|1.||Jan, Chung-Ren: 21 articles (12/2014 - 03/2002)|
|2.||Chou, Chiang-Ting: 14 articles (12/2014 - 07/2005)|
|3.||Jacobson, Kenneth A: 9 articles (05/2014 - 01/2002)|
|4.||Chang, Hong-Tai: 9 articles (10/2013 - 03/2002)|
|5.||Liang, Wei-Zhe: 8 articles (12/2014 - 11/2011)|
|6.||Kuo, Chun-Chi: 8 articles (12/2014 - 06/2010)|
|7.||Tsai, Jeng-Yu: 8 articles (02/2014 - 01/2009)|
|8.||Huang, Jong-Khing: 8 articles (12/2013 - 02/2003)|
|9.||Lo Vasco, Vincenza Rita: 7 articles (08/2014 - 07/2010)|
|10.||Flores-Díaz, Marietta: 7 articles (04/2014 - 12/2003)|
03/01/1992 - "However, whereas a proportion of wild-type organisms survive this early mechanism of defense to give rise to progressive infection, the phospholipase C-negative organisms are totally eliminated. "
11/01/2004 - "In this investigation, a differential display approach was applied to isolate soybean genes that are transcriptionally up-regulated by the inhibition of phosphoinositide-specific phospholipase C (PI-PLC) activity and to study if the transcription of those genes is altered following Psg infection. "
12/15/1992 - "This study has examined the effects of vaccinia virus infection on phospholipase C activity. "
05/01/2014 - "CVA9 infection is dependent on phospholipase C at the start of infection, whereas Rac1 is especially important between 1 and 3 h p.i., when the virus is in endosomes. "
01/01/2012 - "US28 is a potent activator of phospholipase C during HCMV infection of clinically relevant target cells."
05/01/2013 - "In this study, the immunogenicity and protective efficacy of the C-terminal domain (CP251-370) of the toxin and phospholipase C (PLC; CB, 372 residues) of Clostridum bifermentans isolated from cases of clostridium necrosis were examined. "
06/01/1996 - "It produces the alpha toxin (phospholipase C), which can induce spontaneous tissue necrosis. "
10/01/2006 - "In the presence of a phospholipase C antagonist, U73122, there was significant inhibition of the S1P protective effects against apoptosis/necrosis. "
01/01/2014 - "Mycobacterium tuberculosis expressing phospholipase C subverts PGE2 synthesis and induces necrosis in alveolar macrophages."
07/01/2003 - "All these results suggest that CM caused the cell death mode switch from necrosis to apoptosis through phospholipase C- and protein kinase C-mediated mechanisms."
02/01/2013 - "We report, for the first time, that acute hypoxia significantly enhances phospholipase C (PLC) activity in mouse resistance pulmonary arteries (PAs), but not in mesenteric arteries. "
12/20/2002 - "Activation of the neuroprotective ERK signaling pathway by fructose-1,6-bisphosphate during hypoxia involves intracellular Ca2+ and phospholipase C."
04/01/1999 - "Hypoxia increases the phosphoinositide-specific phospholipase C (PLC) activity in the carotid body. "
11/02/2001 - "Neuroprotection and intracellular Ca2+ modulation with fructose-1,6-bisphosphate during in vitro hypoxia-ischemia involves phospholipase C-dependent signaling."
11/02/2001 - "The phospholipase C inhibitor U73122 prevented FBP-induced increases in [Ca2+]i and eliminated FBP's ability to stabilize [Ca2+]i and increase survival during anoxia. "
09/01/2013 - "monocytogenes LII strains, 10403S and EGDe, and compared the flagellar motility, phospholipase C production, hemolysis, and intracellular growth of the mutants and their respective wild types. "
07/01/1994 - "The product obtained by gene engineering methods was found to possess the biological activity of the natural product: it induced the hemolysis of sheep red blood cells in the presence of equi factor of Rhinococcus equi and inhibited the hemolytic activity of Staphylococcus aureus beta-hemolysin (phospholipase C). "
09/01/1993 - "Of all toxins produced by the bacterium, phospholipase C (PLC) is believed to be the most likely cause of hemolysis. "
02/01/1983 - "The peak of hemolysis normally observed in the untreated erythrocytes at the range between 50 and 100 mOsM shifted to 160 to 200 mOsM with the progress of sphingomyelin hydrolysis by phospholipase C of C. "
02/01/1983 - "Hemolysis was shown to be due to phospholipase C activity by using the chromogenic substrate p-nitrophenylphosphorylcholine. "
|5.||Cystic Fibrosis (Mucoviscidosis)
12/20/2003 - "Rescue of defective pancreatic secretion in cystic-fibrosis cells by suppression of a novel isoform of phospholipase C."
04/28/1989 - "Increased phosphoinositide breakdown by phospholipase C in erythrocyte membranes from patients with cystic fibrosis."
01/01/2000 - "Patients with cystic fibrosis are severely affected by an infection with Pseudomonas aeruginosa, a microbe known to synthesize phospholipase C. "
04/27/2015 - "Bacterial phospholipases C as vaccine candidate antigens against cystic fibrosis respiratory pathogens: the Mycobacterium abscessus model."
11/01/1993 - "[Serodiagnosis of Pseudomonas aeruginosa infections in mucoviscidosis: comparative study of Western blotting, ELISA exotoxin A and ELISA phospholipase C]."
|1.||Protein Kinase C
|2.||1- (6- ((3- methoxyestra- 1,3,5(10)- trien- 17- yl)amino)hexyl)- 1H- pyrrole- 2,5- dione
|4.||Proteins (Proteins, Gene)
|6.||Membrane Proteins (Integral Membrane Proteins)
|3.||Drug Therapy (Chemotherapy)
|4.||Coronary Artery Bypass (Coronary Artery Bypass Surgery)