allow you and your physicians to see at a glance the treatment options—including new, promising, off-label and experimental.

Free Updates for 1 Year
All 369 Outcomes
Top 200 Key Drugs and Biologics
Top 50 Key Therapies and Procedures
Detailed History Charts
Full Research Evidence References
Sample PDF Report on Psoriasis >>

Price:

$8.50 USD & Delivery via PDF download
updates for 1 year

Research Interface PRO

Rapidly retrieve clinical outcome summaries for all evidence of drug efficacy against any disease in seconds. Click "Charts" to view graphs of relative efficacy of all drugs against any known disease. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time. Save hours of search and analysis time:

Two-clicks from Disease to Drug to Evidence: Drill down to full abstract
Enable Experts: Quickly identify key researchers and their publications
Enable FDA Link Generic: Two-clicks to FDA Products/Patents/Generics
Enable Export: All outcome statements and scores exportable to Excel/TSV for automated meta-analysis
Research Network: Explore drug and disease relationships visually
Enable Mobile Interface: Access from your cellphone, iPhone or PDA

Price:

$45.00 USD access via web interface
1 year subscription

Request Bulk Institution License Details >>