|1.||Markman, Maurie: 52 articles (03/2014 - 02/2002)|
|2.||Sehouli, Jalid: 44 articles (05/2015 - 06/2003)|
|3.||Vergote, Ignace: 41 articles (12/2015 - 01/2003)|
|4.||Scambia, Giovanni: 32 articles (07/2015 - 01/2003)|
|5.||Vergote, I: 26 articles (01/2014 - 01/2000)|
|6.||Coleman, Robert L: 25 articles (04/2015 - 01/2002)|
|7.||Sood, Anil K: 24 articles (10/2015 - 08/2003)|
|8.||Gershenson, David M: 23 articles (08/2015 - 05/2002)|
|9.||Lippard, Stephen J: 23 articles (03/2015 - 12/2002)|
|10.||Zhang, Wei: 22 articles (09/2015 - 08/2004)|
07/01/1998 - "These tumors are highly responsive to therapy with platinum-containing regimens, and 80% of cases so treated can be considered cured. "
09/01/2011 - "Cis-platin and other platinum complexes are important chemotherapeutic agents useful in the treatment of several cancers. "
05/01/2008 - "However, after 2 to 3 months of complete remission following platinum treatment, tumors relapse and become refractory to successive rounds of treatment. "
01/01/2014 - "Although this regimen is initially effective in a high percentage of cases, unfortunately within few months of initial treatment, tumor relapse occurs because of platinum-resistance. "
01/01/2014 - "Platinum-based chemotherapeutics are the mainstay of treatment of a range of tumors achieving high response rates but limited in the course of disease by appearance of drug resistance. "
|2.||Ovarian Neoplasms (Ovarian Cancer)
01/01/2006 - "By contrast, most studies indicate that women developing a BRCA1/2-related ovarian cancer have an improved survival compared with non-carriers, particularly if they receive platinum-based therapy. "
01/01/2014 - "Following elderly ovarian cancer patients over a lifetime using real-world longitudinal data and adjusting for quality of life, we found that treatment with platinum-based regimen was the most cost-effective treatment alternative."
01/01/2013 - "In women with platinum-sensitive recurrent ovarian cancer, ability to achieve surgery with complete cytoreduction (no visible residual disease) is associated with significant improvement in overall survival. "
01/01/1993 - "Platinum-containing regimens are very effective in the primary treatment of ovarian cancer. "
05/01/2014 - "The standard platinum-based treatment of previously untreated advanced ovarian cancer continues to evolve because despite high response rates to such first-line treatment, a majority of patients will experience relapse. "
|3.||Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
03/01/2010 - "Standard first-line therapy for non-small-cell lung cancer (NSCLC) with platinum-based agents, given in combination with cytotoxic compounds, has reached a relative plateau in its therapeutic efficacy. "
08/01/2007 - "Third-generation platinum-based combinations are established as first-line treatment for advanced non-small cell lung cancer (NSCLC). "
10/01/2007 - "The aim of this study was to determine the impact of patient selection based on age, comorbidity and performance status on the efficacy of platinum-free combination therapy on non-small-cell lung cancer after 65 years of age. "
11/01/2013 - "Platinum doublets as first-line treatment for elderly patients with advanced non-small cell lung cancer."
02/01/2012 - "Platinum-based regimens represent the standard first-line treatment for non-small-cell lung cancer (nsclc). "
08/01/2011 - "Intratumoral lymphocyte density in serous ovarian carcinoma is superior to ERCC1 expression for predicting response to platinum-based therapy."
04/01/2015 - "This review summarizes the current status of first-line treatment of metastatic urothelial carcinoma in platinum-eligible patients as well as prognostic and predictive models in this disease. "
01/01/2015 - "Platinum-based combination therapy is the standard first-line treatment for women with advanced serous epithelial ovarian carcinoma (EOC). "
04/01/2003 - "To estimate the antitumor efficacy of dolastatin-10 in patients with measurable recurrences of platinum-sensitive ovarian carcinoma and to determine the nature and degree of toxicity of dolastatin-10 in these patients. "
01/01/2015 - "However, previous studies have revealed that some histological subtypes, such as clear cell carcinoma, are resistant to medical treatment, including that with platinum drugs. "
|5.||Lung Neoplasms (Lung Cancer)
05/01/2009 - ": Although platinum-based combinations are considered the best option of care for patients with advanced nonsmall cell lung cancer (NSCLC), single-agent therapy is the preferred treatment for older patients. "
02/01/2002 - "These agents may be particularly useful in the treatment of lung cancer, both as adjunctive therapy in early-stage or locally advanced disease, as well as in combination strategies with platinum-based therapy in metastatic disease. "
09/22/2015 - "Our previous study identified that it was correlated with platinum response in lung cancer. "
03/01/2014 - "Confocal fluorescence microscopy was used to study a platinum-based anticancer agent in intact NCI-H460 lung cancer cells. "
01/01/2013 - "The large LUX-Lung 3 phase III trial recently reported afatinib to be clearly superior over the most effective platinum doublet in patients with EGFR mutation-positive lung cancer. "
|1.||Drug Therapy (Chemotherapy)
|2.||Combination Drug Therapy (Combination Chemotherapy)
|5.||Heterologous Transplantation (Xenotransplantation)