Phosphotungstic Acid (Acid, Phosphotungstic)

Tungsten hydroxide oxide phosphate. A white or slightly yellowish-green, slightly efflorescent crystal or crystalline powder. It is used as a reagent for alkaloids and many other nitrogen bases, for phenols, albumin, peptone, amino acids, uric acid, urea, blood, and carbohydrates. (From Merck Index, 11th ed)

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Networked: 99 relevant articles (1 outcomes, 4 trials/studies)

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Bio-Agent Context: Research Results

Experts

1.	Hou, Mai: 2 articles (01/2017 - 05/2009)
2.	Zhang, Hao: 2 articles (01/2017 - 05/2009)
3.	Zheng, Zhe: 2 articles (01/2017 - 05/2009)
4.	Aluko, Oritoke M: 1 article (09/2022)
5.	Ebokaiwe, Azubuike P: 1 article (09/2022)
6.	Ijomone, Omamuyovwi M: 1 article (09/2022)
7.	Okoh, Comfort O A: 1 article (09/2022)
8.	Liu, Sile: 1 article (01/2022)
9.	Shang, Dongmei: 1 article (01/2022)
10.	Wang, Hailong: 1 article (01/2022)

Related Diseases

1.	Rhabdomyosarcoma 08/01/1983 - "The tumor showed typical features of rhabdomyosarcoma; phosphotungstic acid hematoxylin (PTAH)-positive myofibrils and cross-striations were observed in the cytoplasm of highly plemorphic tumor cells." 07/01/1996 - "Juvenile rhabdomyosarcomas were diagnosed in two young dogs based on the results of histopathology, phosphotungstic acid-hematoxylin stain, immunohistochemistry, and the age of the dogs. " 07/01/1982 - "Phosphotungstic acid hematoxylin (PTAH) and oil red O staining of air-dried smears were helpful in differentiating MFH from pleomorphic variants of liposarcoma and rhabdomyosarcoma."
2.	Liposarcoma 07/01/1982 - "Phosphotungstic acid hematoxylin (PTAH) and oil red O staining of air-dried smears were helpful in differentiating MFH from pleomorphic variants of liposarcoma and rhabdomyosarcoma."
3.	Neoplasms (Cancer) 09/01/2009 - "Some tumor cells were stained blue with phosphotungstic acid hematoxylin. " 01/01/2006 - "Phosphotungstic acid-hematoxylin staining revealed cytoplasmic striations in scattered tumor cells. " 07/01/1999 - "The tissue fragment confirmed the presence of an epithelial tumor composed of trabecular sheets of clear cells, with numerous cytoplasmic granules which stained with phosphotungstic acid hematoxylin (PTAH). " 08/01/1983 - "The tumor showed typical features of rhabdomyosarcoma; phosphotungstic acid hematoxylin (PTAH)-positive myofibrils and cross-striations were observed in the cytoplasm of highly plemorphic tumor cells." 08/01/1980 - "Most of the tumor cells had processes that stained blue with phosphotungstic acid hematoxylin, suggesting the appearance of a glioma. "
4.	Scrapie 07/01/2005 - "Phosphotungstic acid precipitation is therefore a useful adjunct to WB analysis of scrapie and CWD and tissues." 02/01/2023 - "Proteinase K digestion followed by ultracentrifugation-based isolation or phosphotungstic acid-based isolation were employed to minimize the contribution of those background molecules, making this approach suitable for quantitating the amount of the K171 polymorphism in heterozygous scrapie infected sheep." 07/01/2005 - "Evaluation of Western blotting methods using samples with or without sodium phosphotungstic acid precipitation for diagnosis of scrapie and chronic wasting disease." 01/15/2007 - "PrPSc was precipitated from scrapie-infected brain stem and cerebellum tissue following sarkosyl extraction, with or without the use of sodium phosphotungstic acid, and native and denatured PrPSc detected by CDI. " 07/01/2005 - "The purpose of this study was to enhance the sensitivity of the Western blot (WB) test for use as an alternative and confirmatory method for the diagnosis of scrapie and chronic wasting disease (CWD) in Canada by comparing 2 sample preparation procedures: an abnormal prion protein (PrPSc) concentration procedure using sodium phosphotungstic acid (PTA) precipitation and a procedure using crude sample without precipitation. "
5.	Glioma (Gliomas) 01/01/1990 - "The synaptoarchitectonics of different structural formations (cortex, hippocampus, amygdaloid complex) were assayed in 3 patients with epilepsia and 2 patients with associated temporal lobe glioma and epileptic syndrome using a selective technique of staining synapses with phosphotungstic acid and their morphometric study. " 08/01/1980 - "Most of the tumor cells had processes that stained blue with phosphotungstic acid hematoxylin, suggesting the appearance of a glioma. "

Related Drugs and Biologics

1.	Hematoxylin (Haematoxylon)
2.	oil red O
3.	Coloring Agents (Dyes)
4.	Sodium
5.	Ethanol (Ethyl Alcohol)
6.	Prion Proteins
7.	Eosine Yellowish-(YS) (Eosin)
8.	Proteins (Proteins, Gene)
9.	Glutaral (Glutaraldehyde)
10.	Fibrin