|5.||Periodontal Diseases (Periodontal Disease)
|1.||Wennström, Jan L: 8 articles (09/2011 - 01/2002)|
|2.||Slots, J: 5 articles (06/2015 - 09/2000)|
|3.||Ylöstalo, Pekka: 4 articles (06/2015 - 04/2004)|
|4.||Potempa, Jan: 4 articles (01/2015 - 03/2005)|
|5.||Nishinoue, Norihide: 4 articles (01/2015 - 01/2009)|
|6.||Fukuda, Mitsuo: 4 articles (12/2014 - 01/2005)|
|7.||Noguchi, Toshihide: 4 articles (12/2014 - 01/2005)|
|8.||Sorsa, Timo: 4 articles (06/2010 - 10/2004)|
|9.||Mombelli, A: 4 articles (03/2005 - 06/2001)|
|10.||Jorgensen, M G: 4 articles (10/2004 - 09/2000)|
03/01/2002 - "unstimulated whole saliva flow rate (UWS) had increased, PI and periodontal pocket depth (PPD) were reduced, and general health and oral dryness and soreness had improved after using CHP. "
01/01/2015 - "Patients were stratified by periodontal pocket depth (PPD): normal oral status/mild PDD (PPD < 4 mm), moderate PDD (PPD 4-5 mm), and severe PDD (PPD ≥ 6 mm). "
12/01/2013 - "PPD changes after SRP were not affected by gingival biotype with either shallow or deep periodontal pockets. "
10/01/2013 - "This investigation extends our previous dental data collection pilot study with the following main aims: to gain insight into the periodontal complaints that dentists in the UK treat using individualised homeopathic prescription; to record patient-assessed change in severity of treated complaint (acute or chronic); to determine periodontal pocket depth (PPD). "
05/01/2012 - "In the long term, we found that SRP + NDL treatment of periodontal pockets was more effective than SRP alone in reducing PPD, CAL, GI, and GCF values."
01/01/1990 - "[Efficacy of chlorhexidine on germ spectrum of periodontal pockets--an in vitro study]."
10/01/1990 - "Self-performed subgingival irrigation with 0.2% chlorhexidine is a simple method of treating isolated, deep periodontal pockets which do not respond favorably to conventional treatment techniques. "
09/01/1986 - "Previous studies have shown that a 3-day exposure of the pocket flora to the sustained release of chlorhexidine significantly reduced the relative numbers of spirochetes and motile rods in periodontal pockets to negligible amounts. "
01/01/1982 - "The purposes of this study were to investigate the effect of direct application of chlorhexidine to periodontal pockets and the practicability of patient self-therapy using a technique of subgingival irrigation. "
01/01/2014 - "Absorbent points widely used in endodontic therapy were transformed into bioresorbable chlorhexidine delivery systems for the treatment of the periodontal pocket by preventing its recolonization by the subgingival microflora. "
|3.||Tetracycline (Achromycin)FDA LinkGeneric
07/03/2000 - "The clinical efficacy of this (test) formulation was compared to an identical tetracycline-devoid (control) formulation in nine periodontal pockets (>/=5 mm depth). "
01/01/2009 - "Effect of absorbent tetracycline-loaded membrane used in the reduction of periodontal pockets: an in vivo study."
01/01/2001 - "The pilot clinical study indicated a mean half-time of tetracycline in GCF of 28 min with confidence intervals of 21 to 34 min, although wide variation between the drug levels of individual periodontal pockets was seen. "
03/01/1997 - "Biodegradable microparticles for sustained delivery of tetracycline to the periodontal pocket: formulatory and drug release studies."
10/01/1992 - "The primary objective of this study was to evaluate the concentration and location of tetracycline hydrochloride in tissue adjacent to periodontal pockets treated with a tetracycline impregnated fiber. "
|4.||Doxycycline (Vibramycin)FDA LinkGeneric
11/01/1996 - "It was concluded that, for the beagle dogs with severely infected periodontal pockets in this study, treatment with subgingival doxycycline using the delivery system resulted in substantial improvement in periodontal health."
06/01/1988 - "The results of this study strongly suggest that surgery plus doxycycline effectively eliminate Aa from periodontal pockets. "
10/01/2004 - "Controlled-release doxycycline placed in moderate to deep periodontal pockets caused no significant additional reduction in the subgingival pathogenic microbiota compared to thorough Sc/Rp alone. "
01/01/2002 - "Treatment of periodontal pockets with doxycycline in beagles."
10/01/1998 - "The high concentration of drug available at the treated sites coupled with the relatively low levels in the saliva and almost non-existent levels in the serum indicate that this biodegradable controlled-release delivery system displays an appropriate pharmacokinetic profile for the delivery of doxycycline into periodontal pockets."
|5.||Metronidazole (Metric)FDA LinkGeneric
07/01/2005 - "The aim of our latest research was to test the efficacy of newly formulated preparation containing 25% metronidazole suspended in a lipogel in vitro--in anaerobic cultures isolated from the periodontal pockets, and in vivo--by the direct application into periodontal pockets. "
04/30/2015 - "The aim of this study was to develop sustained-release metronidazole films for periodontal pockets using a computer-aided statistical approach. "
05/01/2014 - "This study was performed to obtain prolonged drug release with biodegradable in situ forming implants for the local delivery of metronidazole to periodontal pockets. "
05/01/2014 - "In situ forming implants for the delivery of metronidazole to periodontal pockets: formulation and drug release studies."
09/01/1984 - "The purpose of this study was to develop a sustained release device containing metronidazole for insertion within periodontal pockets and to examine the release kinetics in vitro and in vivo. "
|6.||Minocycline (Cyclops)FDA LinkGeneric
01/01/2015 - "NIH3T3 cells were cultured and attached to the each slide, and the viability and proliferation of cells were observed; In vivo, 21 deep periodontal pockets were treated by periodontal surgery, and the exposed root surfaces were randomly conditioned with 2% minocycline-HCl paste or 0.9% saline. "
09/01/2008 - "After SRP, subjects received minocycline or placebo at the baseline, and at 3, 6, and 9 months at all sites with a periodontal pocket depth (PD) of >or= 6 mm. Moreover, two homologous teeth, initially PD >or= 6 mm, were clinically and microbially monitored by PCR at the baseline, and at 3, 6, 9, 12 and 24 months. "
01/01/2005 - "Microflora cultivable from minocycline strips placed in persisting periodontal pockets."
10/24/2003 - "The plaque samples were obtained from eight patients (eight periodontal pockets) before and 1 week after the local drug delivery of minocycline. "
07/01/2003 - "Local antibiotic application with minocycline ointment in periodontal pockets was beneficial as an ancillary treatment, especially during neutropenic periods."
10/01/1998 - "These studies provide the basis for understanding the oxygen tension in the periodontal pocket, which likely is a major determinant of the subgingival microflora. "
01/01/1994 - "The aim of this study was to assess the effect of repeated subgingival oxygen irrigations in previously untreated deep periodontal pockets. "
12/01/2010 - "However, little is known about how the host tissues respond to bacteria under differing oxygen tensions within the periodontal pocket. "
12/01/1983 - "[Assessment of hydrogen ion concentration and oxygen tension in the human gingival sulci and periodontal pockets]."
11/01/1983 - "Relationship between oxygen tension and subgingival bacterial flora in untreated human periodontal pockets."
|8.||Anti-Infective Agents (Microbicides)IBA
06/01/2001 - "Local delivery of antimicrobial agents in inflamed periodontal pocket has been shown to be effective in reducing periodontopathic microorganisms. "
03/01/2005 - "It is rather better to deliver antimicrobial agents directly into the periodontal pocket. "
01/01/2003 - "Hence, antimicrobial agents must be available at a sufficiently high concentration not only within the periodontal tissues, but also outside, in the environment of the periodontal pocket. "
03/01/1999 - "Controlled release delivery systems have become available for the sustained delivery of antimicrobial agents directly to the periodontal pocket. "
10/01/1996 - "The use of antimicrobial agents also promotes the emergence of bacterial drug resistance, both in the periodontal pocket and in the normal oral and intestinal microflora. "
|9.||Glycine (Aminoacetic Acid)FDA LinkGeneric
06/01/2007 - "Glycine powder air polishing (GPAP) has been shown to be significantly more effective in reducing the subgingival cultivable microflora in shallow periodontal pockets compared to curets and is safe when applied directly to root surfaces. "
04/01/2012 - "This study assesses efficacy and safety of subgingivally applied glycine powder air polishing (SubGPAP) in moderate-to-deep periodontal pockets. "
04/01/2012 - "Supragingivally applied glycine powder air polishing (SupraGPAP) has been shown to remove biofilms in shallow periodontal pockets. "
04/01/2012 - "Randomized controlled trial assessing efficacy and safety of glycine powder air polishing in moderate-to-deep periodontal pockets."
07/01/2005 - "Elevated concentrations of glycine were previously found in periodontal pockets and saliva of periodontitis patients and, therefore, we aimed to study the influence of glycine on PGE(2) production. "
09/01/1984 - "This study demonstrates that, by embedding metronidazole in ethyl cellulose, it is possible to obtain sustained release of the drug within the periodontal pocket for three days."
07/01/1991 - "The release of chlorhexidine from an ethyl cellulose-based dosage form (SRD) has been shown to be effective in the reduction of the flora associated with periodontal pockets as well as in reducing probing depths. "
04/01/1998 - "The present study compared the effectiveness of two antimicrobials, tetracycline and metronidazole, in reducing subgingival microorganisms in periodontal pockets using an ethyl cellulose strip as the delivery medium. "
10/01/2004 - "Although these devices differ with regard to ease of use, concentration of drug delivered and length of time high drug concentrations can be maintained, randomized clinical trials have shown that their use as an adjunctive treatment to scaling and root planing results in a significantly greater reduction of periodontal pocket depth and an average increase in clinical periodontal attachment level of about 0.8 mm. Gain in clinical attachment is greater in deeper pockets than in shallower pockets. "
12/01/2008 - "The bone density within periodontal pockets treated with beneficial bacteria improved significantly after 12 weeks, while this was non-significant for the control pockets, receiving a single root planing at baseline. "
01/01/2011 - "The experimental local drug-delivery system containing 2% whole turmeric gel can be effectively used as an adjunct to scaling and root planing and is more effective than scaling and root planing alone in the treatment of periodontal pockets."
09/01/2007 - "Open root planing following flap elevation resulted in a recovery rate of 85.4% and was effective for deep and refractory periodontal pockets. "
12/01/2014 - "The aim was to evaluate the efficacy of CHX varnish and gel as an adjunct to scaling and root planing (SRP) in reducing microbial count within moderate to deep periodontal pockets. "
06/01/2007 - "The purpose of this study was to assess the subgingival debridement efficacy of GPAP in periodontal pockets with various depths. "
09/01/2005 - "Conventional surgical approaches (e.g., flap debridement) continue to offer time-tested and reliable methods to access root surfaces,reduce periodontal pockets, and attain improved periodontal form/architecture. "
08/01/2005 - "To evaluate the clinical efficacy of (i) a single session of "full-mouth ultrasonic debridement" (Fm-UD) as an initial periodontal treatment approach and (ii) re-instrumentation of periodontal pockets not properly responding to initial subgingival instrumentation. "
08/01/2003 - "The findings from the present study do not support the use of EMD during routine, nonsurgical debridement of periodontal pockets as measured 3 months post SRP."
03/01/1988 - "To date, there are no ultrastructural studies that have examined untreated chronic periodontal pockets immediately following dental debridement with an oral irrigation device. "
03/01/1982 - "[Evaluation of the efficacy of subgingival scaling in relation to the depth of the periodontal pockets]."
12/01/1980 - "Following initial treatment comprising scaling, root planing and instructions in plaque control measures, deepened periodontal pockets were eliminated by the use of an apically repositioned flap procedure including osseous surgery to eliminate bony defects. "
10/01/1986 - "The aim of the present study was to relate shifts in the composition of subgingival plaque in periodontal pockets to alterations of the clinical periodontal conditions following a single course of subgingival scaling and root planing during a period of professional supragingival plaque control. "
06/01/1993 - "One single, well-executed subgingival scaling and root-planning procedure in deep, diseased periodontal pockets, followed by oral hygiene training and professional mechanical tooth-cleaning (PMTC) at need-related intervals, will prevent further loss of periodontal attachment. "
12/01/2004 - "Professional advice should be given on oral hygiene and diet, and treatments should include dental scaling, and root planing of the associated periodontal pockets to reduce the bacterial loading. "
07/01/2015 - "The aim of this retrospective multicenter study was to verify the efficacy of Nd:YAG laser in the treatment of periodontal pockets infected by Epstein-Barr Virus (EBV) and Herpes Simplex Virus 1 (HSV1). "
07/01/2015 - "Efficacy of the ND:YAG laser therapy on EBV and HSV1 contamination in periodontal pockets."
01/01/2005 - "The purpose of the present study was to assess the effects of Nd:YAG laser irradiation into periodontal pockets with or without the combination of local antibiotic application on clinical parameters and microbiological prevalence. "
06/01/2004 - "[Antibacterial effect of Nd:YAG laser in periodontal pockets decontamination: a in vivo study]."
03/01/2003 - "In contrast to previous SEM studies, the histological examination indicated thermal changes within the hard tissue bordering the periodontal pocket following Er:YAG laser irradiation."
|5.||Oral Hygiene (Dental Hygiene)
06/01/2008 - "The aim of this study was to examine the association between intensity and duration of cigarette smoking with the presence of periodontal pockets at a young adult age in relation to oral hygiene practices. "
09/01/2013 - "Dental and dental hygiene students must acquire the skill of measuring periodontal pockets and learn to identify the bottom of a pocket, especially of deep periodontal pockets. "
06/01/2012 - "Logistic regression found that age, gender, number of teeth present and oral hygiene were all strongly associated with the prevalence of 4 mm+ periodontal pockets. "
10/01/2009 - "Among the other investigated parameters, age and customary oral hygiene practices were correlated with periodontal pocket formation and clinical attachment loss. "
11/01/2008 - "Indices of oral hygiene level and periodontal status (dental plaque index, gingival index and periodontal pockets' depth) were significantly worsened in patients with diabetes. "