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Platelet Factor 4

A CXC chemokine that is found in the alpha granules of PLATELETS. The protein has a molecular size of 7800 kDa and can occur as a monomer, a dimer or a tetramer depending upon its concentration in solution. Platelet factor 4 has a high affinity for HEPARIN and is often found complexed with GLYCOPROTEINS such as PROTEIN C.
Also Known As:
Heparin Neutralizing Protein; PF4 (Platelet Factor 4); gamma-Thromboglobulin; CXCL4, Chemokine; Chemokine, CXCL4; gamma Thromboglobulin; Antiheparin Factor; CXCL4 Chemokine; Chemokine CXCL4; Blood platelet factor 4
Networked: 694 relevant articles (10 outcomes, 60 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Greinacher, Andreas: 21 articles (11/2015 - 01/2005)
2. Warkentin, Theodore E: 16 articles (07/2015 - 01/2005)
3. Poncz, Mortimer: 13 articles (01/2015 - 02/2002)
4. Cines, Douglas B: 12 articles (01/2015 - 02/2002)
5. Gruel, Yves: 11 articles (04/2015 - 02/2003)
6. Walenga, Jeanine M: 11 articles (03/2015 - 01/2002)
7. Kowalska, M Anna: 10 articles (12/2012 - 11/2004)
8. Pouplard, Claire: 9 articles (04/2015 - 11/2004)
9. Rauova, Lubica: 9 articles (01/2015 - 11/2004)
10. Sachais, Bruce S: 9 articles (11/2013 - 12/2003)

Related Diseases

1. Thrombocytopenia (Thrombopenia)
2. Myocardial Ischemia (Ischemic Heart Diseases)
3. Diabetes Mellitus
4. Atopic Dermatitis (Atopic Eczema)
5. Acute Coronary Syndrome

Related Drugs and Biologics

1. beta-Thromboglobulin
2. Heparin (Liquaemin)
3. Antibodies
4. Fibrinopeptide A
5. Thrombin
6. Antithrombin III
7. Blood Proteins (Serum Proteins)
8. Hirudins
9. Collagen Type II (Type II Collagen)
10. Factor XIII (Coagulation Factor XIII)

Related Therapies and Procedures

1. Lasers (Laser)
2. Renal Dialysis (Hemodialysis)
3. Cardiopulmonary Bypass (Heart-Lung Bypass)
4. Intensive Care (Surgical Intensive Care)
5. Aftercare (After-Treatment)