Leptophos

02/01/1989 - "And one out of 9 hens (11.1%) given RIVInj of 3 mg/kg leptophos for 5 days was affected with ataxia. "
02/01/1985 - "Hens treated with EPN developed irreversible ataxia after repeated exposure to as little as 1.3 mg/kg dermally or 5 mg/kg/day orally, while leptophos was neurotoxic at doses of 6-7 mg/kg/day dermally and 10 mg/kg/day orally. "
01/01/1977 - "Additional particular properties of both Leptophos and EPN were found in their ability to cause delayed neurotoxic ataxia in chickens and sheep fed once on sublethal doses of these compounds. "
01/01/1977 - "On the other hand, Leptophos and EPN when administered orally at sublethal or lethal levels clearly produced a delayed neurotoxic ataxia in treated mice. "
02/01/1989 - "The repeated intravenous injections (RIVInj) of 5 mg/kg/day leptophos [O-(4-bromo-2, 5-dichlorophenyl) O-methyl phenylphosphonothioate] for 3 consecutive days caused delayed ataxia in 4 out of 9 hens (44.4%). "

07/01/1983 - "The results indicated that leptophos induced severe ataxia and paralysis in sheep following about 4 months of treatment. "
01/01/1978 - "Thus leptophos caused ataxia, with subsequent paralysis, loss of appetite, and slow-down in the growth rate of the treated birds. "
01/01/1984 - "All the TOCP- and leptophos-treated ducks developed clinical signs of delayed neuropathy, as manifested by ataxia and paralysis. "

12/01/1980 - "[Effect of experimental thinness and obesity on the delayed neurotoxicity of the organophosphorus pesticide "Phosvel" (author's transl)]."

12/01/1982 - "Leptophos is a potent acetylcholinesterase inhibitor which causes delayed central-peripheral neuropathy. "

12/01/1980 - "[Effect of experimental thinness and obesity on the delayed neurotoxicity of the organophosphorus pesticide "Phosvel" (author's transl)]."