|1.||Shen, Jie: 13 articles (01/2015 - 07/2010)|
|2.||Liang, Xin: 10 articles (03/2013 - 06/2004)|
|3.||Pauluhn, Jürgen: 8 articles (02/2015 - 08/2006)|
|4.||Zhang, Lin: 8 articles (09/2014 - 07/2010)|
|5.||Hai, Chun-xu: 8 articles (03/2013 - 06/2004)|
|6.||Zhang, Xiao-di: 7 articles (03/2013 - 08/2005)|
|7.||Sciuto, Alfred M: 7 articles (11/2005 - 05/2002)|
|8.||Qin, Xu-jun: 6 articles (03/2013 - 06/2004)|
|9.||Chen, Hong-li: 6 articles (03/2013 - 06/2004)|
|10.||Liu, Rui: 6 articles (03/2013 - 06/2004)|
07/01/2004 - "Direct antipermeability effects of AMIN-induced upregulation of cAMP on cellular contraction may also be important in protection against phosgene-induced lung injury. "
07/01/1997 - "Direct antipermeability effects of cAMP on cellular contraction may also be important in protection against phosgene-induced lung injury."
07/01/2004 - "Both in situ and in vivo models were used to assess the efficacy of postexposure treatment of phosgene-induced lung injury using clinically existing drugs. "
09/01/2001 - "Temporal changes in these physiological indicators of lung injury may help to explain why past exposures to phosgene required lengthy hospitalization."
10/01/2013 - "The purpose of this study is to investigate the molecular mechanisms of phosgene-induced lung injury. "
01/01/2013 - "In the present study, we aim to investigate the protective effects of EP on phosgene-induced pulmonary edema and the underlying mechanisms. "
06/01/2010 - "This study discovered that intraperitoneal administration of NAC significantly alleviated phosgene-induced pulmonary edema, as confirmed by decreased lung wet to dry weight ratio and oxidative stress markers. "
01/01/2006 - "The purpose of this study was to investigate cell of apoptosis in pulmonary edema mice induced by phosgene. "
08/01/2005 - "To study apoptosis of pulmonary epithelial cells and endothelial cells in mice with pulmonary edema induced by phosgene exposure. "
12/01/2015 - "Phosgene's primary mode of action is as a pulmonary irritant characterized by its early latent phase where life-threatening, non-cardiogenic pulmonary edema is typically observed 6-24 h post-exposure. "
|3.||Acute Lung Injury
07/01/2010 - "Multiple small and large animal studies have been performed to examine potential treatments of phosgene-induced acute lung injury, but many of these used isolated organ models, pretreatment regimens, or clinically improbable doses. "
07/01/2010 - "This review aims to examine all published studies concerning potential treatments for phosgene-induced acute lung injury and incorporate them into up-to-date clinical guidance. "
02/01/2009 - "The aim of the present study was to investigate the correlation between sPLA(2)-IIA activity and the severity of phosgene-induced acute lung injury. "
03/01/2007 - "This study aims to examine the pathophysiological changes seen with low tidal volume ventilation (protective ventilation (PV)) strategies compared to conventional ventilation (CV), in a model of phosgene-induced acute lung injury. "
12/01/2015 - "To develop an inhaled phosgene acute lung injury (ALI) model in C57BL/6 mice that can be used to screen potential medical countermeasures. "
03/01/2013 - "The purpose of this study was to investigate the protective effects of CAPE on phosgene-induced ALI and identify the mechanism, in which oxidative stress and inflammation were involved. "
05/01/1997 - "At 0.2 ppm phosgene, terminal bronchiolar thickening and inflammation appeared to be more prominent when compared to the 0.1 ppm group and changes in alveolar parenchyma were minimal. "
05/01/1997 - "Small but clearly apparent terminal bronchiolar thickening and inflammation were evident with 0.1 ppm phosgene at both 4 and 12 weeks. "
05/01/2012 - "A first aid kit has thus been developed for providing immediate relief from chemical and biological warfare agents (FAKCBW) with the objective of easy detection, personal decontamination, antidote for chemical warfare agents (like nerve agents, sulphur mustard, phosgene, cyanide, radiation exposure and bacterial agents), along with basic medication aid for pain, fever and inflammation. "
01/01/1996 - "Phosgene (COCl2) is a colorless oxidant gas which is heavier than air and the lethal exposure dose (LC50) in humans is 500 ppm/min. This gas was originally manufactured as an agent for chemical warfare during World War I and there had been a great deal of studies on phosgene poisoning during the early years of industrial use. "
08/01/1992 - "[Clinical and radiological studies on 15 cases of acute phosgene poisoning]."
01/01/1969 - "[The early phases of phosgene poisoning in light microscopic, electron-microscopic and roentgenological studies]."
06/01/1948 - "Studies on experimental phosgene poisoning; infusions in the treatment of experimental phosgene poisoning."
04/01/1948 - "Studies on experimental phosgene poisoning; pulmonary artery pressure in phosgene-poisoned cats."
|2.||urinastatin (MR 20)
|3.||Chemical Warfare Agents
|5.||Matrix Metalloproteinase 9 (Gelatinase B)
|6.||Arachidonic Acid (Vitamin F)
|7.||5,8,11,14-Eicosatetraynoic Acid (5,8,11,14 Eicosatetraynoic Acid)
|2.||First Aid (Aids, First)
|4.||Investigational Therapies (Experimental Therapy)
|5.||Positive-Pressure Respiration (PEEP)