|1.||Pramanik, A: 2 articles (11/2003 - 11/2001)|
|2.||McKoy, J: 2 articles (11/2003 - 11/2001)|
|3.||Moore, C W: 2 articles (11/2003 - 11/2001)|
|4.||Blatzer, Michael: 1 article (01/2013)|
|5.||Schrettl, Markus: 1 article (01/2013)|
|6.||Abt, Beate: 1 article (01/2013)|
|7.||Gsaller, Fabio: 1 article (01/2013)|
|8.||Haas, Hubertus: 1 article (01/2013)|
|9.||Lindner, Herbert: 1 article (01/2013)|
|10.||Blom, Eric: 1 article (07/2010)|
01/31/1963 - "Mechanism of action of phleomycin, a tumor-inhibitory antibiotic."
03/01/1965 - "EFFECT OF PHLEOMYCIN ON DNA POLYMERASE OF TUMOR ORIGIN."
04/01/1984 - "Significant and often substantial enhancement of the antitumor properties of several individual phleomycins , by co- administration via intraperitoneal injection of a number of purine analogues, is demonstrated in rats and mice having three diverse tumors. "
01/01/2005 - "Zeocin, a member of the bleomycin/phleomycin family of antibiotics, is known to bind DNA and to induce apoptosis in cervical cancer cells, but the mechanism underlying this apoptotic response is poorly understood. "
04/01/1983 - "In our laboratory, we have studied the mechanism of action of tumor-inhibitory antibiotics, including bleomycin, phleomycin, adriamycin, aclarubicin, neothramycin, macromomycin, auromomycin, chartreusin, pluramycin, neopluramycin, xanthomycin A, angustmycins A and C, blasticidin S and phenomycin. "
07/07/2010 - "Whilst interaction of TPR7-mutated FANCG with FANCF does appear to be reduced in NM3, FANCD2 is monoubiquitylated suggesting that sub-optimal interactions of FANCG in the core complex and the D1-D2-G-X3 complex are responsible for the observed MMC- and phleomycin-hypersensitivity, rather than a defect in FANCD2 monoubiquitylation. "
04/26/2009 - "When exposed to phleomycin or MMC, the mitochondrial mutant cells again showed hypersensitivity and decreased mitotic indices compared to normal cells. "
11/01/2003 - "Mutational alteration of the BLM5 gene of the model eukaryote, Saccharomyces cerevisiae, confers extreme hypersensitivities to lethal effects of ionizing radiation, anticancer bleomycins and structurally-related phleomycins. "
11/01/2001 - "Mutational alteration of the BLM3 gene in Saccharomyces cerevisiae confers hypersensitivities to lethal effects of ionizing radiation, anticancer bleomycins and structurally-related phleomycins. "
07/07/2010 - "Expression of mutated TPR1, TPR2, TPR5 and TPR6 in Chinese hamster fancg mutant NM3 fails to functionally complement its hypersensitivities to mitomycin C (MMC) and phleomycin and fails to restore FANCD2 monoubiquitylation. "
|3.||Chromosome Aberrations (Chromosome Abnormalities)
03/01/1969 - "Phleomycin-induced mitotic inhibition and chromosomal abnormalities in cultured human leucocytes."
04/26/2009 - "Here, ionizing radiation, phleomycin and mitomycin C (MMC) were used to induce structural chromosomal aberrations in Leber's and Leigh's cells to investigate how these mitochondrial mutations affect the cell's DNA repair processes. "
11/01/1982 - "The in vitro effects (strand breakage) of phleomycin and bleomycin are compared with induction of chromosomal aberrations in human lymphocytes and oocytes of Drosophila melanogaster."
01/01/1995 - "Nevertheless, lysates from phleomycin-treated cells were considerably more cytotoxic than lysates from bleomycin-treated cells or freshly prepared bleomycin, consistent with the higher effectiveness of phleomycin than bleomycin in producing chromosomal breaks, genetic changes, and cell killing."
01/01/1995 - "Genetic changes and bioassays in bleomycin- and phleomycin-treated cells, and their relationship to chromosomal breaks."
12/01/1988 - "In vivo (cellular) repair of chromatin damage was comparable (approximately 90% in 1 h) after cells were exposed to low drug concentrations which produced similar numbers of chromatin breaks, and thus also does not account for the higher chromosomal breakage caused by phleomycin than bleomycin at low doses. "
|3.||DNA (Deoxyribonucleic Acid)
|6.||Anti-Bacterial Agents (Antibiotics)
|7.||Fanconi Anemia Complementation Group G Protein
|8.||Untranslated Regions (Untranslated Region)