3-Deoxy-7-Phosphoheptulonate Synthase (3 Deoxy 7 Phosphoheptulonate Synthase)

An enzyme that catalyzes the formation of 7-phospho-2-keto-3-deoxy-D-arabinoheptonate from phosphoenolpyruvate and D-erythrose-4-phosphate. It is one of the first enzymes in the biosynthesis of TYROSINE and PHENYLALANINE. This enzyme was formerly listed as EC 4.1.2.15.

Also Known As:

3 Deoxy 7 Phosphoheptulonate Synthase; 3-Deoxy-Arabino-Heptulosonate-7-Phosphate Synthase; 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase; DAH7-P; 2 Dehydro 3 Deoxyphosphoheptonate Aldolase; 3 Deoxy Arabino Heptulosonate 7 Phosphate Synthase; 3 Deoxy D Arabino Heptulosonate 7 Phosphate Synthase; 3 Deoxyarabinoheptulosonate 7 Phosphate Synthetase; Aldolase, 2-Dehydro-3-Deoxyphosphoheptonate; Aldolase, Phospho-2-Keto-3-Deoxyheptonate; Phospho 2 Keto 3 Deoxyheptonate Aldolase; Synthase, 3-Deoxy-7-Phosphoheptulonate; Synthase, 3-Deoxy-Arabino-Heptulosonate-7-Phosphate; Synthase, 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate; Synthase, DAHP; Synthetase, 3-Deoxyarabinoheptulosonate-7-Phosphate; 2-Dehydro-3-Deoxyphosphoheptonate Aldolase; 3-Deoxyarabinoheptulosonate-7-Phosphate Synthetase; DAHP Synthase; Phospho-2-Keto-3-Deoxyheptonate Aldolase; 2-Dehydro-3-deoxy-D-arabino-heptonate-7-phosphate D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating)

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Alkyl and Aryl Transferases: 180
      - 3-Deoxy-7-Phosphoheptulonate Synthase: 3

Experts

1.	Alkan, Noam: 1 article (01/2020)
2.	Elad, Yigal: 1 article (01/2020)
3.	Galili, Gad: 1 article (01/2020)
4.	Galsurker, Ortal: 1 article (01/2020)
5.	Hatan, Erel: 1 article (01/2020)
6.	Kumar, Varun: 1 article (01/2020)
7.	Lewinsohn, Efraim: 1 article (01/2020)
8.	Nisim-Levi, Ada: 1 article (01/2020)
9.	Oliva, Moran: 1 article (01/2020)
10.	Oren-Shamir, Michal: 1 article (01/2020)

Related Diseases

1.	Wounds and Injuries (Trauma) 08/01/1995 - "No alteration in the wound induction of DAHP synthase gene expression was observed in transgenic potato tubers containing the chimeric sense construct. " 08/01/1995 - "Impaired Wound Induction of 3-Deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) Synthase and Altered Stem Development in Transgenic Potato Plants Expressing a DAHP Synthase Antisense Construct." 08/01/1995 - "Some, but not all, of the transgenic plants expressing antisense DAHP synthase RNA showed reduced levels of wound-induced DAHP synthase enzyme activity, polypeptide, and mRNA 12 and 24 h after wounding. "
2.	Infections 01/01/2020 - "Arabidopsis, petunia and tomato plants were enriched with Phe by either overexpressing a feedback-insensitive E.coli DAHP synthase (AroG*), or by spraying or drenching detached leaves or whole plants with external Phe, prior to infection with B. "
3.	Dehydration (Water Stress) 06/01/2011 - "Our results indicate that water stress resulted in decreased shikimate pathway (DAHP synthase, shikimate dehydrogenase, phenylalanine ammonium lyase, cinnamate 4-hydroxylase, 4-coumarate CoA ligase) and phenolic compounds (caffeoylquinic acid derivatives, quercetin and kaempferol) in the cultivars more sensitive to water stress. "

Related Drugs and Biologics

1.	Ammonium Compounds
2.	Trans-Cinnamate 4-Monooxygenase (Trans Cinnamate 4 Monooxygenase)
3.	Messenger RNA (mRNA)
4.	RNA (Ribonucleic Acid)
5.	Quercetin
6.	Phenylalanine (L-Phenylalanine)
7.	Peptides (Polypeptides)
8.	Lyases
9.	Ligases (Synthetase)
10.	Enzymes