|1.||Light, Richard W: 38 articles (05/2015 - 01/2002)|
|2.||Light, R W: 19 articles (01/2007 - 01/2000)|
|3.||Kalomenidis, Ioannis: 18 articles (07/2015 - 07/2003)|
|4.||Sahn, Steven A: 17 articles (03/2014 - 03/2002)|
|5.||Lee, Y C Gary: 16 articles (07/2015 - 07/2002)|
|6.||Porcel, José M: 12 articles (12/2015 - 04/2006)|
|7.||Wu, Guang-Ping: 9 articles (11/2015 - 07/2007)|
|8.||Creaney, Jenette: 9 articles (07/2015 - 09/2006)|
|9.||Gourgoulianis, Konstantinos I: 9 articles (07/2015 - 07/2005)|
|10.||Sone, Saburo: 9 articles (08/2012 - 02/2002)|
07/01/1995 - "Recent study results indicate that intrapleural instillation of iodized talc is an adequate and effective treatment for control of neoplastic or benign pleural effusion."
06/01/1995 - "The intrapleural insufflation of talc was effective in preventing recurrence of pleural effusion. "
05/01/1992 - "These observations indicate that intrapleural instillation of a slurry of iodized talc is a safe, adequate, and effective treatment for control of neoplastic or benign pleural effusions."
12/01/2011 - "Not more effective than talc in preventing recurrent pleural effusions, based on a review with meta-analysis of 7 trials in 256 patients. "
12/01/1994 - "The objective of this study is to present our experience with a low dose of aerosolized talc for controlling nonmalignant pleural effusions. "
|2.||Adrenal Cortex Hormones (Corticosteroids)IBA
01/01/2014 - "The patient was treated with high doses of corticosteroids, which rapidly reduced the size of her diffuse pulmonary nodules and dramatically improved her pleural effusion. "
09/03/1996 - "Corticosteroids led to rapid improvement with complete resolution of the pleural effusion."
09/01/1993 - "There was a good clinical and roentgenographic response and the pleural effusion responded well to corticosteroids. "
09/01/2006 - "The use of corticosteroids may be helpful in case of repeated, uncontaminated pleural effusions. "
05/01/1998 - "Further studies are needed to determine whether high-dose corticosteroids are also effective on the resolution of pleural effusions associated with other malignant disease."
01/01/1989 - "We suggest, therefore, that immunological monitoring may help to optimize treatment protocols for the treatment of peritoneal and perhaps pleural effusions with OK-432."
12/01/2012 - "Thoracic drainage with intrathoracic administration of OK-432 (Picibanil) had failed to control the pleural effusion. "
11/01/2007 - "Nineteen months following CRT, pleural effusion was noticed and thoracentesis was performed several times into both of the pleural cavities, and that was depending on the degree with OK-432 infusion. "
07/01/2004 - "We removed the pleural effusion and injected OK-432 into the chest cavity at 24 and 25 weeks of gestation. "
10/01/2001 - "OK-432 injection achieved rapid and effective control of pleural effusion with no adverse effects."
|4.||Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
09/01/2010 - "Intrapleural urokinase has been shown to be effective in the treatment of pleural effusions in children. "
11/01/2006 - "Our study shows that patients with loculated tuberculous pleural effusion treated with urokinase suffered less from residual pleural thickening, as measured after six months, than those treated by simple drainage. "
11/01/2006 - "A study of loculated tuberculous pleural effusions treated with intrapleural urokinase."
05/01/2005 - "The aim of the present study was to evaluate the utility of urokinase in the treatment of infectious pleural effusions in children. "
10/31/2004 - "The purpose of this study was to propose that intrapleural urokinase (UK) instillation could reduce pleural thickening in the treatment of loculated tuberculous pleural effusion. "
|5.||Anti-Bacterial Agents (Antibiotics)IBA
11/01/2014 - "Chest X-ray showed massive pleural effusion, thoracocentesis showed it as purulent exudate and she was empirically treated with antibiotics. "
09/01/2014 - "He was diagnosed with pleural effusion and started on antibiotics, as it was noted to be an exudative effusion. "
03/01/2014 - "Although the symptoms were alleviated by antibiotics, computed tomography (CT) showed an anterior mediastinal mass with bilateral pleural effusion. "
12/01/2008 - "Severe MP was characterized by rapid progression, pulmonary consolidation, moderate to severe pleural effusion, obviously increased inflammatory indexes, and poor therapeutic reaction to simple macrolide antibiotics. "
06/01/2005 - "Purulent pericardial and bilateral pleural effusion was diagnosed, and the patient was treated with antibiotics, repeated pleurocentesis and pericardial drainage with daily polihexanide lavage. "
|6.||Prednisolone (Predate)FDA LinkGeneric
11/01/1998 - "Treatment with an increased dose of prednisolone achieved a rapid remission of the pleural effusion. "
04/01/2011 - "Although his symptoms and pleural effusion improved with the administration of 30 mg/day prednisolone (PSL), these findings recurred after about 4 weeks. "
12/01/2012 - "After a month of treatment of prednisolone, the left pleural effusion had resolved, and after 2 months the serum CA-125 level was normalized."
09/01/2007 - "Prednisolone administered to reduce the pleural effusion."
12/01/2003 - "During the course of reducing the prednisolone dose by up to 5 mg per day, pleural effusion appeared in the right lung. "
|7.||Praziquantel (Biltricide)FDA Link
01/01/2008 - "Although Praziquantel, a highly effective agent for the treatment of lung flukes was repeatedly administered, the pleural effusion did not subside and the patient's condition gradually deteriorated until his death due to circulatory insufficiency. "
03/01/2003 - "The patients were treated with praziquantel for 3 days at a daily dosage of 75 mg/kg and their symptoms were relieved, but one case needed additional treatment with praziquantel for 3 days at a daily dosage of 50 mg/kg because of sustained pleural effusion and a persistently high antibody titer. "
12/01/2011 - "She was improved after 5 cycles of praziquantel treatment and 2 times of pleural effusion drainage. "
10/01/2009 - "Treatment with praziquantel at 75 mg/kg for 3 days, for 2 repeated courses, ameliorated the pleural effusion and decreased the antibody titers. "
07/01/2005 - "The patient received drainage of pleural effusion again, and was treated with praziquantel for 3 days at a daily dosage of 75 mg/kg in a series of three treatments at three week interval. "
|8.||Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/01/2010 - "Efficacy of anti-VEGF therapy for refractory pleural effusions needs to be defined through further studies."
03/01/2009 - "In the present study, whether or not vascular endothelial growth factor (VEGF) contributes to the induction and/or maintenance of Tregs was examined, because of experience with a patient in whom a positive correlation between VEGF concentration and the percentage of Tregs (% Tregs) among the total CD4(+) T-cells in the pleural effusion was found during dendritic cell activated lymphocyte therapy. "
01/01/2008 - "The purpose of the study was to evaluate predictive value of vascular endothelial growth factor (VEGF) in the differential diagnosis of pleural effusion. "
07/01/2005 - "In conclusion, although VEGF levels in pleural effusions of different origins vary, they were only able to discriminate exudates from transudates significantly in this study. "
04/01/2005 - "This study aimed to determine the diagnostic relevance of vascular endothelial growth factor (VEGF) in the pleural fluid and serum of patients with pleural effusions of different aetiology. "
|9.||Cisplatin (Platino)FDA LinkGeneric
04/30/2015 - "Cisplatin concentrations in the collected pleural effusion and blood were measured and compared by repeated measurement ANOVA. "
09/15/2002 - "Despite the poor survival of patients with advanced (stage IIIB with pleural effusion or stage IV) non-small-cell lung cancer, the introduction of new chemotherapeutic agents has improved survival and quality of life with reduced toxicity compared with older cisplatin-based therapies. "
04/01/2006 - "However, this cycle active agent often is administered with cisplatin to patients who may have pleural effusions and ascites. "
06/01/1993 - "Intraoperative intrapleural hypotonic cisplatin was instilled in seven patients with pleural carcinomatosis without side effects and with control of pleural dissemination and pleural effusion for 6 to 29 months."
02/01/1995 - "We investigated gene-specific damage in adenocarcinoma cells, obtained from pleural effusions of 9 primary lung cancer patients, induced by incubation with cisplatin for 3 h in vitro. "
|10.||Cyclophosphamide (Cytoxan)FDA LinkGeneric
07/01/1996 - "Massive pleural effusion attributed to high-dose cyclophosphamide during conditioning for BMT."
01/01/1978 - "Treatment with cyclophosphamide was followed by clinical improvement and the disappearance of the pleural effusion."
12/01/1998 - "Hypoalbuminemia and low serum levels of complements improved remarkably and the pleural effusion and ascites disappeared after cyclophosphamide pulse therapy four times monthly. "
07/01/1996 - "A 37-year-old male developed massive pleural effusion leading to respiratory failure and electromechanical dissociation within 24 h after the second dose of 4200 mg cyclophosphamide (CY) during conditioning for allogeneic bone marrow transplantation for chronic myelogenous leukemia. "
01/01/1992 - "He responded well to corticosteroids and cyclophosphamide with resolution of the pleural effusions and improvement of the clinical picture. "
05/01/2015 - "The nature of recurrent pleural effusions mandates that any definitive and effective treatment of this condition should ideally provide direct visualization of the effusion, complete initial drainage, a low risk outpatient procedure, a high patient satisfaction rate, a high rate of pleurodesis and a high diagnostic yield for tissue diagnosis. "
11/01/2006 - "Overall, this review supports the safety and efficacy of iodopovidone as an agent for chemical pleurodesis in cases of recurrent pleural effusions and pneumothoraces regardless of their etiology."
04/01/2002 - "Accordingly, pleurodesis with minocyclin was undertaken, which was fortunately effective for controlling the pleural effusion."
03/01/2012 - "Iodopovidone may be considered a safe and effective agent for chemical pleurodesis in patients with pleural effusions and recurrent pneumothoraces."
03/01/2007 - "To assess whether intractable pleural effusions in pediatric oncology patients at end of life could be sufficiently relieved by pleurodesis. "
08/01/1992 - "Early in utero catheter drainage may provide the best treatment for the pleural effusions associated with thoracic sequestrations, although this therapy remains under investigation."
12/01/2012 - "To describe the safety and efficacy of thoracoamniotic shunting for fetal pleural effusion using a double-basket catheter with a very small diameter (1.47 mm). "
09/01/2015 - "Tunneled pleural catheters have been established to be safe and effective in the management of recurrent symptomatic pleural effusions. "
01/01/2015 - "In the central venous catheter group, catheterization in the thoracic cavity was performed once in all cases, without fall-off; the mean total volume of pumped effusion was 3932±4430 ml; the time to disappearance of pleural effusion and pneumatosis was 10±2 d; 40 (83.33%) of the 48 cases were cured. "
02/01/1999 - "Subcutaneous access ports with fenestrated catheters for improved management of recurrent pleural effusions."
|3.||Drug Therapy (Chemotherapy)
07/01/2014 - "Chemotherapy is the mainstay of treatment for myelomatous pleural effusion. "
10/01/2007 - "To evaluate the clinical efficacy of Xiaoshui Powder as auxiliary with chemotherapy for treatment of tuberculous remnant pleural effusion. "
02/01/1996 - "The patient achieved remission with chemotherapy, but she later relapsed, with right pleural effusion, and died. "
02/01/2006 - "In this patient group, presenting with stable symptoms after control of pleural effusion, the early use of chemotherapy provided an extended period of symptom control, and in this small trial a trend to survival advantage."
07/01/2005 - "Important national trials are ongoing: in the UK the addressed questions were the role of radical surgery (MARS Trial), the role of chemotherapy (MS-01 trial) and the role of VATS on active treatment of pleural effusion. "
|4.||Chest Tubes (Chest Tube)
10/01/1988 - "The examination contributed valuable information that aided in planning and evaluating therapy: (1) it assessed mediastinal and pleural cavity involvement prior to surgery or drainage; (2) it evaluated the efficacy of drainage; (3) it gave excellent information about the position of chest tubes; and (4) it demonstrated unsuspected pneumothoraces, pleural effusion, pulmonary infiltrates, and lung perforation by a chest tube. "
11/01/2009 - "Out-patient chest tube drainage is effective for the management of both malignant and suppurative pleural effusion. "
04/01/2014 - "Postoperatively, he required additional right transthoracic drainage by chest tube for pleural effusion on hospital day 5. Then his clinical and radiological findings gradually improved, and he was discharged from hospital day 37. "
04/01/1998 - "This study suggested that the curved chest tube would be safe and useful in completing drainage of pleural effusion."
01/01/2016 - "We inserted a chest tube through the 6th intercostal space in the anterior axillary line in order to prevent postoperative massive pleural effusion. "
08/01/2015 - "Virus in sputum disappeared after treatment, but pleural effusion was not completely absorbed. "
06/01/2012 - "Lesions form: little patchy shadow in 8 cases (8/8), fibrous band shadow in 4 cases (4/8), ground glass shadow in 3 cases (3/8), peripheral fuzzy interlobular nodule in 4 cases (4/8); 5 cases complicated with pleural effusion; After treatment 6 ∼ 10 days, the pulmonary shadows were absorbed obviously; Fibrous band shadow was residual in a case after a follow-up of 2 months. "
12/01/2011 - "In the SIATS group, operative time was 140 - 220 min, the blood loss was 160 - 1500 ml the correction of Cobb's angle was 15° - 25°, 1 case had pleural effusion, 1 had lateral femoral cutaneous nerve damage, the complications disappeared after treatment. "
09/01/2009 - "The levels of TGF-beta(1) in the pleural effusion showed no significant difference before and after treatment (P > 0.05). "
03/01/2006 - "Pleural effusions developed after treatment in six patients (25%), which proved to be malignant in one patient. "