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Constrictive Pericarditis

Inflammation of the PERICARDIUM that is characterized by the fibrous scarring and adhesion of both serous layers, the VISCERAL PERICARDIUM and the PARIETAL PERICARDIUM leading to the loss of pericardial cavity. The thickened pericardium severely restricts cardiac filling. Clinical signs include FATIGUE, muscle wasting, and WEIGHT LOSS.
Also Known As:
Pericarditis, Constrictive; Pick Disease of Heart; Constrictive Pericarditides; Heart Pick's Disease; Pericarditides, Constrictive; Pick Disease, Heart; Picks Disease, Heart; Pick's Disease of Heart
Networked: 937 relevant articles (38 outcomes, 59 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Restrictive Cardiomyopathy
2. Cardiac Tamponade
3. Pericarditis
4. Pericardial Effusion
5. Pulmonary Tuberculosis

Experts

1. Oh, Jae K: 15 articles (01/2021 - 03/2002)
2. Schaff, Hartzell V: 12 articles (01/2021 - 01/2004)
3. Klein, Allan L: 11 articles (10/2021 - 02/2004)
4. Ntsekhe, Mpiko: 8 articles (08/2022 - 01/2013)
5. Imazio, Massimo: 7 articles (03/2022 - 11/2010)
6. Mayosi, Bongani M: 7 articles (03/2018 - 11/2010)
7. Kwon, Deborah H: 6 articles (10/2021 - 11/2011)
8. Greason, Kevin L: 5 articles (12/2021 - 09/2017)
9. Daly, Richard C: 5 articles (01/2021 - 04/2012)
10. Dearani, Joseph A: 5 articles (01/2021 - 01/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Constrictive Pericarditis:
1. Anti-Bacterial Agents (Antibiotics)IBA
2. Brain Natriuretic Peptide (Natrecor)FDA Link
3. ColchicineFDA LinkGeneric
4. SteroidsIBA
5. Immunoglobulin G (IgG)IBA
6. TolvaptanFDA Link
7. Prednisone (Sone)FDA LinkGeneric
8. Tissue Plasminogen Activator (Alteplase)FDA Link
9. Fibrinolytic Agents (Antithrombotic Agents)IBA
10. Clozapine (Clozaril)FDA LinkGeneric

Therapies and Procedures

1. Pericardiectomy
2. Therapeutics
3. Operative Surgical Procedures
09/01/1981 - "Total excision of both pericardic sac and epicardium is the basic surgical procedure for chronic constrictive pericarditis. "
12/01/1997 - "Pericardiectomy is the only effective surgical procedure for constrictive pericarditis, but we have often experienced a lack of significant improvement of hemodynamic parameters, this being attributed to the presence of residual constriction. "
03/01/2018 - "We concluded that pericardiotomy is an established surgical procedure and is excellent indication to constrictive pericarditis."
01/01/2011 - "Pericardial effusion should be drained percutaneously (in local anesthesia) and pericardiectomy performed for constrictive pericarditis before any major surgical procedure. "
01/01/1995 - "Post CPB echo study, which was performed after hemodynamic stabilization, modified the surgical strategy in 13 cases (10.9%) avoiding 1 predetermined surgical procedure (tricuspid ring annuloplasty) and a new surgery in another case, leading to a 3 non-predetermined surgical procedures (by showing significative tricuspid regurgitation), to a further surgery in the same valve in 6 patients (mitral paravalvular leak with significative regurgitation in 1P, another mitral prosthesis dysfunction in 1P, residual mitral valve insufficiency after mitral valve repair in 3 P and aortic prosthesis dysfunction in 1 P), to a intraaortic counterpulsation balloon device in 1 P and to new CPB due to an insufficient extraction of calcified pericardium in one case of constrictive pericarditis. "
4. Electrodes (Electrode)
5. Thoracotomy