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Phenylethanolamine N-Methyltransferase

A methyltransferase that catalyzes the reaction of S-adenosyl-L-methionine and phenylethanolamine to yield S-adenosyl-L-homocysteine and N-methylphenylethanolamine. It can act on various phenylethanolamines and converts norepinephrine into epinephrine. (From Enzyme Nomenclature, 1992) EC 2.1.1.28.
Also Known As:
Noradrenalin N-Methyltransferase; Noradrenaline N-Methyltransferase; Norepinephrine Methyltransferase; Norepinephrine N-Methyltransferase; Methyltransferase, Norepinephrine; Noradrenalin N Methyltransferase; Noradrenaline N Methyltransferase; Norepinephrine N Methyltransferase; Phenethanolamine N Methyltransferase; Phenylethanolamine N Methyltransferase; Phenethanolamine N-Methyltransferase; S-Adenosyl-L-methionine:phenylethanolamine N-methyltransferase
Networked: 97 relevant articles (0 outcomes, 7 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Eisenhofer, Graeme: 3 articles (05/2022 - 08/2006)
2. Bechmann, Nicole: 2 articles (05/2022 - 11/2021)
3. Kimura, Noriko: 2 articles (03/2022 - 12/2021)
4. Isseroff, R Rivkah: 2 articles (01/2018 - 01/2009)
5. Rocke, David M: 2 articles (01/2018 - 01/2009)
6. Tai, T C: 2 articles (01/2018 - 09/2010)
7. Pacak, Karel: 2 articles (06/2017 - 08/2006)
8. Tatsuno, Ichiro: 2 articles (03/2016 - 02/2003)
9. Al-Sawalha, Nour: 2 articles (01/2016 - 02/2013)
10. Bond, Richard A: 2 articles (01/2016 - 02/2013)

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4. Hypoglycemia (Reactive Hypoglycemia)
5. Multiple Endocrine Neoplasia Type 2a (MEN 2)

Related Drugs and Biologics

1. Epinephrine (Adrenaline)
2. Enzymes
3. Catecholamines
4. Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)
5. Norepinephrine (Noradrenaline)
6. Proto-Oncogene Proteins c-ret
7. Dopamine beta-Hydroxylase
8. Dopamine (Intropin)
9. Messenger RNA (mRNA)
10. 7,8- dichloro- 1,2,3,4- tetrahydroisoquinoline

Related Therapies and Procedures

1. Surgical Instruments (Clip)
2. Vagotomy
3. Sympathectomy (Sympathectomies)
4. Nephrectomy
5. Hypophysectomy