HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Phenylalanine Hydroxylase (Phenylalanine 4 Monooxygenase)

An enzyme of the oxidoreductase class that catalyzes the formation of L-TYROSINE, dihydrobiopterin, and water from L-PHENYLALANINE, tetrahydrobiopterin, and oxygen. Deficiency of this enzyme may cause PHENYLKETONURIAS and PHENYLKETONURIA, MATERNAL. EC 1.14.16.1.
Also Known As:
Phenylalanine 4 Monooxygenase; Phenylalanine 4-Hydroxylase; Phenylalanine 4-Monooxygenase; 4-Hydroxylase, Phenylalanine; 4-Monooxygenase, Phenylalanine; Hydroxylase, Phenylalanine; Phenylalanine 4 Hydroxylase; L-Phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)
Networked: 878 relevant articles (7 outcomes, 39 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Blau, Nenad: 27 articles (01/2022 - 03/2003)
2. Thöny, Beat: 19 articles (01/2022 - 12/2005)
3. Harding, Cary O: 15 articles (01/2022 - 11/2003)
4. Dobrowolski, Steven F: 14 articles (01/2022 - 07/2007)
5. Vockley, Jerry: 13 articles (01/2022 - 02/2014)
6. Martinez, Aurora: 12 articles (01/2021 - 10/2006)
7. Muntau, Ania C: 11 articles (01/2021 - 07/2008)
8. Feillet, François: 10 articles (01/2022 - 03/2006)
9. Shen, Nan: 10 articles (01/2022 - 03/2016)
10. Burlina, Alberto: 9 articles (11/2021 - 01/2008)

Related Diseases

1. Phenylketonurias (Phenylketonuria)
2. Hepatocellular Carcinoma (Hepatoma)
3. Schizophrenia (Dementia Praecox)
4. Treatment-Resistant Depressive Disorder
5. Chronic Kidney Failure (Chronic Renal Failure)

Related Drugs and Biologics

1. sapropterin (tetrahydrobiopterin)
2. Phenylalanine (L-Phenylalanine)
3. Amino Acids
4. Enzymes
5. DNA (Deoxyribonucleic Acid)
6. Proteins (Proteins, Gene)
7. Fenclonine (p-Chlorophenylalanine)
8. Antibodies
9. Peptides (Polypeptides)
10. RNA Splice Sites

Related Therapies and Procedures

1. Therapeutics
2. Diet Therapy (Therapy, Diet)
3. Subcutaneous Injections
4. Drug Therapy (Chemotherapy)
5. Oral Administration