Periodontal Abscess

Localized circumscribed purulent area of inflammation in the periodontal tissue. It is a derivative of marginal periodontitis and commonly associated with suprabony and infrabony pockets and interradicular involvements, in contrast to periapical abscess which is attributable to pulp necrosis.

Also Known As:

Networked: 74 relevant articles (5 outcomes, 9 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Periodontitis
2.	Infections
3.	Periodontal Diseases (Periodontal Disease)
4.	Suppuration
5.	Arteriovenous Malformations (Arteriovenous Malformation)

Experts

1.	Chen, Jiazhen: 3 articles (01/2019 - 02/2014)
2.	Wu, Xingwen: 3 articles (01/2019 - 02/2014)
3.	Xu, Meng: 3 articles (01/2019 - 02/2014)
4.	Yu, Liying: 3 articles (01/2019 - 02/2014)
5.	Zhang, Wenhong: 3 articles (01/2019 - 02/2014)
6.	Alonso, Bettina: 2 articles (01/2018 - 01/2018)
7.	Feres, Magda: 2 articles (01/2018 - 01/2018)
8.	Herrera, David: 2 articles (01/2018 - 01/2018)
9.	Retamal-Valdes, Belén: 2 articles (01/2018 - 01/2018)
10.	He, Junlin: 2 articles (01/2015 - 02/2014)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Periodontal Abscess:

1.	Anti-Bacterial Agents (Antibiotics)IBA 06/01/2000 - "The aim of this short-term open parallel longitudinal clinical study was to compare the clinical and microbiological efficacy of 2 different antibiotic regimes in the treatment of acute periodontal abscesses. " 01/01/2015 - "The most common indication for the prescribed antibiotics was periapical or periodontal abscess (44%). " 12/01/2012 - "To isolate and culture the predominant anaerobes from the periodontal abscesses, and to test the antibiotic susceptibility and drug resistant genes of the strains. " 12/01/2012 - "[Distribution of anaerobes in periodontal abscess and its resistance to antibiotics]." 12/01/2007 - "Subsequently, an incision and systemic antibiotics were necessary because of the formation of a periodontal abscess. "
2.	Minocycline (Cyclops)FDA LinkGeneric 03/01/2008 - "Topical treatment with minocycline in pockets with acute periodontal abscess was effective in reducing the bacterial counts as shown by the microbiological investigation using PadoTest 4.5." 03/01/2008 - "In all the patients, pockets with acute periodontal abscess were irrigated with sterilized physiological saline, and in the test group, 2% minocycline hydrochloride ointment was applied once into the pocket in addition. " 09/11/2023 - "The study included 63 patients who had received treatment for acute periodontal abscesses through drainage supplemented with 1 of 3 types of adjunctive medications during their initial visit (visit 1; baseline): 1) saline irrigation (the control group), 2) 2% minocycline ointment (the TM group), or 3) 300 mg/mL doxycycline irrigation (the TD group). " 09/11/2023 - "The objective of this retrospective clinical study was to provide evidence supporting the adjunctive local application of doxycycline solution or minocycline ointment, in conjunction with drainage, for the treatment of acute periodontal abscesses. " 09/11/2023 - "Comparing the clinical effects of local administration of minocycline ointment and doxycycline solution in the treatment of acute periodontal abscesses: a retrospective clinical study."
3.	Doxycycline (Periostat)FDA LinkGeneric 11/01/1991 - "If any site exhibited greater than 2 mm loss of GAL or a periodontal abscess, patients were administered either 100 mg doxycycline per day for 3 weeks or placebo. " 03/01/1991 - "When a site exhibited greater than or equal to 2 mm loss of GAL or a periodontal abscess, patients were administered either doxycycline at a dosage of 200 mg to start and 100 mg per day for 3 weeks, or a placebo. " 10/01/1990 - "If any site exhibited greater than or equal to 2 mm loss of GAL or a periodontal abscess, patients were administered either 100 mg Doxycycline per day for 3 weeks or placebo. " 05/01/2000 - "Doxycycline therapy may be used for acute periodontal abscess and if the conditions are accompanied by general symptoms. " 09/11/2023 - "The study included 63 patients who had received treatment for acute periodontal abscesses through drainage supplemented with 1 of 3 types of adjunctive medications during their initial visit (visit 1; baseline): 1) saline irrigation (the control group), 2) 2% minocycline ointment (the TM group), or 3) 300 mg/mL doxycycline irrigation (the TD group). "
4.	Ointments (Pastes)IBA 03/01/2008 - "In all the patients, pockets with acute periodontal abscess were irrigated with sterilized physiological saline, and in the test group, 2% minocycline hydrochloride ointment was applied once into the pocket in addition. " 09/11/2023 - "The study included 63 patients who had received treatment for acute periodontal abscesses through drainage supplemented with 1 of 3 types of adjunctive medications during their initial visit (visit 1; baseline): 1) saline irrigation (the control group), 2) 2% minocycline ointment (the TM group), or 3) 300 mg/mL doxycycline irrigation (the TD group). " 09/11/2023 - "The objective of this retrospective clinical study was to provide evidence supporting the adjunctive local application of doxycycline solution or minocycline ointment, in conjunction with drainage, for the treatment of acute periodontal abscesses. " 09/11/2023 - "Comparing the clinical effects of local administration of minocycline ointment and doxycycline solution in the treatment of acute periodontal abscesses: a retrospective clinical study."
5.	ChloridesIBA 11/01/1984 - "[Lysozymal chloride for periodontal abscess--clinical studies]."
6.	Metronidazole (Metric)FDA LinkGeneric 02/01/1992 - "When either a periodontal abscess or greater than 2 mm loss of gingival attachment was observed, metronidazole was administered (250 mg every 8 hours) for 10 days. " 09/01/1990 - "[Clinical evaluation of metronidazole in the treatment of the periodontal abscesses]." 01/01/2010 - "Symptoms commenced after the third dose of Metronidazole therapy prescribed for a recurrent periodontal abscess. " 09/01/1990 - "On the basis of clinical examination it has been found that Metronidazole which was applied in 24 patients suffering from periodontal abscesses produced healing effects, lessened their pain and did not cause any side reactions. " 07/01/2023 - "The association of penicillin + metronidazole is prescribed to 37.3% of ulcero-necrotizing gingivitis patients, 47% of patients presenting aggressive periodontitis, 42.5% of chronic periodontitis patients, and 65.5% of cases presenting periodontal abscess. "
7.	Penicillins (Penicillin)FDA Link 04/01/1993 - "Ten of 24 (42%) patients receiving systemic penicillin therapy developed clinical evidence of periodontal abscesses. " 12/01/1978 - "While the patient was convalescing with penicillin therapy, a dental survey revealed the presence of periodontal abscesses which were drained by exodontia. " 07/01/2023 - "Dentists prescribed penicillin to 37.3% of cases presenting ulcero-necrotizing gingivitis and 62.3% of patients presenting periodontal abscess. " 07/01/2023 - "The association of penicillin + metronidazole is prescribed to 37.3% of ulcero-necrotizing gingivitis patients, 47% of patients presenting aggressive periodontitis, 42.5% of chronic periodontitis patients, and 65.5% of cases presenting periodontal abscess. "
8.	Azithromycin (Zithromax)FDA LinkGeneric 06/01/2007 - "Four cases with periodontal abscesses were treated with scaling/root planing in conjunction with systemic azithromycin. " 09/29/2020 - "Bacterial species associated with periodontal abscess demonstrated some level of antimicrobial resistance to amoxicillin, metronidazole and tetracycline while antibiotic resistance to azithromycin could not be demonstrated."
9.	neodymium pyrocatechin disulfonate (NPD)IBA 01/01/2018 - "To critically evaluate the existing literature on acute lesions occurring in the periodontium (periodontal abscesses [PA], necrotizing periodontal diseases [NPD], and endo-periodontal lesions [EPL]) to determine the weight of evidence for the existence of specific clinical conditions that may be grouped together according to common features. " 01/01/2018 - "To critically evaluate the existing literature on acute lesions occurring in the periodontium (periodontal abscesses [PA], necrotizing periodontal diseases [NPD], and endo-periodontal lesions [EPL]) to determine the weight of evidence for the existence of specific clinical conditions that may be grouped together according to common features. "
10.	Aurora KinasesIBA 01/01/2023 - "Here, we report, for the first time, amplifications of aurora kinase genes (AURKA/B) in a patient with a history of periodontal abscess and the presence of a remaining nodule, diagnosed with Burkitt lymphoma and Epstein-Barr virus, and /HIV positive. "

Therapies and Procedures

1.	Debridement 01/01/1998 - "Radiographic bone fill following debridement of a periodontal abscess. " 01/01/2003 - "Mechanical debridement methods, including drainage of pus for acute periodontal abscesses, should be considered the first line treatment for most periodontal diseases. " 04/01/1990 - "It was concluded that in patients with advanced periodontal disease, systemic antibiotic therapy without subgingival debridement may change the composition of the subgingival microbiota, thus favouring the outburst of multiple periodontal abscesses."
2.	Dental Scaling 10/01/2012 - "The method of supra- and subgingival scaling was rapid and effective in treatment of acute periodontal abscesses." 06/01/2007 - "Four cases with periodontal abscesses were treated with scaling/root planing in conjunction with systemic azithromycin. "
3.	Therapeutics 11/01/1991 - "Eighty-two patients with a recent history of periodontal abscesses and/or loss of gingival attachment level (GAL) despite active periodontal therapy were enrolled in a double-blind, randomized, placebo-controlled trial. " 03/01/1991 - "Twenty-seven patients with a recent history of periodontal abscesses and/or loss of gingival attachment level (GAL) despite active periodontal therapy were enrolled in a double-blind, randomized, placebo-controlled trial. " 10/01/1990 - "82 patients with a recent history of periodontal abscesses and/or loss of gingival attachment (GAL) despite active periodontal therapy were enrolled in a double-blind, randomized, placebo-controlled trial. " 09/01/2008 - "The aim of this review is to present the current status of the occurrence and management of a periodontal abscess during supportive periodontal therapy (SPT). " 09/01/2008 - "Periodontal abscess during supportive periodontal therapy: a review of the literature."
4.	Oral Hygiene (Dental Hygiene) 09/08/2019 - "This case report describes the management of a patient who presented with an acute periodontal abscess secondary to poor oral hygiene. " 09/05/2019 - "Malocclusion impaired proper dental hygiene, which led to bone loss and development of a periodontal abscess between mandibular canines and lateral incisors. " 09/01/2004 - "A 44-year-old female patient was referred by a local periodontist for evaluation of multiple painless gingival lesions that clinically resembled pyogenic granulomas or periodontal abscesses, but with an uncharacteristic multifocal presentation in the background of good oral hygiene. " 04/01/2015 - "Oral signs of neglect are easily identifiable and are: poor oral hygiene, halitosis, Early Childhood Caries (ECC), odontogenous infections (recurrent and previous abscesses), periodontal disease, aptha lesions as a consequence of a nutritional deficiency status. "
5.	Tooth Extraction (Tooth Extractions) 04/01/2021 - "Root fracture, deep pockets lesions and periodontal abscess were observed in DARCT with a value of 8-9(P=0.027), leading to tooth extraction. " 12/01/1977 - "Oral mucosa incision can allow several interventions: cellulitis or periodontal abscess opening, gingival tissue excision or repositioning or at least exposure of alveolar bone for tooth extraction or infrabony pockets' treatment. " 02/01/2021 - "Tetanus has been associated with tooth extraction, root canal therapy, gross caries, periodontal abscess and intraoral soft tissue trauma. "