Peptic Ulcer Perforation

03/01/2012 - "Among the various sutureless techniques, fibrin glue has proved to be effective in the treatment of peptic ulcer perforation as an alternative to classical suture repair. "

04/01/2022 - "Double Peptic Ulcer Perforation due to Cumulative Effects of Post-surgery Stress and NSAIDs: A Rare Event in Surgical Practice."
12/01/2006 - "Of the 2,061 patients hospitalized with peptic ulcer perforation, 38% were current NSAID users. "
12/01/2006 - "We examined 30-day mortality after peptic ulcer perforation associated with the use of traditional NSAIDs and newer selective cyclo-oxygenase-2 (COX-2) inhibitors. "
12/01/2006 - "Nonsteroidal anti-inflammatory drug (NSAID) use is a strong risk factor for peptic ulcer perforation, yet little is known about the outcome of this condition among NSAID users. "
04/01/1985 - "We suggest that the elderly especially women are unduly susceptible to NSAID associated peptic ulcer perforation, and discuss factors that may account for this."

05/01/2013 - "The problem of peptic ulcer perforation with its complication, can be decreased by decreasing the perforation -operation time interval, which as per our study, appeared to be the single most important mortality and morbidity indicator in peptic ulcer perforation."
05/01/2013 - "The Perforation-Operation time Interval; An Important Mortality Indicator in Peptic Ulcer Perforation."
11/30/2009 - "[Preoperative delay in patients with peptic ulcer perforation: a clinical audit from the Danish National Indicator Project]."

08/05/2022 - "The aim of our study was to investigate the prognostic role of platelet/albumin ratio in patients treated under emergency conditions for peptic ulcer perforation (PUP). "
08/05/2022 - "The effect of platelet-albumin ratio on mortality and morbidity in peptic ulcer perforation."
01/01/2009 - "Finding that shock upon admission, reduced albumin blood levels upon admission, renal insufficiency upon admission and preoperative metabolic acidosis are independently related to 30-day mortality could indicate that patients with peptic ulcer perforation are septic upon admission, and thus might benefit from a perioperative care protocol with early source control and early goal-directed therapy according to The Surviving Sepsis Campaign. "

12/01/2006 - "30-day mortality after peptic ulcer perforation among users of newer selective COX-2 inhibitors and traditional NSAIDs: a population-based study."
12/01/2006 - "Current use of NSAIDs, including COX-2 inhibitors, is associated with a poor prognosis for patients hospitalized with peptic ulcer perforation."

05/01/2019 - "Conclusion: This study results suggested that PLR, NLR, and lymphocyte count values could be used as new biomarkers to identify the mortality risk in patients operated on for peptic ulcer perforation."
05/01/2019 - "Background: Despite surgical treatment of peptic ulcer perforation (PUP), the high rates of morbidity and mortality have motivated researchers to search for new laboratory markers to predict morbidity and mortality. "
05/01/2019 - "Is the Platelet to Lymphocyte Ratio a Potential Biomarker for Predicting Mortality in Peptic Ulcer Perforation?"

04/01/2008 - "* In this population-based study of 1271 patients hospitalized with peptic ulcer perforation, tramadol appeared to increase mortality at least as much as NSAIDs. "

09/01/2009 - "In this experimental study, we treated peptic ulcer perforation in the first portion of the duodenum using an ePTFE (expanded polytetrafluoroethylene) soft tissue graft and compared results with primary suturing. "

06/01/1997 - "Peptic ulcer perforation before and after the introduction of H2-receptor blockers and proton pump inhibitors."
01/01/2009 - "Despite the introduction of histamine H2-receptor antagonists, proton-pump inhibitors and the discovery of Helicobacter pylori, both the incidence of emergency surgery for perforated peptic ulcer and the mortality rate for patients undergoing surgery for peptic ulcer perforation have increased. "

03/01/1987 - "During this period, 151 peptic ulcer perforations occurred, 25 (17%) associated with steroid use. "
03/01/1987 - "A ten-year (1974 to 1984) retrospective chart review was conducted to find all patients with peptic ulcer perforation associated with steroid treatment. "
03/01/1987 - "Peptic ulcer perforation associated with steroid use."
05/01/2012 - "The Peptic Ulcer Perforation (PULP) score - comprised eight variables with an adjusted odds ratio of more than 1.28: 1) age > 65 years, 2) active malignant disease or AIDS, 3) liver cirrhosis, 4) steroid use, 5) time from perforation to admission > 24 h, 6) pre-operative shock, 7) serum creatinine > 130 μM, and 8) the four levels of the ASA score (from 2 to 5). "

11/14/2023 - "This study aimed to compare the clinical outcomes of the clinical outcomes of laparoscopic and open sutures for peptic ulcer perforation (PPU). "
01/01/2012 - "The simple suture laparoscopic repair of peptic ulcer perforation without an omental patch."
10/01/2003 - "Being female and awaiting for primary suture for peptic ulcer perforation were significant predictors of preoperative state anxiety. "
10/01/2003 - "Being female, waiting for primary suture for peptic ulcer perforation operation, and helplessness and self-blaming coping appeared as significant predictors of anxiety specific to surgery. "
01/01/2005 - "[Peptic ulcer perforation: suture or gastrectomy ? "

10/01/2022 - "The present study aimed to compare the short-term outcomes of laparoscopy and laparotomy techniques in the surgical treatment of peptic ulcer perforation. "
04/13/2016 - "Peptic ulcer perforation was repaired after abdominal laparotomy. "
12/30/2022 - "Anaesthesiology perspective on a multidisciplinary approach to optimal perioperative management of a patient with giant peptic ulcer perforation caused by the physiological stress of a thyroid storm necessitating emergent laparotomy."
04/01/2018 - "This prospective observational study had a time based sample of 101 perforation peritonitis cases admitted to the surgical wards of a tertiary care center from February 2015 to January 2016 who underwent laparotomy, diagnosed to have peptic ulcer perforation and underwent simple closure with an omental patch. "
07/01/2013 - "He presented again 7 days later with recurring epigastric pain and had exploratory laparotomy on the presumptive diagnosis of peritonitis, probably due to peptic ulcer perforation. "

03/01/2000 - "In peptic ulcer perforation, a conservative treatment trial can be given in selected cases. "
01/01/2005 - "High-risk peptic ulcer perforation patients can be managed by putting in an intra-abdominal drain supported by conservative treatment."
01/01/1997 - "[Conservative treatment of gastroduodenal peptic ulcer perforations: indications and results]."

08/01/1994 - "Delayed treatment after peptic ulcer perforation reduced survival, increased complication rates, and caused prolonged hospital stay. "
12/01/2015 - "This study aimed to compare laparoscopic peptic ulcer perforation closure with conventional open closure in terms of operative time, postoperative analgesia, complications, hospital stay, and return to routine activities. "

12/01/2015 - "This study aimed to compare laparoscopic peptic ulcer perforation closure with conventional open closure in terms of operative time, postoperative analgesia, complications, hospital stay, and return to routine activities. "