Picloram

01/01/2011 - "Using mouse neuroblastoma (N2a) cells and primary neurons from C57BL/6 mice, we investigated the toxicity of these herbicides, and protective effects of SS1 peptide against picloram and triclopyr toxicity. "

02/01/1981 - "Male and female mice exposed to picloram developed neoplasms of the spleen in the National Cancer Institute mouse study. "
02/01/1981 - "Neoplasms at all sites, including malignant neoplasms, were increased in male and female rats given both low and high doses of picloram in the National Cancer Institute rat study. "
02/01/1981 - "Neoplasms were also increased in the liver of male and female rats and in the reproductive organs of female rats given picloram. "
01/01/1978 - "In female rats, however, the incidence of neoplastic nodules of the liver, benign tumors, was associated with treatment with picloram. "
01/01/1978 - "No tumors were found in male or female mice or male rats at incidences that could be significantly associated with treatment, and it is concluded that picloram was not carcinogenic for B6C3F1 mice or male Osborne-Mendel rats. "

07/01/2002 - "In general, within the limitations of the power of the study, the results did not show any evidence that exposure to a herbicide formulation containing 2,4-D and picloram is likely to cause male-mediated birth defects or other adverse reproductive outcomes."

01/01/1978 - "Body weights of the mice were unaffected by the picloram. "
05/01/2002 - "The high dose corresponded to 150 mg/kg body weight 2,4-D and 37.5 mg/kg picloram acid equivalents. "
06/01/1991 - "Channel catfish (Ictalurus punctatus) exposed to a mixture of picloram and 2,4-dichlorophenoxyacetic acid (2,4-D) for 10 days displayed increased activities of hepatic ethoxyresorufin O-deethylase (EROD), decreased serum chloride concentrations and decreased liver/body weight ratios. "
08/01/1985 - "Artificially inseminated rabbits were given 0, 40, 200 or 400 mg picloram acid equivalent/kg body weight/day in the form of picloram potassium salt in aqueous solution on days 6 to 18 of gestation. "

10/01/2017 - "Protective role of humic acids against picloram-induced genomic instability and DNA methylation in Phaseolus vulgaris."