Lipid Pneumonia

Pneumonia due to aspiration or inhalation of various oily or fatty substances or otherwise accumulation of endogenous lipid substances in the PULMONARY ALVEOLI.

Also Known As:

Pneumonia, Lipid; Endogenous Lipid Pneumonias; Endogenous Lipoid Pneumonias; Exogenous Lipid Pneumonias; Exogenous Lipoid Pneumonias; Lipid Pneumonia, Endogenous; Lipid Pneumonia, Exogenous; Lipid Pneumonias; Lipoid Pneumonia, Endogenous; Lipoid Pneumonia, Exogenous; Lipoid Pneumonias; Pneumonia, Endogenous Lipid; Pneumonia, Endogenous Lipoid; Pneumonia, Exogenous Lipid; Pneumonia, Exogenous Lipoid; Pneumonia, Lipoid; Endogenous Lipid Pneumonia; Endogenous Lipoid Pneumonia; Exogenous Lipid Pneumonia; Exogenous Lipoid Pneumonia; Lipoid Pneumonia

Networked: 246 relevant articles (7 outcomes, 4 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Pulmonary Fibrosis (Fibrosing Alveolitis)
2.	Legionnaires' Disease (Legionnaire's Disease)
3.	Granuloma
4.	Fibrosis (Cirrhosis)
5.	Esophageal Achalasia (Megaesophagus)

Experts

1.	Marchiori, Edson: 4 articles (05/2011 - 11/2007)
2.	Zanetti, Gláucia: 4 articles (05/2011 - 11/2007)
3.	Lee, Jaehee: 3 articles (06/2021 - 04/2018)
4.	Padovani, Bernard: 2 articles (12/2019 - 06/2017)
5.	Gorospe, Luis: 2 articles (01/2018 - 01/2013)
6.	Hochhegger, Bruno: 2 articles (05/2011 - 01/2010)
7.	Mano, Claudia Mauro: 2 articles (05/2011 - 01/2010)
8.	Actor, Jeffrey K: 2 articles (01/2011 - 01/2006)
9.	Hunter, Robert L: 2 articles (01/2011 - 01/2006)
10.	Hadda, Vijay: 2 articles (12/2010 - 12/2009)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Lipid Pneumonia:

1.	SteroidsIBA 07/01/2012 - "We report a case of a two-and-a-half-year-old child with persistent lipoid pneumonia following accidental inhalation of machine oil, who was successfully treated with steroids." 07/01/2012 - "Severe lipoid pneumonia following aspiration of machine oil: successful treatment with steroids." 01/01/2001 - "Therefore it is concluded that the lipoid pneumonia was steroid dependent. " 03/01/1994 - "We describe a patient with idiopathic lipoid pneumonia who was successfully treated with oral steroids with improvement of chest radiographic abnormalities." 12/01/2018 - "Successful Steroid Therapy for Lipoid Pneumonia Developing After Allogeneic Hematopoietic Stem Cell Transplant: A Case Report."
2.	InsecticidesIBA 01/01/2012 - "We present a case of exogenous lipoid pneumonia due to aspiration of insecticide, for which the computed tomography findings of fat attenuation within the lesion were helpful in reaching a correct diagnosis." 01/01/2012 - "Exogenous lipoid pneumonia induced by aspiration of insecticide." 07/01/1999 - "In addition, we experimentally induced a similar form of lipoid pneumonia in rats by intratracheal instillation of the same insecticide." 07/01/1999 - "These findings together yielded a diagnosis of exogenous lipoid pneumonia induced by insecticide. " 07/01/1999 - "We report a case of exogenous lipoid pneumonia induced by insecticide. "
3.	Adrenal Cortex Hormones (Corticosteroids)IBA 01/01/2020 - "Rapid Resolution of Severe Vaping-induced Acute Lipoid Pneumonia after Corticosteroid Treatment." 01/01/2016 - "A treatment of choice for lipoid pneumonia has not been established, and systemic corticosteroid use remains controversial. " 01/01/2016 - "A severe case of acute exogenous lipoid pneumonia treated with systemic corticosteroid." 03/01/2014 - "Corticosteroids therapy was effective for patients with exogenous lipid pneumonia, which may inhibit the inflammatory response and possible pulmonary fibrosis." 10/18/2018 - "There were reports of lipoid pneumonia being successfully treated with corticosteroids, immunoglobulins, and whole-lung lavage. "
4.	Sesame Oil (Oil, Sesame)IBA 11/01/2022 - "Exogenous Lipoid Pneumonia Caused by Gargling With Sesame Oil: A Case Report." 10/30/2015 - "Exogenous lipoid pneumonia caused by repeated sesame oil pulling: a report of two cases." 10/30/2015 - "Steroid therapy and bronchoalveolar lavage resulted in improvement in Case 1, and no intensive therapy was required for Case 2. Sesame oil pulling has been rarely been reported to cause lipoid pneumonia."
5.	InflammasomesIBA 11/01/2023 - "MCC950 ameliorates sewing machine oil-induced acute exogenous lipoid pneumonia in rats through inhibition of the NF-[Formula: see text]B/NLRP3 inflammasome pathway." 11/01/2023 - "MCC950 Ameliorates Acute Exogenous Lipoid Pneumonia Induced by Sewing Machine Oil in Rats via the NF-κB/NLRP3 Inflammasome Pathway."
6.	N- (1,2,3,5,6,7- hexahydro- S- indacen- 4- ylcarbamoyl)- 4- (2- hydroxy- 2- propanyl)- 2- furansulfonamideIBA 11/01/2023 - "MCC950 ameliorates sewing machine oil-induced acute exogenous lipoid pneumonia in rats through inhibition of the NF-[Formula: see text]B/NLRP3 inflammasome pathway." 11/01/2023 - "MCC950 Ameliorates Acute Exogenous Lipoid Pneumonia Induced by Sewing Machine Oil in Rats via the NF-κB/NLRP3 Inflammasome Pathway."
7.	LipidsIBA 11/01/2023 - "Extrinsic lipoid pneumonia (ELP) results from the aspiration of lipid-containing substances. " 11/01/2023 - "Acute exogenous lipoid pneumonia (AELP) is a rare disorder caused by intake of lipid formulations and is often underdiagnosed. " 11/24/2022 - "Upon presentation to our institute, chest CT showed evidence of intraparenchymal fat; therefore, lipoid pneumonia and lipid storage disease were suspected. " 01/01/2022 - "Acute lipoid pneumonia is quite uncommon and is associated with oily or lipid contents within the alveoli. " 01/01/2022 - "The patient was diagnosed with exogenous lipoid pneumonia through an unusual route of lipid administration."
8.	Mineral Oil (Liquid Paraffin)FDA LinkGeneric 10/01/2022 - "Lipid pneumonia associated with mineral oil use presenting as fluorine-18-fluorodeoxy-D-glucose-avid lung mass." 10/01/2012 - "We present a rare case of acute exogenous lipoid pneumonia in a fire-eater who aspirated liquid paraffin during his flame-blowing show (fire-eater's lung). " 01/01/2010 - "Lipoid pneumonia in 53 patients after aspiration of mineral oil: comparison of high-resolution computed tomography findings in adults and children." 01/01/2010 - "Exogenous lipoid pneumonia is caused by inhalation or aspiration of animal fat or vegetable or mineral oil. " 01/01/2010 - "Exogenous lipoid pneumonia results from inhaling or aspirating animal, vegetable or mineral oil. "
9.	AntigensIBA 01/01/2011 - "Sections of characteristic lesions of caseating granulomas, lipid pneumonia, and cavitary stages of postprimary disease were selected for immunohistochemical studies of macrophages, lymphocytes, endothelial cells, and mycobacterial antigens. " 01/01/2006 - "New evidence indicates that secondary tuberculosis begins as a lipid pneumonia that accumulates mycobacterial antigens and host lipids in alveoli before developing conditions for activation of the toxicity and antigenicity of TDM. "
10.	beta Carotene (Betacarotene)FDA Link 01/01/2000 - "Histomorphological studies showed that the observed highly variable accumulation of beta-carotene in lung tissue was most probably due to an endogenously caused lipid pneumonia. "

Therapies and Procedures

1.	Therapeutics 09/01/2016 - "The treatment of lipoid pneumonia includes stopping the offending agents and providing supportive therapy. " 01/01/2015 - "In conclusion, a case of exogenous lipoid pneumonia was successfully treated with bronchoscopic segmental lavage therapy." 01/01/2015 - "Exogenous lipoid pneumonia successfully treated with bronchoscopic segmental lavage therapy." 01/01/2018 - "Two ladies with history of carcinoma of tongue presenting with un-resolving pneumonia were ultimately diagnosed to have lipoid pneumonia, and both were subsequently found to be associated with the practice of oil pulling which is a popular complementary therapy. " 12/01/2018 - "Successful Steroid Therapy for Lipoid Pneumonia Developing After Allogeneic Hematopoietic Stem Cell Transplant: A Case Report."
2.	Thoracotomy 12/01/1990 - "These procedures may help to avoid thoracotomy in elderly, often debilitated patients with lipoid pneumonia." 07/01/1998 - "The mass was resected during thoracotomy, and histopathology confirmed a diagnosis of endogenous lipid pneumonia. "
3.	Aftercare (After-Treatment) 03/01/2013 - "The patient's endogenous lipoid pneumonia resolved completely after treatment for Legionella pneumophila infection. "
4.	Myotomy 06/21/2023 - "His lipoid pneumonia improved after peroral endoscopic myotomy because of the reduction in aspiration risk."
5.	Laryngectomy 07/01/2015 - "Exogenous Lipoid Pneumonia in Laryngectomy Patients: Radiological Findings." 01/01/2007 - "[Lipoid pneumonia in patients after laryngectomy]." 01/01/2018 - "Lipoid pneumonia mimicking multifocal lung cancer in a patient with a remote laryngectomy and a recently diagnosed lung cancer: PET/CT findings." 06/01/1990 - "Lipoid pneumonia after laryngectomy mimicking pulmonary malignancy." 01/01/2016 - "Exogenous lipoid pneumonia in laryngectomy patients: Is ground glass opacity/crazy paving pattern an organizing pneumonia reaction that can predict poor outcome?"