Phosvitin

An egg yolk phosphoglycoprotein which contains about 90% of the yolk protein phosphorus. It is synthesized in the liver of the hen and transferred to the developing oocyte, where it is bound to lipoproteins within the yolk granules.

Also Known As:

Networked: 13 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Ahn, Dong Uk: 2 articles (08/2014 - 12/2012)
2.	Andersen, Øivind: 1 article (11/2017)
3.	Kirste, Katrine Hånes: 1 article (11/2017)
4.	Mommens, Maren: 1 article (11/2017)
5.	Naeve, Ingun: 1 article (11/2017)
6.	Timmerhaus, Gerrit: 1 article (11/2017)
7.	Tveiten, Helge: 1 article (11/2017)
8.	Xu, Chunxia: 1 article (11/2017)
9.	Lee, Jae Hoon: 1 article (08/2014)
10.	Lee, Minhee: 1 article (08/2014)

Related Diseases

1.	Melanoma (Melanoma, Malignant) 12/01/2012 - "The aim of this study was to investigate the effect of phosvitin on the inhibition of melanogenesis in melanoma cells. " 12/01/2012 - "In addition, phosvitin reduced the cellular cAMP concentration in B16F10 melanoma cells. " 12/01/2012 - "Addition of phosvitin at a concentration of 50μg/ml, to B16F10 melanoma cells inhibited tyrosinase activity by approximately 42% and melanin synthesis by 17% compared to those in a control without phosvitin. " 12/01/2012 - "Phosvitin inhibited the expression of tyrosinase, tyrosinase-related protein 1 (TRP-1), TRP-2, and microphthalmia-associated transcription factor (MITF) in B16F10 melanoma cells. "
2.	Iron Deficiencies 01/01/1986 - "Potential role of in vitro iron bioavailability studies in combatting iron deficiency: a study of the effects of phosvitin on iron mobilization from pinto beans."
3.	Neoplasms (Cancer) 08/01/2014 - "Among the cancer cell lines tested, MCF-7 and SK-MES-1 were the least sensitive and HeLa, AGS, and HepG2 were the most sensitive to phosvitin. " 08/01/2014 - "The growth of all cancer cell lines was inhibited in a dose-dependent manner by phosvitin. " 08/01/2014 - "Using the 3-[4,5-dimethythiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) assay, the cytotoxicity of phosvitin was evaluated in human cancer cell lines of various tissue origins, including the cervix (HeLa), breast (MCF-7), stomach (AGS), lung (A549 and SK-MES-1), liver (HepG2), and larynx (Hep-2). " 11/01/1984 - "histone, phosvitin, casein phosphokinases) are distinctly more active in tumor cells. " 06/01/1982 - "Similar hydrogen ion dependence (pH 6-7) and approximate association constants (Ka approximately 0.1 microM) were observed for the enzymes existing in both normal and tumor tissues, while the cAMP-dependent tumor protein kinase was found to phosphorylate phosvitin and casein to a greater degree. "
4.	Tetraploidy 11/01/2017 - "Here, we clarify the evolutionary history of vertebrate Vtgs, including the teleost VtgC, which lacks phosvitin, and investigate the repertoire of Vtgs and VtgRs in the tetraploid Atlantic salmon (Salmo salar). " 11/01/2017 - "Resolving the complexity of vitellogenins and their receptors in the tetraploid Atlantic salmon (Salmo salar): Ancient origin of the phosvitin-less VtgC in chondrichthyean fishes."
5.	Non-Hodgkin Lymphoma (Lymphosarcoma) 09/01/1976 - "Both the cAMP-dependent protein phosphotransferase activity and the phosvitin phosphotransferase activity are 2-to 4-fold elevated in the lymphosarcoma cells in comparison to thymocytes. "

Related Drugs and Biologics

1.	Iron
2.	Protein Kinases (Protein Kinase)
3.	Histones (Histone)
4.	Caseins (Casein)
5.	Proteins (Proteins, Gene)
6.	Phosphotransferases (Kinase)
7.	Microphthalmia-Associated Transcription Factor
8.	Vitellogenins (Vitellogenin)
9.	Monophenol Monooxygenase (Tyrosinase)
10.	Protons (Proton)