|1.||Li, Xu: 1 article (06/2013)|
|2.||Chen, Peng: 1 article (06/2013)|
|3.||Teng, Maikun: 1 article (06/2013)|
|4.||Li, Jianzhong: 1 article (06/2013)|
|5.||Ma, Jin: 1 article (06/2013)|
|6.||de Brouwer, Arjan P M: 1 article (12/2011)|
|7.||Christodoulou, John: 1 article (12/2011)|
|8.||Duley, John A: 1 article (12/2011)|
05/21/1984 - "The concentration of PRPP (phosphoribosyl pyrophosphate) measured in tumor cells grown in monolayer showed a large variation with the various harvesting methods examined, including trypsinization. "
12/01/1988 - "Results indicate that L-histidinol had no effect on the phosphoribosyl pyrophosphate levels in tumor, the activation of FUra to nucleotides or levels of free 5-fluorodeoxyuridine monophosphate in either tumor or bone marrow. "
12/14/1977 - "Although uridine was cleaved at approximately the same rate as inosine, as judged by lactate accumulation, concentrations of ribose 1-phosphate that accumulated were only approximately 0.06 mumol/ml. Ribose 1-phosphate accumulation in tumor cells incubated with inosine was dependent on the phosphate concentration of the medium up to at least 25 mM. Ribose 1-phosphate formed from inosine was readily converted both to phosphoribosyl pyrophosphate and to lactate."
08/01/1977 - "The effects of orthophosphate concentration on the accumulation of lactate and of phosphoribosyl pyrophosphate and on concentrations of ribose 1-phosphate and ribose 5-phosphate in tumor cells incubated with glucose were also determined. "
10/01/1986 - "Concentration of phosphoribosyl pyrophosphate in renal hypertrophy. "
03/15/1986 - "Concentration of phosphoribosyl pyrophosphate in the kidney during development and in experimental diabetic hypertrophy."
04/01/1993 - "The content of phosphoribosyl pyrophosphate (PPRibP) and of intermediates involved in its synthesis has been measured in the livers of obese (ob/ob) mice 2 months and 3-4 months of age, a period of dynamic growth and marked hepatic hypertrophy and hyperplasia, and comparison made with the values found in the lean age-matched control groups. "
04/01/1988 - "The fall in renal phosphoribosyl pyrophosphate associated with early diabetic renal hypertrophy (7) was also lessened by administration of SMS 201-995. "
04/01/1988 - "The effect of a somatostatin analogue (SMS 201-995, Sandostatin) on the concentration of phosphoribosyl pyrophosphate and the activity of the pentose phosphate pathway in the early renal hypertrophy of experimental diabetes in the rat."
09/01/1978 - "AMP-pyrophosphorylase from leukemia leukocytes was inactivated after heating up to 65 degrees, which, at the same time, as distinct from the enzyme of normal leukocytes, proved to be reversibly reduced after incubation of the heated cell extracts with phosphoribosyl pyrophosphate. "
09/28/1995 - "The IMP dehydrogenase inhibitor mycophenolic acid antagonizes the CTP synthetase inhibitor 3-deazauridine in MOLT-3 human leukemia cells: a central role for phosphoribosyl pyrophosphate."
06/01/2013 - "The D52H missense mutation of PRS1 will lead to a conspicuous phosphoribosyl pyrophosphate content elevation in the erythrocyte of patients and finally induce hyperuricemia and serious gout. "
11/01/1986 - "The activities of erythrocyte phosphoribosyl pyrophosphate (PRPP) synthetase and glutathione reductase (GTR) were studied in 26 patients with primary gout who were receiving no treatment or treatment with either allopurinol or azapropazone, and compared with the activity in a group of healthy controls. "
|5.||Ehrlich Tumor Carcinoma
01/01/1996 - "Effect of methotrexate on the intracellular phosphoribosyl pyrophosphate level and glucose transport of Ehrlich ascites tumor cells in vitro."
01/01/1978 - "Effects of 5'-deoxyadenosine on phosphoribosyl pyrophosphate and purine nucleotide synthesis in Ehrlich ascites tumor cells in vitro."
|9.||3-Deazauridine (3 Deazauridine)