|1.||Escobar, Javier: 6 articles (03/2012 - 01/2009)|
|2.||Sastre, Juan: 6 articles (03/2012 - 01/2009)|
|3.||Pereda, Javier: 6 articles (03/2012 - 01/2009)|
|4.||López-Rodas, Gerardo: 5 articles (03/2012 - 01/2009)|
|5.||Sabater, Luis: 5 articles (01/2012 - 01/2009)|
|6.||Aparisi, Luis: 5 articles (01/2012 - 01/2009)|
|7.||Fessard, Valérie: 5 articles (04/2009 - 05/2003)|
|8.||Arduini, Alessandro: 4 articles (01/2012 - 01/2009)|
|9.||Sandoval, Juan: 4 articles (06/2010 - 01/2009)|
|10.||Wipf, Peter: 4 articles (12/2009 - 01/2003)|
|1.||Post-Traumatic Stress Disorders (PTSD)
|2.||Brain Diseases (Brain Disorder)
01/01/2014 - "Extension studies using tumors from another 96 patients discovered a large number of truncation mutations in tumor suppressors (TP53 and RB1), protein phosphatases (e.g., PTEN, PTPRB, PTPRD, and PTPRT), as well as chromatin remodeling genes (e.g., ASXL3, MLL2, and ARID2). "
06/01/2008 - "These studies provide us with new insights into the role of protein phosphatases in cancer initiation and maintenance."
07/01/2000 - "In the present study the influence of dephosphorylation by Ser/Thr protein phosphatases (PPases) on tumor cell adhesion was investigated. "
03/01/2015 - "Protein serine/threonine phosphatase 2A (PP2A) expression in A549 cancer cells was reduced by TGF-β1 but CDN restored it. "
04/01/2014 - "Furthermore, current challenges on the protein phosphatases field as new targets to cancer therapy will be addressed. "
12/10/2005 - "Using a combination of fluorescence measurements of intracellular Ca(2+) ion concentration ([Ca(2+)](i)) and membrane potential we have investigated the sensitivity to serine/threonine phosphatase inhibition of Ca(2+) entry stimulated by activation of the Ca(2+) release-activated Ca(2+) (CRAC) entry pathway in rat basophilic leukemia cells. "
12/01/1994 - "Multiple apoptotic death types triggered through activation of separate pathways by cAMP and inhibitors of protein phosphatases in one (IPC leukemia) cell line."
06/01/2013 - "Although many studies established a relationship between protein phosphatases and leukemia, little is known about the role of this group of proteins in AML. "
01/01/2007 - "In this study, we show that constitutively active protein phosphatase 2A (PP2A), which is a serine/threonine phosphatase, is essential for T leukemia cell survival. "
06/24/1999 - "Apoptosis and mitotic arrest are two independent effects of the protein phosphatases inhibitor okadaic acid in K562 leukemia cells."
|5.||Melanoma (Melanoma, Malignant)
03/01/2014 - "Recent whole genome melanoma sequencing studies have identified recurrent mutations in the gene encoding the catalytic subunit of serine/threonine phosphatase 6 (PPP6C/PP6C). "
09/25/2014 - "However, little is known about protein phosphatases that dephosphorylate and thereby inactivate it in melanoma cells. "
12/01/2001 - "As PP2A is known to be a major cellular serine-threonine phosphatase, and has been implicated not only in the regulation of cell growth and division but also in the control of gene transcription and growth factor signal transduction, alterations in the pattern of the regulatory subunits may affect substrate specificity and subcellular localization of the PP2A holoenzyme in melanoma cells."
09/01/2012 - "Among the newly identified cancer genes was PPP6C, encoding a serine/threonine phosphatase, which harbored mutations that clustered in the active site in 12% of sun-exposed melanomas, exclusively in tumors with mutations in BRAF or NRAS. "
01/01/1999 - "In the present study, the significance of protein tyrosine phosphatases (PTP) and ser/thr protein phosphatases (PP) in alpha4beta1 and alpha5beta1 integrin-mediated mouse melanoma B16F1 cell anchorage and migration on fibronectin was characterized using phosphatase inhibitors. "
|6.||Protein Kinase C
|3.||Vasectomy (Vas Occlusion)
|4.||Transplantation (Transplant Recipients)
|5.||Drug Therapy (Chemotherapy)