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Poliomyelitis (Polio)

An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)
Also Known As:
Polio; Infantile Paralysis; Paralysis, Infantile; Polios; Encephalitis, Polio; Epidemic Acute Poliomyelitis; Polio Encephalitis; Poliomyelitis, Acute; Acute Poliomyelitis; Acute Poliomyelitis, Epidemic; Nonpoliovirus Poliomyelitis; Poliomyelitides, Preparalytic; Poliomyelitis, Epidemic Acute; Preparalytic Poliomyelitis; Poliomyelitis, Nonpoliovirus; Poliomyelitis, Preparalytic
Networked: 4214 relevant articles (121 outcomes, 369 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Tetanus
2. Diphtheria
3. Whooping Cough (Pertussis)
4. Measles
5. Infection

Experts

1. Centers for Disease Control and Prevention (CDC): 39 articles (06/2015 - 03/2000)
2. Sutter, Roland W: 32 articles (12/2015 - 04/2003)
3. Pallansch, Mark A: 25 articles (11/2015 - 10/2004)
4. Thompson, Kimberly M: 22 articles (06/2015 - 12/2006)
5. Aylward, R Bruce: 17 articles (12/2015 - 01/2004)
6. Aaby, Peter: 17 articles (10/2014 - 01/2002)
7. Bakker, Wilfried A M: 15 articles (08/2015 - 04/2011)
8. Duintjer Tebbens, Radboud J: 15 articles (06/2015 - 12/2006)
9. Shimizu, Hiroyuki: 13 articles (05/2013 - 07/2005)
10. Smith, Philip J: 13 articles (07/2011 - 01/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Poliomyelitis:
1. VaccinesIBA
2. alpha-Fetoproteins (AFP)IBA
3. Oral Poliovirus Vaccine (Sabin Vaccine)IBA
4. Inactivated Poliovirus Vaccine (Salk Vaccine)FDA Link
5. AntibodiesIBA
6. Diphtheria-Tetanus-Pertussis Vaccine (DPT Vaccine)IBA
7. Poliovirus VaccinesIBA
8. Neutralizing AntibodiesIBA
9. infanrix hexaIBA
10. AntigensIBA

Therapies and Procedures

1. Injections
2. Transplantation (Transplant Recipients)
3. Arthroplasty
4. Activities of Daily Living (ADL)
5. Resistance Training