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Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)

Enzymes that catalyze the transfer of multiple ADP-RIBOSE groups from nicotinamide-adenine dinucleotide (NAD) onto protein targets, thus building up a linear or branched homopolymer of repeating ADP-ribose units i.e., POLY ADENOSINE DIPHOSPHATE RIBOSE.
Also Known As:
Poly ADP Ribose Polymerase; PARP Polymerase; Poly ADP Ribose Transferase; Poly ADP-Ribose Synthase; Poly(ADP-Ribose) Transferase; Poly(ADPR) Polymerase; Poly(ADPribose) Polymerase; Poly ADP Ribose Synthase; Polymerase, PARP; Synthase, Poly ADP-Ribose; ADP-Ribosyltransferase (Polymerizing); Poly(ADP-Ribose) Synthase; Poly(ADP-ribose) Polymerase; NAD+:poly(adenosine diphosphate D-ribose)-acceptor ADP-D-ribosyltransferase
Networked: 3538 relevant articles (162 outcomes, 327 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Szabó, Csaba: 68 articles (05/2017 - 01/2002)
2. Cuzzocrea, Salvatore: 27 articles (12/2016 - 01/2002)
3. Liaudet, Lucas: 23 articles (11/2020 - 01/2002)
4. Pacher, Pál: 23 articles (01/2015 - 01/2002)
5. Obrosova, Irina G: 22 articles (10/2011 - 08/2003)
6. Mazzon, Emanuela: 20 articles (09/2015 - 01/2002)
7. Kim, Sung-Hoon: 19 articles (01/2022 - 10/2004)
8. Zhang, Jie: 18 articles (12/2021 - 03/2002)
9. Szabo, Csaba: 16 articles (01/2022 - 04/2003)
10. O'Connor, Mark J: 15 articles (11/2021 - 08/2006)

Related Diseases

1. Neoplasms (Cancer)
2. Ovarian Neoplasms (Ovarian Cancer)
3. Breast Neoplasms (Breast Cancer)
4. Prostatic Neoplasms (Prostate Cancer)
5. Triple Negative Breast Neoplasms

Related Drugs and Biologics

1. Poly(ADP-ribose) Polymerase Inhibitors
2. olaparib
3. Enzymes
4. Poly Adenosine Diphosphate Ribose
5. Platinum
6. Proteins (Proteins, Gene)
7. Caspase 3 (Caspase-3)
8. veliparib
9. Caspase 9
10. rucaparib

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Immunotherapy
4. Radiotherapy
5. Precision Medicine