|1.||Frostegård, Johan: 19 articles (02/2015 - 09/2006)|
|2.||Bhujwalla, Zaver M: 14 articles (06/2015 - 04/2003)|
|3.||Glunde, Kristine: 14 articles (06/2015 - 10/2003)|
|4.||de Faire, Ulf: 12 articles (01/2014 - 09/2006)|
|5.||Leach, Martin O: 8 articles (01/2014 - 09/2003)|
|6.||Workman, Paul: 7 articles (01/2014 - 11/2003)|
|7.||Harnett, William: 6 articles (11/2015 - 08/2003)|
|8.||Gribbestad, Ingrid S: 6 articles (06/2014 - 07/2010)|
|9.||Su, Jun: 6 articles (01/2014 - 09/2006)|
|10.||Griffiths, John R: 6 articles (02/2012 - 02/2002)|
10/01/2015 - "Using mass spectrometry and murine upper airway infection models, we demonstrated that phosphorylcholine (ChoP) moieties that are shared by PAF and the bacterial cell wall allow S. "
02/01/2008 - "Novel phosphorylcholine-containing protein of Pseudomonas aeruginosa chronic infection isolates interacts with airway epithelial cells."
06/15/2003 - "Abs specific for phosphorylcholine (PC) are known to contribute to the immune defense against a variety of microbial infections. "
11/01/1999 - "Phosphorylcholine is an important hapten that modulates the immune responses in Trichinella infections. "
09/01/1999 - "Monoclonal phosphorylcholine-specific IgG2c failed to protect rats against intestinal infection with T. "
07/01/2006 - "Ex vivo high-resolution magic angle spinning (HRMAS) and 1H MRS of metabolite extracts revealed a significant reduction in phosphocholine and glycerophosphocholine in biopsies of ZD6126-treated tumors, confirming in vivo tCho response. "
01/07/2010 - "Nuclear magnetic resonance (NMR)-based metabolomic studies of human tumors have identified a marked increase in the intracellular concentration of phosphocholine relative to normal tissues. "
09/01/2003 - "Several (31)P MRS studies in tumors in vivo have shown that levels of phosphocholine (PC) and other phosphomonoesters (PME) and phosphodiesters (PDE) are useful prognostic or early-response indicators. "
11/01/2013 - "We demonstrated here that the phosphorylcholine-modified polyplexes can be explored as effective gene vector for selective uptake and high transfection of cancer cells. "
11/01/2013 - "Bioinspired phosphorylcholine-modified polyplexes as an effective strategy for selective uptake and transfection of cancer cells."
09/01/1984 - "CRP reacts with the phosphocholine moiety of pneumococcal cell wall C-polysaccharide, and this reaction can lead to complement activation in vitro and protection against pneumococcal infection in vivo. "
12/14/2012 - "We conclude that the phosphocholine-binding pocket on CRP is necessary for CRP-mediated initial protection of mice against lethal pneumococcal infection."
06/01/2007 - "CRP binds to phosphocholine in the Streptococcus pneumoniae cell wall and provides innate defense against pneumococcal infection. "
10/01/2002 - "Phosphorylcholine (PC), an epitope present on the cell-wall C-polysaccharide of all pneumococcal serotypes, is capable of eliciting a protective antibody response to pneumococcal infection in mice and provides an attractive model system for understanding the immune response generated by peptide mimics. "
04/01/1993 - "No protection against types 6A and 14 pneumococcal infection could be demonstrated neither with mouse monoclonal antibodies against C-Ps, specific for phosphorylcholine (PC) or for C-Ps backbone, nor for polyclonal rabbit immunsera against C-Ps. "
08/07/2007 - "The present study evaluated the effect of phosphorylcholine (PC) immunization on the extent of experimental atherosclerosis. "
08/07/2007 - "Phosphorylcholine-targeting immunization reduces atherosclerosis."
04/01/2009 - "Natural antibodies specific for phosphorylcholine (anti-PC) have been implicated as protective factors in atherosclerosis. "
01/01/2012 - "We have reported that anti-phosphorylcholine (anti-PC) IgM is a protection marker for human cardiovascular disease (CVD) and atherosclerosis. "
01/01/2010 - "Low level natural antibodies against phosphorylcholine: a novel risk marker and potential mechanism in atherosclerosis and cardiovascular disease."
|5.||Prostatic Neoplasms (Prostate Cancer)
07/05/2010 - "Phosphocholine carbamate analogue 5 is as effective against the prostate cancer cell lines as the corresponding phosphonocholine analogue 1. Cell death induced by 2'-(trimethylammonio)ethyl 4-hexadecyloxy-3(R)-N-methylcarbamoyl-1-butanephosphonate (carbamate analogue 2) appeared to be mediated by apoptosis, as assessed by caspase activation and loss of mitochondrial membrane potential. "
07/01/2011 - "This study demonstrates that high-grade prostate cancer shows significantly higher Ki-67 staining and concentrations of phosphocholine (PC) and glycerophosphocholine (GPC) than does low-grade prostate cancer (2.4 ± 2.8% versus 7.6 ± 3.5%, p < 0.005, and 0.671 ± 0.461 versus 1.87 ± 2.15 mmolal, p < 0.005, respectively). "
05/22/2012 - "More specifically, a decreased glycerophosphocholine (GPC) to phosphocholine (PC) ratio was reported in breast, ovarian, and prostate cancers. "
12/01/2012 - "The spectral resolution enabled the separate detection of phosphocholine, phosphoethanolamine, inorganic phosphate, and other metabolites that could play an important role in the characterization of prostate cancer."
06/01/2014 - "We investigated PC3 prostate cancer, MCF-7 breast cancer and A375 melanoma cells, and determined that, consistent with previous studies, MRS-detectable levels of phosphocholine decreased significantly in all cell lines (to 63%, 50% and 18% of the control, respectively) following MEK inhibition with U0126. "
|2.||Immunoglobulin M (IgM)
|10.||N-acetylaspartate (N-acetyl aspartate)
|3.||Vegetarian Diet (Vegetarianism)
|4.||Middle Ear Ventilation (Tympanostomy)