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Polycythemia Vera

A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and spleen). In time myelofibrosis occurs.
Also Known As:
Disease, Osler-Vaquez; Erythremias; Osler Vaquez Disease; Polycythemia Rubra Veras; Vera, Polycythemia Rubra; Veras, Polycythemia Rubra; Erythremia; Osler-Vaquez Disease; Polycythemia Rubra Vera
Networked: 1317 relevant articles (55 outcomes, 133 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Essential Thrombocythemia
2. Thrombocytosis (Thrombocythemia)
3. Pruritus (Itching)
4. Primary Myelofibrosis (Myelosclerosis)
5. Thrombosis (Thrombus)

Experts

1. Tefferi, Ayalew: 31 articles (04/2015 - 04/2002)
2. Verstovsek, Srdan: 27 articles (09/2015 - 10/2006)
3. Vannucchi, Alessandro M: 25 articles (05/2015 - 01/2007)
4. Barbui, Tiziano: 22 articles (10/2014 - 01/2003)
5. Finazzi, Guido: 18 articles (10/2014 - 01/2003)
6. Rambaldi, Alessandro: 16 articles (10/2014 - 08/2010)
7. Levine, Ross L: 16 articles (08/2013 - 04/2005)
8. Prchal, Josef T: 15 articles (10/2015 - 06/2004)
9. Guglielmelli, Paola: 15 articles (05/2015 - 11/2007)
10. Silver, Richard T: 14 articles (10/2015 - 08/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Polycythemia Vera:
1. Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
2. Hydroxyurea (Hydrea)FDA LinkGeneric
3. ErythropoietinFDA Link
4. Busulfan (Busulfex)FDA Link
5. Recombinant Interferon Type IIBA
6. InterferonsIBA
7. Interferon-alpha (Interferon Alfa)FDA Link
8. imatinib (Gleevec)FDA Link
9. Pipobroman (Vercyte)FDA Link
10. INCB018424IBA

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Bloodletting
3. Stem Cell Transplantation
4. Transplantation (Transplant Recipients)
5. Photochemotherapy (Photodynamic Therapy)