Peripheral Nervous System Neoplasms

Neoplasms which arise from peripheral nerve tissue. This includes NEUROFIBROMAS; SCHWANNOMAS; GRANULAR CELL TUMORS; and malignant peripheral NERVE SHEATH NEOPLASMS. (From DeVita Jr et al., Cancer: Principles and Practice of Oncology, 5th ed, pp1750-1)
Also Known As:
Peripheral Nerve Neoplasms; Peripheral Nerve Neoplasms, Benign; Peripheral Nerve Neoplasms, Malignant; Peripheral Nerve Neoplastic Infiltration; Peripheral Nerve Tumors; Peripheral Nervous System Benign Neoplasms; Peripheral Nervous System Malignant Neoplasms; Neoplasm, Peripheral Nerve; Neoplasms, Peripheral Nerve; Nerve Neoplasm, Peripheral; Nerve Neoplasms, Peripheral; Nerve Tumor, Peripheral; Nerve Tumors, Peripheral; Peripheral Nerve Neoplasm; Peripheral Nerve Tumor; Tumor, Peripheral Nerve; Tumors, Peripheral Nerve
Networked: 33 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Related Diseases

1. Prostatic Neoplasms (Prostate Cancer)
2. Lung Neoplasms (Lung Cancer)
3. Hodgkin Disease (Hodgkin's Disease)
4. Neurofibroma
5. Neoplasms (Cancer)


1. Perry, Arie: 2 articles (12/2005 - 02/2004)
2. Gutmann, David H: 2 articles (12/2005 - 02/2004)
3. Duranyildiz, Derya: 1 article (01/2013)
4. Serilmez, Murat: 1 article (01/2013)
5. Dizdar, Yavuz: 1 article (01/2013)
6. Soydinc, Hilal Oguz: 1 article (01/2013)
7. Yasasever, Ceren Tilgen: 1 article (01/2013)
8. Yasasever, Vildan: 1 article (01/2013)
9. Bilgin, Elif: 1 article (01/2013)
10. Sugihara, Shinsuke: 1 article (09/2012)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Peripheral Nervous System Neoplasms:
1. Phosphopyruvate Hydratase (Enolase)IBA
2. S100 Proteins (S 100 Protein)IBA
3. Ethylnitrosourea (N-Ethyl-N-nitrosourea)IBA
01/01/1990 - "Immunohistochemical characterization of rat central and peripheral nerve tumors induced by ethylnitrosourea."
01/01/1973 - "Biological characteristics of peripheral nerve tumors induced with ethylnitrosourea."
10/01/1999 - "Peripheral nerve tumors (PNT) and melanomas induced transplacentally on day 14 of gestation in Syrian golden hamsters by N-nitrosoethylurea were analyzed for activated oncogenes by the NIH 3T3 transfection assay, and for mutations in the neu oncogene by direct sequencing, allele-specific oligonucleotide hybridization, MnlI restriction-fragment-length polymorphism, single-strand conformation polymorphism, and mismatch amplification mutation assays. "
01/01/1989 - "The majority of spontaneous peripheral nerve tumors were of cystic histological structure identical to that of cystic neurinomas induced in rats by ethylnitrosourea and almost all of these tumors were S-100 protein positive. "
01/01/1990 - "Ethylnitrosourea-induced central and peripheral nerve tumors in Sprague-Dawley rats were tested for GFAP (Glial Fibrillary Acidic Protein), S-100 protein, NSE (Neuron Specific Enolase) and Anti-Leu 7 (HNK-1) immunoreactivity utilizing the ABC method (avidin-biotin-complex) for GFAP, S-100 protein and NSE, and the PAP method (peroxidase-antiperoxidase) for Anti-Leu 7. Peripheral nerve neurinomas were consistently positive for S-100 protein and consistently negative for GFAP and Anti-Leu 7. Neurinomas would occasionally exhibit positive staining for NSE (2 of 55 tumors). "
4. Neurofibromin 1 (Neurofibromin)IBA
5. Monophenol Monooxygenase (Tyrosinase)IBA
6. Formaldehyde (Formol)FDA Link
7. Dermatofibrosarcoma protuberansIBA
8. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
9. Integrin alpha6beta4IBA
10. Intercellular Signaling Peptides and Proteins (Growth Factors)IBA

Therapies and Procedures

1. Thoracoscopes
2. Radiotherapy
3. Biological Therapy
4. Amputation