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Phosphoenolpyruvate Carboxykinase (GTP)

An enzyme of the lyase class that catalyzes the conversion of GTP and oxaloacetate to GDP, phosphoenolpyruvate, and carbon dioxide. This reaction is part of gluconeogenesis in the liver. The enzyme occurs in both the mitochondria and cytosol of mammalian liver. (From Dorland, 27th ed) EC 4.1.1.32.
Also Known As:
GTP-Dependent Phosphoenolpyruvate Carboxykinase; Carboxykinase, GTP-Dependent Phosphoenolpyruvate; GTP Dependent Phosphoenolpyruvate Carboxykinase; Phosphoenolpyruvate Carboxykinase, GTP-Dependent; GTP:oxaloacetate carboxy-lyase (transphosphorylating)
Networked: 11 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Perales, José C: 1 article (02/2006)
2. Bartrons, Ramon: 1 article (02/2006)
3. Gómez-Valadés, Alicia G: 1 article (02/2006)
4. Boada, Jordi: 1 article (02/2006)
5. Vidal-Alabró, Anna: 1 article (02/2006)
6. Molas, Maria: 1 article (02/2006)
7. Bermúdez, Jordi: 1 article (02/2006)

Related Diseases

1. Hepatocellular Carcinoma (Hepatoma)
2. Adenoviridae Infections (Adenovirus Infections)
3. Starvation
4. Hyperglycemia
5. Hyperthyroidism

Related Drugs and Biologics

1. Chloramphenicol O-Acetyltransferase (Chloramphenicol Acetyltransferase)
2. Phosphoenolpyruvate Carboxykinase (GTP)
3. Insulin (Novolin)
4. Oxaloacetate
5. Complementary DNA (cDNA)
6. Vanadates (Orthovanadate)
7. Poly Adenosine Diphosphate Ribose
8. Phorbol Esters
9. Norepinephrine (Noradrenaline)
10. Ligases

Related Therapies and Procedures

1. Adrenalectomy